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洗胃液

洗胃液的相关文献在1977年到2022年内共计129篇,主要集中在临床医学、内科学、预防医学、卫生学 等领域,其中期刊论文112篇、会议论文2篇、专利文献1830篇;相关期刊80种,包括黑河科技、现代中西医结合杂志、中国中医急症等; 相关会议2种,包括第三届世界灾害护理大会、2002年中国药学会医院药学学术年会等;洗胃液的相关文献由267位作者贡献,包括刘慧、刘国荣、岳红霞等。

洗胃液—发文量

期刊论文>

论文:112 占比:5.76%

会议论文>

论文:2 占比:0.10%

专利文献>

论文:1830 占比:94.14%

总计:1944篇

洗胃液—发文趋势图

洗胃液

-研究学者

  • 刘慧
  • 刘国荣
  • 岳红霞
  • 左桂香
  • 张力
  • 朱帆
  • 李泓胜
  • 李骏
  • 王婷
  • 管癸芬
  • 期刊论文
  • 会议论文
  • 专利文献

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    • 于中锴; 刘君华; 曲爱君
    • 摘要: 甲醇中毒较为罕见,多由误服含甲醇成分的酒类或饮料所致。甲醇中毒后可引起中枢神经系统、眼睛、肝脏、肾脏等机体的损害,同时常合并代谢性酸中毒,是严重威胁人民健康的中毒性疾病之一。笔者急诊治疗2例重度甲醇中毒患者。现报告如下。一、病例介绍病例1:患者女性,52岁,2019年4月15日误服"玻璃水"约400~600 mL,当时出现头晕、头痛、恶心症状,约2 h后在当地乡镇医院给予洗胃,洗胃液初为蓝色,后为澄清,并给予护胃、补液治疗。
    • 高永霞
    • 摘要: 农业生产中,我国很多地方都通过喷洒农药来防止病虫害,在一定程度上,这种农业管理方式提升了农产品的产量,保证了农民效益。与此同时,农药的喷洒也带来了较为严重的安全问题。尤其是随着有机磷农药的应用,因农药中毒的患者不断增加,这就需要对患者及时的进行洗胃,避免患者发生生命危险。那么一旦人们发生有机磷农药中毒时,处理及时、正确与否,直接关系到病人的生命和将来的生活质量。洗胃是如何操作的呢,今天就给大家来科普一下。
    • 刘慧; 翟凤平; 徐华; 魏婧; 许铁
    • 摘要: Objective To explore the effect of gastrolavage with different osmotic pressure solutions on gastric mucosa, plasma osmotic pressure, plasma PGE2 and ET-1 in rabbits, and investigate the value and meaning of the parameters such as plasma PGE2, ET-1 and POP for the evaluation of gastric mucosa damage degree. Methods A total of 32 rabbits were randomly divided into four groups with 8 in each group:control (NC) group, clear water (CW) group, 0.45%sodium chloride solution (HS) group, and 0.9%sodium chloride solution (NS) group. After the rabbits were anesthetized, they were given gastric lavage with homemade improvised gastric lavage apparatus. The blood samples of each group were collected at pre-gastrolavage and post-gastrolavage. PGE2 and ET-1 in plasma were measured by ELISA. At the end of the experiment, the rabbits’stomach were removed after being sacrificed. The injury level of the gastric mucosa was observed by macroscopic and light. Results Before gastrolavage, plasma osmotic pressure, PGE2 and ET-1 did not show any significant difference among the groups (P>0.05). After gastrolavage, plasma osmotic pressure in CW group and HS group significantly decreased and were lower than that in NC group and NS group (P<0.05). The expression value of plasma PGE2 in NS group, HS group and CW group significantly increased and were higher than that in NC group (P<0.05). The expression value of plasma ET-1 in NS group, HS group and CW group significantly