cortex

摘要： The cerebral cortex is one of the most complex structures of the mammalian central nervous system and accounts for the extraordinary cognitive abilities in primates and humans.Since the 19th century,neur ons have been believed to be the main players in the building of the brain,yet astrocytes also play a crucial role as fundamental building blocks of the cerebral cortex complexity.

摘要： The hippocampus is involved in important brain functions such as learning and memory,spatial navigation,fear processing,and social behavior(Dudek et al,2016).The most prominent areas of the hippocampus are typically denoted as the dentate gyrus and the three areas of the cornu ammonis(CA1,CA2,and CA3).Discovered by Lorente de Nó(1934),the CA2 region of the hippocampus is a relatively small area interposed between CA3 and CA1 that forms the nexus linking the input of the entorhinal cortex to the output of CA1(Chevaleyre and Siegelbaum,2010).

摘要： Traumatic brain injury(TBI)represents a significant cause of disability worldwide.It creates a vast array of damaging macro-and microscopic changes in the affected brain area(s),ranging from neuronal cell death,changes in structural spine integrity and dynamics to axonal injury and overall neuronal circuit disruption,ultimately leading to functional and cognitive deficits in both humans and animal models(Nudo,2013).

摘要： Selective vulnerability of excitatory neurons in Alzheimer’s disease(AD):AD is the most common form of dementia;however,the pathogenesis of AD is largely unknown.One of the characteristic features of AD is the formation of intracellular neurofibrillary tangles(NFTs).NFTs are abnormal accumulates of misfolded tau protein,which may eventually cause neuronal death and neurodegeneration(Jack et al.,2018).In the early stages of AD progression,not all neurons are equally vulnerable to tau aggregates.Previous studies have shown that large pyramidal neurons in the entorhinal cortex(EC)are specifically vulnerable to pathological tau accumulation(Fu et al.,2017).This selective vulnerability of excitatory neurons to tau pathology is one of the fundamental questions needed to be answered in AD research.

摘要： The adult cortex has long been regarded as non-neurogenic.Whether injury can induce neurogenesis in the adult cortex is still controversial.Here,we report that focal ischemia stimulates a transient wave of local neurogenesis.Using 5′-bromo-2′-deoxyuridine labeling,we demonstrated a rapid generation of doublecortin-positive neuroblasts that died quickly in mouse cerebral cortex following ischemia.Nestin-Cre^(ER)-based cell ablation and fate mapping showed a small contribution of neuroblasts by subventricular zone neural stem cells.Using a mini-photothrombotic ischemia mouse model and retrovirus expressing green fluorescent protein labeling,we observed maturation of locally generated new neurons.Furthermore,fate tracing analyses using PDGFRα-,GFAP-,and Sox2-Cre^(ER) mice showed a transient wave of neuroblast generation in mild ischemic cortex and identified that Sox2-positive astrocytes were the major neurogenic cells in adult cortex.In addition,a similar upregulation of Sox2 and appearance of neuroblasts were observed in the focal ischemic cortex of Macaca mulatta.Our findings demonstrated a transient neurogenic response of Sox2-positive astrocytes in ischemic cortex,which suggests the possibility of inducing neuronal regeneration by amplifying this intrinsic response in the future.

摘要： 随着社会快速发展,系统性、行业性火灾风险持续增加,对人们生命财产安全造成严重威胁。为址,全国各地先后新建、改建消防综合训练基地,以提升复杂灾情条件下消防救援队伍灭火救援综合能力。然而传统实战训练演练虽能有效提高消防救援队伍整体救援能力,但其依然存在弊端。为有效解决这些弊端,基于集成Cortex嵌入式技术,构建出一套消防装备模拟训练系统,测试结果显示,基于Cortex的消防装备模拟训练系统稳定性较强,训练成本低、效率高。

摘要： The prelimbic cortex(PL),a key brain.region of the medial prefrontal cortex(mPFC),plays an important role in cognitive ability,emotional regulation and pain modulation.However,there was stil a lack of systematic connective mapping in the PL.Therefore,to analyze the afferent projections to the mouse PL,the fluorescence gold(FG)and rabies virus(helper viruses(AAV2/9-DIO-EGFP-TVA and AAV2/9-DIO-G)and RV-EnvA-OG-dsRed)were injected respectively into the PL of C57 mice,PV-Cre and CaMKII-Cre mice.The FG labeled projections neurons were observed in some cortex regions,including mPFC,anterior cingulate cortex(ACC),insular cortex(IC),claustrum(CLA).They were also found in some nuclei of the thalamus,such as paraventricular nucleus of thalamus(PVT),mediodorsal nucleus of thalamus(MD),paratenial nucleus of thalamus(PT),centrolateral nucleus of thalamus(CL),.ventromedial nucleus of thalamus(VM),rhomboid nucleus of thalamus(Rh),and reuniens nucleus of thalamus(Re).

