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球结膜

球结膜的相关文献在1989年到2021年内共计234篇,主要集中在眼科学、内科学、中国医学 等领域,其中期刊论文212篇、会议论文2篇、专利文献20篇;相关期刊135种,包括微循环学杂志、中国微循环、临床眼科杂志等; 相关会议2种,包括全国中医、中西医结合眼科学术交流会、全国中医药心脑病中药用药临床评价研讨会等;球结膜的相关文献由508位作者贡献,包括张兴儒、李青松、郭灵常等。

球结膜—发文量

期刊论文>

论文:212 占比:90.60%

会议论文>

论文:2 占比:0.85%

专利文献>

论文:20 占比:8.55%

总计:234篇

球结膜—发文趋势图

球结膜

-研究学者

  • 张兴儒
  • 李青松
  • 郭灵常
  • 李冰
  • 符之瑄
  • 赵黎
  • 韩秀娴
  • 刘旺华
  • 单毅
  • 周小青
  • 期刊论文
  • 会议论文
  • 专利文献

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    • Hu Liang; Shu Xupeng; Xu Yangyang; Cheng Jian; Xu Zhiqiang; Wang Jianhua; Lyu Fan
    • 《中华眼科杂志》  | 2019年
    • 摘要: Objective To explore the changes of microcirculation of the bulbar conjunctiva after wearing the contact lens and the relationship between contact lens discomfort and bulbar conjunctiva microcirculation.Methods Prospective cohort study.The postgraduate students from School of Ophthalmology & Optometry and School of Biomedical Engineering of Wenzhou Medical University were included in this prospective cohort study.The subjects wore soft contact lenses,and the right eye was selected as the experimental eye.The ocular surface disease index (OSDI) questionnaire,Schirmer I and tear break-up time tests were completed before and after wearing the contact lens,and the conjunctival blood flow velocity and microvascular network density were also assessed by using functional slit lamp biomicroscopy.The changes of the indicators after wearing the contact lens were observed and the correlation between the subjective feelings of the wearers and the microcirculation parameters of the bulbar conjunctiva and the main factors affecting the subjective feelings of the wearers were analyzed.Results Twenty-seven subjects were enrolled in the study,including 8 males and 19 females,aged (22.7±1.6) years.The OSDI score was 11.860± 7.783 before wearing the contact lens and 24.017± 12.181 after wearing the contact lens.The comparison before and after wearing the contact lens was statistically significant (t=-4.356,P<0.001).The conjunctival blood flow velocity was (0.534±0.132) mm/s before wearing the contact lens and (0.587±0.134) mm/s after wearing the contact lens.The comparison was statistically significant before and after wearing the lens (t=-2.076,P=0.048).OSDI was positively correlated with blood flow velocity at 1 month after wearing the contact lens (correlation coefficient r=0.383,P=0.048).The test results of the independent variables in the generalized estimating equation model showed that time and blood flow velocity were statistically significant (P<0.05).Conclusions The blood flow velocity of the bulbar conjunctiva was increased after wearing the contact lens,and the contact lens discomfort of the wearers was positively correlated with the blood flow velocity of the bulbar conjunctiva.