increased and were higher than that in NC group (P<0.05). The gastric mucosa DI and EDS in NS group, HS group, CW group were significantly higher than that in NC group (P<0.05). Correlation analysis reflected that after gastrolavage POP and gastric mucosa damage degree were significantly negative correlated, while plasma PGE2/ET-1 and gastric mucosa damage degree were significantly positive correlated. Conclusion Gastrolavage with different osmotic pressure solution may result in the changes of POP, plasma PGE2 and ET-1 in rabbit, and the changes may reflect the degree of gastric mucosa damage.%目的:研究不同渗透压液体洗胃对胃黏膜、血浆渗透压(POP)、血浆前列腺素E2(PGE2)和内皮素-1(ET-1)的影响,探讨血浆PGE2、ET-1和POP等参数对洗胃导致胃黏膜损伤程度评估的价值与意义。方法将32只日本长耳大白兔随机分为正常对照组(NC组)、清水洗胃组(CW组)、0.45%氯化钠溶液洗胃组(HS组)、0.9%氯化钠溶液洗胃组(NS组),每组8只。CW组、HS组、NS组分别用清水、0.45%氯化钠溶液和0.9%氯化钠溶液洗胃;NC组仅置胃管不洗胃。在置胃管前及洗胃后,采动脉血液标本测定血浆PGE2、ET-1和POP;然后用气栓法处死兔,取出胃,在肉眼和光镜下评价胃黏膜损伤程度。结果洗胃前各组POP、PGE2以及ET-1相比,差异无统计学意义。洗胃后,CW组和HS组POP显著下降,显著低于NC组和NS组,差异有统计学意义(P<0.05);NS组、HS组和CW组血浆PGE2浓度显著升高,显著高于NC组,差异有统计学意义(P<0.05);NS组、HS组和CW组血浆ET-1浓度显著升高,高于NC组,差异有统计学意义(P<0.05)。NS组、HS组和CW组DI/EDS显著高于NC组,差异有统计学意义(P<0.05)。相关性分析表明,洗胃后POP与胃黏膜损伤程度呈显著负相关,血浆PGE2和ET-1与胃黏膜损伤程度呈显著正相关。结论不同渗透压液体洗胃可导致家兔POP、血浆PGE2和ET-1浓度的改变,这种改变可在一定程度上反映胃黏膜损伤程度。
    • 刘慧; 许铁; 周莹
    • 摘要: Objective To study the effect of gastrolavage with different osmotic pressure solution on gastric mucosa in rabbits.Methods Thirty-two rabbits were randomly divided into four equal groups:normal control (NC) group, clear water (CW) group, 0.45% sodium chloride solution ( HS) group, 0.9%sodium chloride solution ( NS) group.After the rabbits were anesthetized, we give them gastric lavage with homemade improvised gastric lavage apparatus.The blood samples of each group were collected at pre -gastrolavage and post -gastrolavage, plasma electrolytes were measured and plasma osmotic pressure was calculated.At the end of the experiment, the rabbits were sacrificed, then stomachs were removed.The injury level of the gastric mucosa was observed by the naked eyes and light. Results Before gastrolavage, plasma electrolytes and osmotic pressure did not show significant difference among the groups (P>0.05).After gastrolavage, plasma sodium concentration in CW group and HS group [(128.63 ±7.13)mmol/L, (131.88 ±4.55)mmol/L] significantly decreased and were lower than that in NC group and NS group [(136.38 ±3.58)mmol/L],(140.13 ±0.83)mmol/L,P<0.05].Plasma potassium concentration in CW group, HS group and NS group [(2.13 ±0.35)mmol/L,(2.19 ±0.36)mmol/L,(2.11 ±0.24)mmol/L]significantly decreased and were lower than that in NC group[(2.73 ±0.41)mmol/L,P<0.05].Plasma calcium concentration in CW group, HS group and NS group [(1.23 ±0.12)mmol/L,(1.34 ±0.13)mmol/L,(1.38 ±0.10)mmol/L] significantly decreased compared with that of pre-gastrolavage [(1.38 ±0.12)mmol/L,(1.42 ±0.08)mmol/L, (1.43 ±0.08)mmol/L,P<0.05].Plasma calcium concentration in CW group was lower than that in NS group (P<0.05).Plasma osmotic pressure in CW group and HS group [(269.32 ±13.94)mmol/L,(278.96 ±8.66) mmol/L] significantly decreased and were lower than that in NC group and NS group [(290.74 ±6.11)mmol/L,(292.56 ±2.59)mmol/L,P<0.05].The gastric mucosa epidermal damage score (EDS) and damage index (DI) in NS group, HS group and CW group (2.88 ±2.03, 3.50 ±2.14, 5.50 ±2.20, 28.88 ±14.63, 42.63 ±21.03, 48.25 ±17.27) were significantly higher than that in NC group (0.25 ±0.46, 0.38 ±0.74) (P<0.05).The gastric mucosa EDS in NS group (2.88 ±2.03) were significantly lower than that in HS group and CW group (3.50 ±2.14, 5.50 ± 2.20) (P<0.05).The gastric mucosa DI in CW group (48.25 ±17.27) were significantly higher than that in NS group ( 28.88 ±14.63 ) ( P <0.05 ) .Conclusion Gastrolavage with clear water and 0.45%sodium chloride solution may cause gastric mucosa damage and the decrease of the plasma electrolytes and osmotic pressure.Gastrolavage with 0.9% sodium chloride solution has lighter damage on gastric mucosa and no obvious effect on plasma osmotic pressure.Different osmotic solution gastric lavage leads to different degree of water electrolyte disorder associated with different degree of gastric mucosa damage.%目的探讨不同渗透压液体洗胃对兔胃黏膜和血浆渗透压的影响。方法将32只日本长耳大白兔随机分为正常对照组( NC组)、清水组( CW组)、0.45%氯化钠溶液组( HS组)、0.9%氯化钠溶液组(NS组),每组8只。根据重力洗胃法原理进行洗胃。洗胃参数:洗胃液温度37~38°C,进出压力10~15 kPa,进液量25 mL/kg,周期30 s,持续时间40~50 min。 CW组、HS组、NS组分别用清水、0.45%氯化钠溶液和0.9%氯化钠溶液进行洗胃;NC组仅置胃管不洗胃。在置胃管前及洗胃后,采动脉血;然后用气栓法处死兔,取出胃,在肉眼和光镜下评价胃黏膜损伤程度。结果洗胃前各组兔血浆电解质、渗透压比较差异无统计学意义。洗胃后CW组和HS组血钠浓度[(128.63±7.13) mmol/L 和(131.88±4.55) mmol/L]显著下降,与 NC 组(136.38±3.58)mmol/L和NS组(140.13±0.83)mmol/L比较,差异有统计学意义(P<0.05);CW组、HS组和NS组血钾浓度[(2.13±0.35)mmol/L、(2.19±0.36)mmol/L和(2.11±0.24) mmol/L]显著下降,低于NC组(2.73±0.41) mmol/L,差异有统计学意义( P<0.05);CW组、HS组和NS组血钙浓度[(1.23±0.12)mmol/L、(1.34±0.13)mmol/L和(1.38±0.10)mmol/L]显著下降, CW 组显著低于 NS 组( P <0.05)。 CW 组和 HS 组洗胃前后血浆渗透压显著下降[(295.59±11.75)mmol/L vs (269.32±13.94)mmol/L和(290.99±5.52)mmol/L vs (278.96±8.66)mmol/L)],也显著低于洗胃后NC组(290.74±6.11) mmol/L和NS组(292.56±2.59) mmol/L,差异有统计学意义( P<0.05)。 