摘要： The basal ganglia is a critical subcortical nuclei in several parallel and closed circuits,which mainly modulate thalamus-cortex activity.Dysfunction in any one of these loops connecting cortex can lead to movement and/or mood disorders.To understand cellular complexity,differential gene expression and transcriptional regulatory network of human basal ganglia under normal condition,we performed single cell RNA sequencing of 2424 cells sampled from the basal ganglia of human postmortem brains including caudate,putamen,substantia nigra and globus pallidus.

摘要： The formation of cerebral cortex is a highly ordered and strictly regulated development process,involving the production of various neural cells and the formation of nerve networks.The proliferation,differentiation,migration and stratification of NSCs are the cytological basis of cerebral cortex development.It is.

摘要： Ventral tegmental area(VTA),which is well-documented as a modulatory center of reward and addiction,has been demonstrated to participate in pain processing.In addition,insula cortex(IC)has also been proved to be related with maintenance of neuropathic pain.In the present study,in order to clarify whether there exist dopaminergic projections from the VTA to the IC,retrograde and anterograde tracing methods combined with immunofluorescent histochemical staining were applied.The results revealed that almost all VTA-IC-projecting neurons originated from the VTA were dopaminergic neurons,with smaller amount of GABAergic neurons sending projection fiberss to the IC.

摘要： 本文研究显示,CORTEX FRAXINI药材有明显的抗痛风性关节炎作用、抑制血尿酸生成和镇痛作用,而该药材中的香豆素类可能是其主要有效组分.

摘要： 本文研究显示,CORTEX FRAXINI药材有明显的抗痛风性关节炎作用、抑制血尿酸生成和镇痛作用,而该药材中的香豆素类可能是其主要有效组分.

摘要： 本文研究显示,CORTEX FRAXINI药材有明显的抗痛风性关节炎作用、抑制血尿酸生成和镇痛作用,而该药材中的香豆素类可能是其主要有效组分.

摘要： 本文研究显示,CORTEX FRAXINI药材有明显的抗痛风性关节炎作用、抑制血尿酸生成和镇痛作用,而该药材中的香豆素类可能是其主要有效组分.

摘要： 本文研究显示,CORTEX FRAXINI药材有明显的抗痛风性关节炎作用、抑制血尿酸生成和镇痛作用,而该药材中的香豆素类可能是其主要有效组分.

摘要： 本文研究显示,CORTEX FRAXINI药材有明显的抗痛风性关节炎作用、抑制血尿酸生成和镇痛作用,而该药材中的香豆素类可能是其主要有效组分.

摘要： 本发明提供一种基于Cortex‑M0+微控制器仿真MSI数字逻辑芯片的方法。通过UART或可选的WIFI设置所仿真芯片的型号，端口状态通过WIFI发送到PC机，实现电平可视化显示。从而提供一个高性价比、易于使用的MSI数字逻辑芯片仿真方法。

摘要： 本发明公开了一种应用Cortex‑M芯片系统的数据存储方法及Cortex‑M芯片系统，涉及计算机存储设备技术领域。其中，一种应用Cortex‑M芯片系统的数据存储方法，具体包括：周期性检查Cortex‑M芯片系统是否处于工作模式，若未处于工作模式，则调整所述芯片系统的工作模式为待机模式；通过预设方式唤醒所述芯片系统，并调整所述芯片系统的工作模式为主模式；加载所述芯片系统中MRAM存储器里已初始化的数据，恢复所述芯片系统的正常工作模式；在所述MRAM存储器中按照预设的存储方式对数据执行存储操作。

摘要： 本申请涉及一种基于Cortex‑M处理器的循环神经网络加速方法、系统和介质，其中，该方法包括：根据循环神经网络的共性基础算子设置MCR指令和CDP指令，其中，共性基础算子包括矩阵乘法算子、向量运算算子、Sigmoid激活算子、Tanh激活算子和量化算子；通过MCR指令对循环神经网络协处理器的内部寄存器进行配置；基于配置好的内部寄存器，通过CDP指令启动所述循环神经网络的共性基础算子，通过本申请，解决了循环神经网络算法在处理器执行中的低效、高成本和不灵活的问题，实现了通过协处理器指令集执行循环神经网络所需要的基础算子，对于算法多变的应用领域可降低重构硬件的成本，降低了系统的功耗和成本。