%目的 探讨角膜接触镜配戴前后球结膜微循环的改变及其与主观不适症状的关系.方法 前瞻性队列研究.本研究纳入温州医科大学眼视光学院、生物工程学院双眼配戴月抛软性角膜接触镜的在校研究生进行研究,取右眼作为实验对象.于戴镜前与戴镜后1个月进行眼表疾病指数(OSDI)量表填写,检查基础泪液分泌(Schirmer Ⅰ)试验和泪膜破裂时间(TBUT),并采用功能性裂隙灯生物显微镜对球结膜血流速度和微血管网密度进行评估,观察各指标在戴镜前后的变化并分析配戴者主观感受与球结膜微循环参数的相关性以及影响配戴者主观感受的主要因素.采用配对t检验分析戴镜前后的OSDI、血流速度、微血管网密度的差异;采用配对样本Wilcoxon符号秩和检验分析戴镜前后Schirmer Ⅰ和TBUT的差异.球结膜微循环参数与OSDI的相关性采用Pearson相关分析,与干眼指标的相关性采用Spearman秩相关分析;采用广义估计方程评估影响角膜接触镜配戴主观感受的主要因素.结果 27名受试者纳入本研究,其中男性8名,女性19名,年龄(22.7±1.6)岁.OSDI评分戴镜前为(11.860±7.783)分,戴镜后为(24.017±12.181)分,戴镜前后对比差异具有统计学意义(t=-4.356,P<0.001),球结膜血流速度戴镜前为(0.534±0.132) mm/s,戴镜后为(0.587±0.134)mm/s,戴镜前后对比差异具有统计学意义(t=-2.076,P=0.048).戴镜后1个月OSDI与血流速度呈正相关(r=0.383,P=0.048),广义估计方程模型中自变量的检验结果显示,时间、血流速度均有统计学意义(P<0.05).结论 角膜接触镜配戴后球结膜血流速度增加,配戴者的主观不适症状与球结膜血流速度呈正相关.
    • 罗慧红
    • 《护理实践与研究》  | 2015年
    • 摘要: 目的:探讨放松训练对自体角膜缘上皮联合球结膜移植治疗翼状胬肉手术患者的影响。方法:选取2011年8月~2012年11月在我院眼科住院治疗的翼状胬肉手术患者150例,随机等分为观察组和对照组,对照组给予常规护理,观察组患者给予常规手术护理加上放松训练。比较两组患者焦虑抑郁情绪及对护理服务的满意度。结果:观察组患者对护理服务的满意率高于对照组(P<0.05),观察组患者出院时的抑郁、焦虑评分明显低于对照组(P<0.05)。结论:放松训练对翼状胬肉患者有积极的影响,提高了患者对护理服务的满意度,改善了翼状胬肉患者的焦虑抑郁情绪。
    • 《中国美容医学》  | 2015年
    • 摘要: Objective To investigate the beautifying eyes by removing eyelid spots and bulbar conjunctiva brown spots with operation. Methods From November 2009 to April 2014,We treated 98 cases with eyelid spots and bulbar conjunctiva brown spots by diseased tissues resection.And the wound did not sew up. Results Followed up for 1-2 years after the operation,93 patients in 98 cases received satisfactory effects,5 cases had more satisfactory results. Conclusion It has good eye aesthetic effects by removing eyelid spots and bulbar conjunctiva brown spots with operation.%目的:探讨通过手术方法去除眼睑裂斑及球结膜褐色斑,达到眼部美学效果。方法:2009年11月-2015年4月,笔者对98例眼睑裂斑、球结膜褐色斑患者,采用表面麻醉和肿胀浸润麻醉后,将病变处球结膜浅层充分分离后剪除病变组织,创口边缘不缝合,自行愈合。结果:术后随访1~2年,98例中93例获得了理想的术后效果,术区洁白、光滑,5例效果比较理想。结论:通过手术方法去除眼睑裂斑及球结膜褐色斑可达到良好的美容效果。
    • 邵洪波; 姚月明; 魏伟
    • 《中国医学创新》  | 2015年
    • 摘要: 目的:探讨酸烧伤后家兔球结膜微循环变化规律及机制,以及酸烧伤后家兔血液流变性的变化,探讨其对机体血液粘滞性的影响。方法:以健康成年家兔为实验对象,随机分为对照组及烧伤组,复制酸烧伤模型,分别在烧伤后即刻、烧伤后30 min、烧伤后1 h、烧伤后2 h观测球结膜微循环;在两组伤后即刻,伤后8 h、伤后24 h、伤后48 h四个时相进行采血,检测全血黏度(ηb)、全血还原黏度(ηr)、血浆黏度(ηp)、血沉(ESR)、血沉方程K值(K)、红细胞比容(HCT)、纤维蛋白原(FB)、红细胞刚性指数(TK)、红细胞聚集指数(EAI)各相应数值,分别进行统计学分析比较。结果:烧伤组四个时相的总积分值分别与对照组比较差异均有统计学意义(P<0.05);两组ηb及ηr进行比较后,四个时相在同切变率下,烧伤组伤后各值明显高于对照组(P<0.05);两组ηp、HCT、ESR、K、FB、EAI、TK比较后,烧伤组伤后各时相所得值均高于对照组(P<0.05)。结论:机体受到酸烧伤后,球结膜微循环有严重的改变,出现不同程度的微循环障碍,而且影响血液在血管中的流动速度,导致血液流变性发生变化。