摘要:
Objective To explore the role of oxygen inhalation in treatment of patients with urinary tract infection after endoscopic lithotripsy. Methods The clinical data of 60 patients with urinary tract infection after laparoscopic lithotripsy in this hospital during August 2016 to August 2018 were retrospectly reviewed and analyzed. These patients were divided into two groups by random table method according to their serial number (1 - 60) by SPSS 21. 0. Patients in group 1 were treated with routine treatment plus oxygen inhalation for 6 hours (routine treatment group,n = 30),patients in another group were treated with routine therapy plus oxygen inhalation for 24 hours (oxygen inhalation group,30 cases),and the VAS scores,duration for drainage tube,retention time of nephrostomic tube,duration for application of antibiotics,hospitalization time,high fever,positive blood culture,decrease of hemoglobin level and recurrence rate after operation of these two groups were statistically analyzed. Results The VAS scores of patients in oxygen inhalation group were significantly lower than those of conventional treatment group (P < 0. 05). The indwelling time of drainage tube,nephrostomy tube,antibiotic application time and duration of hospitalization in patients of oxygen inhalation group were significantly shorter than those of conventional treatment group (P < 0. 05). The recurrence rate of oxygen inhalation group was significantly lower than that of conventional treatment group 13. 3% (4 /30) (P < 0. 05). The difference in incidence of fever [6. 7% (2 / 30) vs. 3. 3% (1 /30) ],positive blood culture [3. 3% (1 /30) vs. 6. 7% (2 /30) ]and hemoglobin reduction [6. 7% (2 /30) vs. 3. 3% (1 / 30) ]between these two group was not significant (P > 0. 05). Conclusion Oxygen inhalation can significantly reduce VAS scores,shorten indwelling time of drainage tube and nephrostomy tube,and duration for application of antibiotics and hospitalization and treatment of infection in these patients after endoscopic lithotripsy for urinary calculi. It is helpful in controlling infection and reduce the incidence of severe infection.%目的 探讨吸氧在泌尿道结石腔镜碎石术后感染治疗中的作用.方法 回顾性选取2016年8月至2018年8月上海市杨浦区市东医院收治的泌尿道结石腔镜碎石术后感染患者60例,将入组患者按照治疗方法 分为两组:一组常规治疗+ 吸氧6 h(常规治疗组,n = 30),一组常规治疗+ 吸氧24 h(吸氧治疗组,n = 30),统计分析两组患者的疼痛视觉模拟评分(VAS)、引流管和肾造瘘管留置时间、抗生素应用时间、住院时间,以及术后高热、血培养阳性、血红蛋白降低情况及复发情况.结果 吸氧治疗组患者的VAS评分显著低于常规治疗组(P < 0.05),引流管留置时间、肾造瘘管留置时间、抗生素应用时间、住院时间均显著短于常规治疗组(P < 0.05),复发率(0)显著低于常规治疗组[13.3%(4 /30)](P < 0.05),但两组患者的术后高热[6.7%(2 /30)vs.3.3%(1 /30)]、血培养阳性[3.3%(1 /30)vs.6.7%(2 / 30)]、血红蛋白降低发生率[6.7%(2 /30)vs.3.3%(1 /30)]差异均无统计学意义(P > 0.05).结论 吸氧在泌尿道结石腔镜碎石术后感染治疗中能够显著降低VAS评分,缩短引流管和肾造瘘管留置时间、抗生素应用时间、住院时间,有助于感染的控制,降低重症感染的发生率.