摘要： 本申请涉及一种基于Cortex‑M处理器的卷积神经网络加速方法、系统和介质，其中，该方法包括：根据卷积神经网络的共性基础算子设置MCR指令和CDP指令，其中，共性基础算子包括卷积算子、Relu激活算子、池化算子、查表算子和量化算子；通过MCR指令对卷积神经网络协处理器的内部寄存器进行配置，再通过CDP指令启动卷积神经网络的共性基础算子，通过本申请，解决了卷积神经网络算法在处理器执行中的低效、高成本和不灵活的问题，实现了通过协处理器指令集执行卷积神经网络所需要的基础算子，对于算法多变的应用领域可降低重构硬件的成本。

摘要： 本发明公开了一种基于Cortex‑M4和Android系统的电解质测量仪器，涉及电解质检测设备技术领域。本发明包括电解质分析仪本体，电解质分析仪本体的前端端面两侧均安装有柜门，电解质分析仪本体的上表面前端一侧设置有控制箱；废液箱的内部上方安装有活性炭网，固定板的下表面两侧分别安装有伸缩杆和触点；散热组件包括散热箱和吸热板；电解质分析仪本体的一侧外壁下方后端设置有防护组件，防护组件包括防护框和转板。本发明通过散热组件实现水冷和风冷进行散热，提高散热效果，同时利用防护组件对内部接口起到保护的作用，避免灰尘和水进入，并且通过废液箱和控制箱清除废液箱中的异味，且可以远程操作控制其运行并观察废液箱中的废液含量。

摘要： 本发明属于传感器技术领域，具体提供一种基于Cortex‑M3内核的可配置全集成温度传感器，用以解决传统时域温度传感器存在的集成度不高、可配置性低等问题。本发明在温度传感电路部分采用了自偏置电流源结构，产生PTAT电流，由该电流驱动环形振荡器的尾电流源，通过控制负载电容，输出与温度正相关的感应频率，并通过方波整形电路，输出可供FDC识别的感应方波，最终输出数字码，有效提高温度传感器的准确性；同时，引入Corte x‑M3内核构成微处理器，有效控制温度传感电路的开启或关闭，实现FDC模块的精度配置、以匹配不同应用场景的测量精度需求，并将FDC模块的输出数据的转换为温度值输出，最终实现温度传感器在CMOS工艺下的全集成设计。

摘要： 本发明涉及一种基于Cortex‑A9的无人智能平台信息控制系统，包括：外壳及其内部的控制电路；所述控制电路包括：至少一个基于ARMCortex‑A9内核的可扩展信息分发解算控制板卡、交换机板卡和宽电压输入电源转换板卡。本发明可实现对无人智能平台各种信息的采集收发解算并控制无人智能平台按照既定轨迹航行，对无人智能平台搭载的外设完成远程无线自动控制，完成岸基远程操控无人智能平台。

摘要： 本发明属于车牌识别技术领域，且公开了基于Cortex‑A8的车牌识别系统，包括数据采集模块、数据处理模块、数据传输模块与应用模块，所述数据采集模块包括有车辆检测器与摄像头。本发明为了实现对路边停车位进行实时检测与车辆统计、对路内停车位进行实时性管理，本发明提供一种基于Cortex‑A8的嵌入式平台的车牌识别系统，在嵌入式平台上利用车辆检测技术与图像识别技术，实现对路内停车位使用情况的实时检测与车牌自动识别，并将检测数据通过4G模块实时地上传到服务器，从而实现对路边停车位的无人监控。

摘要： 本发明涉及工业物联网技术领域，尤其涉及一种基于cortex‑M3的工业物联网网络管理控制器，包括基于cortex‑M3内核的CPU处理器、网络管理模块、通信模块和触摸显示屏，基于cortex‑M3内核的CPU处理器和网络管理模块通过总线连接，所述的网络管理模块用于完成网络数据的转发和传输，通信模块和触摸显示屏分别与基于cortex‑M3内核的CPU处理器相连接。本发明具备实时性好，集成度高，通用性好，实用性强的优点。

摘要： 本实用信息新型公开了一种基于Cortex‑M3的图像去雾硬件加速SoC芯片，包括中央处理器cortex‑M3、GPIO、AHB总线控制器、图像处理模块、数据存储模块、过程控制模块、结果显示模块；过程控制模块中设置有拨码开关；拨码开关与GPIO电连接，通过GPIO将信号发送给中央处理器cortex‑M3实现图片的切换。本实用新型系统整体性能稳定，测试效果良好，人机交互友好，图片去雾的保真度和还原度都达到了较高的水平，能够可靠有效的进行雾天图像去雾。