%Objective:To observe the changes in bulbar conjunctiva microcirculation of acid burned rabbits during early burning,to study the regularity and characters of its changing,and changes of hemorheology,then explore its effect on blood viscosity.Method:The healthy adult rabbits were selected as experimental objects,and were randomly divided into control group and burn group,duplicate the model of acid burn,when two groups after injury immediately, after injury 30 min,1 h,2 h,the bulbar conjunctiva microcirculation were observed,blooding when two groups after injury immediately,after injury 8,24,48 h,the parameters included whole-blood viscosity(ηb),whole-blood re-store viscosity(ηr),plasma viscosity(ηp),erythrocyte sedimentation rate(ESR),K value of ESR equation(K), hematocrit(HCT),fibrinogen(FB),erythrocyte stiffen index(TK),erythrocyte aggregation index(EAI),test data were measurement data,and were analyzed by t test.Result:Total credit value of four phases respectively compared with the control group,there was significant difference(P<0.05). Compared the two groupsηb andηr,and four phase at the same shear rate,the value in burn injury group was higher than that in control group(P<0.05);compared two groups ofηp,HCT,ESR,K,FB,EAI,TK,the values of burn group in each phase were higher than those of control group (P<0.05).Conclusion:After acid burns,bulbar conjunctiva microcirculation changes severely,affecting blood flow velocity in the blood vessels,leading to changes in blood rheology.
    • 龚宝明; 沈国栋; 张俊虎
    • 《转化医学电子杂志》  | 2015年
    • 摘要: 破伤风是常和创伤相关联的一种特异性感染,病菌是破伤风梭菌,为专性厌氧型,革兰氏染色阳性。平时存在于人畜的肠道,随粪便排出体外,以芽孢状态分布于自然界。本文主要将球结膜外伤致破伤风诊治体会报道如下。
    • 芮慧强
    • 《启蒙》  | 2020年
    • 摘要: 芮大夫:你好!我女儿今年6岁了,一次偶然发现孩子右眼鼻侧球结膜有一块浅黄色隆起,没有高出结膜多少,孩子说不疼也不痒,观察1-2个月不见长大。我拍了两张照片寄去,不一定清楚,请您帮忙看一下到底是什么问题。谢谢!你好!能给6岁的孩子拍出眼睛照片,孩子就算够棒的、够配合的了。根据你介绍的病情,病变有3个特点:(1)偶然发现;(2)右眼鼻侧球结膜有一浅黄色略微隆起,没有高出结膜多少;(3)不疼也不痒,没有逐渐长大。我觉得右眼结膜皮样脂肪瘤的可能性比较大,有时间可以去眼科医院再确认一下。
    • 李青松; 赵黎; 张兴儒; 符之瑄; 项敏泓; 柯梅青; 莫利娟; 张桂丽
    • 《国际眼科杂志》  | 2014年
    • 摘要: 目的:利用光学相干断层扫描技术( optical coherence tomography,OCT)观察流行性出血性结膜炎治疗前后结膜厚度及形态变化。  方法:使用 OCT 对上海中医药大学附属普陀医院眼科2013-05/12收治的初发1~2 d的29例36眼流行性出血性结膜炎患者进行球结膜厚度测量及形态学观察,并在治疗7,14 d后复诊时再次测量患者的球结膜厚度并观察球结膜形态变化。  结果:患者29例36眼中,治疗7 d流行性出血性结膜炎治愈(27眼)患者中治疗前球结膜全层厚度(344.00±59-91μm)较治疗后球结膜全层厚度(230.19±22.16μm)更厚,差异有统计学意义(t=11.75,P<0.01);治疗前球结膜上皮层厚度(56.52±6.19μm)较治疗后球结膜上皮层厚度(51.37±5.53μm)更厚,差异有统计学意义( t=4.61, P<0.01);治疗前球结膜固有层厚度(287.11±60.56μm)较治疗后球结膜固有层厚度(178.81±20.20μm)更厚,差异有统计学意义(t=10.69,P<0.01)。