NS组、HS组和CW组胃黏膜损伤指数(28.88±14.63、42.63±21.03和48.25±17.27)较NC组(0.38±0.74)显著升高,CW组显著高于NS组(均P<0.05);NS组、HS组和CW组胃黏膜上皮损伤评分(2.88±2.03、3.50±2.14和5.50±2.20)较NC组(0.25±0.46)显著升高,CW组高于NS组(均P<0.05)。结论用清水和0.45%氯化钠溶液洗胃可造成兔胃黏膜损伤,引起血钠、血钾、血钙和血浆渗透压下降;0.9%氯化钠溶液洗胃造成的胃黏膜损伤较轻,对血钠和血浆渗透压无显著影响,并可减缓血钙浓度的下降程度。不同渗透压液体洗胃导致兔不同程度的水电解质紊乱与胃黏膜损伤程度不同有关。
    • 姜友斌
    • 摘要: 本院2010年6月~2011年6月收治的48例有机磷农药中毒患者随机分为试验组和对照组各12例,试验组采用大量洗胃液洗胃,对照组采用常规洗胃法,两组其余治疗方式相同,比较两组患者胆碱酯酶活性恢复至正常值的75%的时间和在院治疗时间。结果试验组胆碱酯酶活性恢复至75%正常值的时间和平均治疗时间均显著低于对照组(P<0.05)。综上所述,临床上采用大量洗胃液洗胃能够较早的减少患者胃肠道内有毒物质残留,进而减少有毒物质地吸收,减少了患者的在院治疗时间,值得临床推广应用。
    • 谢佩玲; 顾玉琴; 管癸芬
    • 摘要: 目的 探讨0.9%温盐水在催吐洗胃中的应用效果.方法 将100例符合催吐洗胃条件的患者随机分为对照组和观察组,对照组49例使用温开水催吐,观察组51例使用0.9%温盐水催吐,比较两组催吐洗胃的效果.结果 观察组催吐时间(3.92±2.35)min,比对照组提前,差异有统计学意义(P<0.05);洗胃液总入量(3 421.57±1 581.91)mL和总出量(3 306.86±1 514.07)mL均明显减少,差异有统计学意义(P<0.05);观察组洗胃时间(30.00±10.98)min短于对照组,差异有统计学意义(P<0.05).结论 0.9%温盐水是安全便捷的催吐洗胃液.
    • 徐伶; 褚安红
    • 摘要: 目的探讨固定冷热比例配制洗胃液在急诊洗胃中的应用价值。方法采用回顾性对照研究的方法,以2009年~2012年因口服中毒至苏州大学附属第二医院急诊科进行洗胃术的患者作为研究对象,根据洗胃液的配置方法将其分为随机冷热水比例组(随机组)和固定冷热比例组(固定组),比较两组患者洗胃液配置时间、洗胃液温度、洗胃液温度变异、洗胃液量、洗胃时间、胃出血的发生率与回访满意度。结果共有277例患者进入该回顾性调查,两组患者洗胃液的用量和洗胃时间均无明显差异,固定组配液时间为(2.3±0.1)min,随机组配液时间为(4.1±0.2)min,两组间比较具有统计学差异(P<0.05);随机组洗胃液温度为(35.2±2.1)°C,其温度变异度为(1.1±0.2)°C,而固定组洗胃液温度为(36.1±0.1)°C,其温度变异为(0.5±0.1)°C,明显小于随机组(P<0.05);随机组出现胃出血患者13例,固定组5例,随机组回访满意度为95%,固定组回访满意度99.1%。结论固定冷热比例法配制洗胃液明显缩短洗胃液配置时间,更有利于控制洗胃液的温度。
    • 罗天玉; 张红梅; 陈凤玲; 马小萍; 夏秋江; 王青丽; 张希洲
    • 摘要: 目的:观察纯净水加氯化钠在口服药物中毒中的临床应用效果.方法:将248例口服中毒患者随机分为观察组(127例)和对照组(121例).对照组以纯净水洗胃,观察组以纯净水加氯化钠(每桶纯净水10 L加氯化钠90 g,相当于0.9%氯化钠)洗胃,两组均用自制特殊加温装置加热到36°C.观察洗胃前后的平均动脉压、心率、血常规、血钠和血钾情况,并留剩余洗胃液送培养.结果:洗胃后两组血清钠浓度、平均动脉压水平的差异有统计学意义(P<0.01).剩余洗胃液送培养结果,对照组大肠杆菌超标,观察未见超标大肠杆菌生长.结论:纯净水水源充足,符合饮用水卫生标准,加入一定量的氯化钠后,接近生理盐水的浓度,能避免洗胃时出现的低钠血症及血压下降现象,减少院内交叉感染.%Objective:The clinical application of pure water and sodium chloride in gastric lavage of oral drug poisoning patients. Method: Two hundred and forty-eight oral drug poisoning patients were divided into the observation group (127 cases) and the control group (121 cases) randomly. 36°C clean water was used for gastric lavage in the control group. The observation group had gastric lavage with 36°C pure water and sodium chloride(a barrel of pure water 10 L with sodium chloride 90 g,as much as 0. 9% sodium chloride). The water was heated to 36°C with homemade special warming device. The mean arterial pressure,heart rate,hemogram,blood sodium and potassium during gastric lavage were observed and gastric juice was sent to culture. Result: There were significant differences (P<0. 