治疗14d,36眼全部治愈,治疗前球结膜全层厚度(361.39±65.56μm)较治疗后(233.44±22.57μm)更厚,差异有统计学意义( t=14-45,P<0.01);治疗前球结膜上皮层厚度(55.50±6-72μm)较治疗后(46.67±5.24μm)更厚,差异有统计学意义( t=10.06, P<0.01);治疗前球结膜固有层厚度(305.61±66.02μm)较治疗后(186.78±21.82μm)更厚,差异有统计学意义(t=13.11,P<0.01)。  结论:利用OCT能测量流行性出血性结膜炎的球结膜厚度,并发现流行性出血性结膜炎患者球结膜上皮层、固有层和全层厚度都明显增厚,并且随着疾病的转归球结膜下积液和球结膜层间积液、固有层水肿首先消失,为流行性出血性结膜炎的临床治疗提供评价±据。%AIM: To observe thickness and morphological changes of bulbar conjunctiva pre- and post epidemic hemorrhagic conjunctivitis ( EHC ) therapy by optical coherence tomography ( OCT) . METHODS: Observed morphological changes and measured the bulbar conjunctiva thicknesses of 29 cases (36 eyes) of incipient (1-2d) EHC patients, who were received and treated by department of ophthalmology, the Putuo Affiliated Hospital of Shanghai University of Traditional Chinese Medicine from May 2013 to December 2013, by OCT. Then measured the thickness again on 7, 14d after the therapy. RESULTS: Among 29 patients (36 eyes), 7d after the EHC therapy, in 27 cured eyes, the full-thickness ( before 344. 00±59. 91μm, after 230. 19±22. 16μm, t=11. 75, P<0-01); epithelial thickness ( before 56. 52±6. 19μm, after 51. 37±5. 53μm, t=4. 61, P<0. 01); and stromal thickness (before 287. 11±60. 56μm, after 178. 81±20. 20μm, t=10. 69, P<0. 01) of patients' bulbar conjunctiva were thicker than values measured after therapy with significant difference. Significant difference was also found for full-thickness ( before 361. 39±65. 56μm, after 233. 44±22. 57μm, the difference was statistically significant, t=14. 45, P<0. 01);epithelial thickness ( before 55. 50±6. 72μm, after 46. 67±5-24μm, t=10. 06, P<0. 01) and stromal thickness ( before 305. 61±66. 02μm, after 186. 78±21. 82μm, t=13. 11, P<0-01 ) of patients' bulbar conjunctiva between values measured before and 14d after therapy. CONCLUSION: The OCT is able to measure the thickness of bulbar conjunctiva in EHC patients. An significant increase was found in full, epithelial and stromal thickness of EHC patients' bulbar conjunctiva. With recovery from the disease, subepithelial fluid, interlaminar fluid and edema of the bulbar conjunctival stroma faded away firstly, which provide references for clinical therapies of the EHC.
    • 程燕
    • 《母婴世界》  | 2017年
    • 摘要: 目的:讨论自体角膜缘干细胞移植治疗翼状胬肉的临床疗效.方法:采用自体角膜缘干细胞移植,治疗翼状胬肉的30眼,随访,一年到两年.结果:30眼术后2眼复发.结论:自体角膜缘干细胞移植治疗翼状胬肉疗效安全,复发率低.
    • 赵黎; 李青松; 张兴儒
    • 《国际眼科杂志》  | 2015年
    • 摘要: Abstract•AlM:To observe thickness and morphological changes of cornea and bulbar conjunctiva pre- and post acute angle closure glaucoma ( AACG ) therapy by optical coherence tomography ( OCT) .•METHODS: Twenty - five patients with AACG were recruited. lntraocular pressure ( lOP ) and morphological characteristic of cornea and conjunctiva were measured at their first visit, 1, 2 and 3d after they began the treatments.•RESULTS:The corneal epithelium thickness and corneal thickness of patients with acute attack of angle closure glaucoma were 72. 76±11. 95μm and 589. 40±66. 91μm; the conjunctival epithelial layer thickness was 58. 88±12. 87μm;the thickness of conjunctive stroma was 299. 76±94. 86μm;the conjunctival full thickness was 358. 64±102. 55μm. The corneal epithelium thickness and corneal thickness at the first day of the treatment were 69. 28±12. 65μm and 579. 04± 67. 88μm;the conjunctival epithelial layer thickness was 57. 04 ± 12. 05μm;the thickness of conjunctive stroma was 282. 44±91. 47μm;the conjunctival full thickness was 339. 48± 100. 28μm. the corneal epithelium thickness and corneal thickness at the second day of treatment were 66. 76 ± 11. 42μm and 563. 32 ± 63. 87μm;the conjunctival epithelial layer thickness was 54. 76 ± 11. 01μm;the thickness of conjunctive stroma was 267. 00 ± 98. 54μm;the conjunctival full thickness was 322. 16 ± 106. 12μm. the corneal epithelium thickness and corneal thickness of the third day treatment are 65. 16 ± 12. 25μm and 550. 36 ± 71. 48μm; the conjunctival epithelial layer thickness was measured 53. 36± 10. 29μm;the thickness of conjunctive stroma was 252. 76± 99. 32μm;the conjunctival full thickness was 306. 52 ± 107. 31μm. The difference of lOP, corneal epithelial thickness, corneal thickness, conjunctival epithelial layer thickness, conjunctival stroma thickness and conjunvtival full thickness had statistically significant(P<0. 05).•CONCLUSlON:The corneal and conjunctival thickness in patients at acute attack of angle closure glaucom increase. The edema level decreases with lOP.%目的::利用光学相干光断层扫描技术( optical coherence tomography,OCT)观察急性闭角型青光眼治疗前后角膜和结膜厚度及形态的变化。方法:收集急性闭角型青光眼患者25例,对初诊、治疗第1、2、3d的眼压与角膜结膜特征对比分析。结果:急性闭角型青光眼发作时角膜上皮厚度、全层厚度分别为72.76±11.95、589.40±66.91μm;结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为58.88±12.87、299.76±94.86、358.64±102.55μm;治疗第1d角膜上皮厚度、全层厚度分别为69.28±12.65、579.04±67.88μm;结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为57.04±12.05、282.44±91.47、339.48±100.28μm;治疗第2d角膜上皮厚度、全层厚度分别为66.76±11.42、563.32±63.87μm;结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为54.76±11.01、267.00±98.54、322.16±106.12μm;治疗第3d角膜上皮厚度、全层厚度分别为65.16±12.25、550.36±71.48μm;结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为53.36±10.29、252.76±99.32、306.52±107.31μm;治疗前、治疗第1、2、3d时4个测量时间点的眼压、角膜上皮厚度、角膜全层厚度、结膜上皮厚度、结膜固有层厚度和结膜全层厚度差异都有统计学意义(P<0.05)。结论:青光眼急性发作时角膜结膜水肿厚度增加,并随眼压的降低而变薄。
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