01)in the concentration of serum sodium,mean arterial pressure level between the two groups. The culture results showed that the E. Coli was overproof in control group, while there was no overproof in the observation group. Conclusion:Purified water is abundant,and meet the drinking water health standards. It is close to the concentration of the physiological saline with a certain amount of sodium chloride. It can avoid hyponatremia and the fall of blood pressure after gastric lavage in oral drug poisoning patients,and reduce cross infection.
    • 陈木全; 陈兰; 郑木珍
    • 摘要: 目的分析小儿急诊洗胃的方法与临床效果。方法选取2011年1月至2013年1月收治的需急诊洗胃的小儿患者19例,均根据患儿的具体情况慎重进行洗胃处理,并对5岁以上与以下患儿的一次插管成功率、洗胃成功率、并发症发生率以及患儿家长满意率评价比较。结果5岁以上患儿一次插管成功率100.0%;成功洗胃率100.0%,未见并发症发生,患儿家长满意率100.0%。5岁以下患儿一次插管成功率85.7%;成功洗胃率85.7%,并发症发生率14.3%,患儿家长满意率85.7%。5岁以上患儿洗胃效果更明显(P<0.05)。结论对小儿进行急诊洗胃治疗时,应慎重处理,对洗胃液的选用与用量,胃管的选用与插管的深度等进行综合控制,以提高患儿临床洗胃效果。%Objective To analyze emergency gastric lavage for children and its clinical effects. Methods Between January 2011 and January 2013, 19 pediatric patients admitted for emergency gastric lavage were selected, and the gastric lavage treatment was performed cautiously according to the children’ s conditions. A comparison between the children older than ifve and the children less than ifve years old was made in terms of the success rate of one-time intubation, success rate of gastric lavage, complication rate, and parent’s satisfaction rate. Results For the children older than ifve, the success rate of one-time intubation, success rate of gastric lavage, and parent’s satisfaction rate were 100.0%respectively, without the occurrence of complications. For the children less than ifve years old, the success rate of one-time intubation, success rate of gastric lavage, complication rate, and parent’s satisfaction rate were 85.7%, 85.7%, 14.3%, and 85.7%, respectively. Compared with the effects of gastric lavage on the children less than ifve years old, those on the children older than ifve were signiifcantly better (P<0.05). Conclusion Emergency gastric lavage for children should be performed cautiously. In order to improve the clinical effects of gastric lavage on children, the selection and dosage of gastric lavage lfuid, selection of gastric tube, and intubation depth should be administrated comprehensively.
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