您现在的位置: 首页> 研究主题> catch

catch

catch的相关文献在1981年到2021年内共计113篇,主要集中在常用外国语、肿瘤学、电影、电视艺术 等领域,其中期刊论文111篇、专利文献2篇;相关期刊74种,包括疯狂英语阅读版(含光盘)、初中生必读、苏州教育学院学报等; catch的相关文献由169位作者贡献,包括Daisuke Funabara、Satoshi Kanoh、Yoshinori Urakawa等。

catch—发文量

期刊论文>

论文:111 占比:98.23%

专利文献>

论文:2 占比:1.77%

总计:113篇

catch—发文趋势图

catch

-研究学者

  • Daisuke Funabara
  • Satoshi Kanoh
  • Yoshinori Urakawa
  • Justin Remais
  • 刘巍
  • 吴子松
  • 孟香
  • 朱建胜
  • 李铂
  • 毛勇
  • 期刊论文
  • 专利文献

搜索

排序:

年份

关键词

    • 汤琴琴
    • 摘要: catch这个词经常在棒球、篮球、板球等运动中听到,在这些运动中,球可能会被投掷和接住。然而,在动词短语中使用这个词,它的意思会发生巨大的变化,一起看看吧。Catch up赶上,了解到※To become aware of things that have happened recently.意识到最近发生的事情。I was able to catch up on what has occurred during the past few weeks by reading the newspaper.
    • Jay
    • 摘要: Reddish Egret棕颈鹭That fish is so cunning(狡猾的).Wait till I dry my feathers.I will catch you at all costs(不惜任何代价)then.Oh,it''s so cold!那条鱼真狡猾。等我先把羽毛晒干。无论付出什么代价我都要抓到你。噢,真冷啊!
    • 董佩希
    • 摘要: A man asked a farmer near a field,"Sorry sir,would you mind if I crossed your field instead of going around it?Yousee,I have to catch the 4:23 train."The farmer said,"Sure,go right ahead.And if my bull sees you,you’ll even catch the 4:11 one."
    • 董佩希
    • 摘要: A man asked a farmer near a field,"Sorry sir,would you mind if I crossed your field instead of going around it?You see,I have to catch the 4:23 train."The farmer said,"Sure,go right ahead.And if my bull sees you,you’ll even catch the 4:11 one."
    • 任珍; 冯贵龙; 樊凯; 闻伟敬; 张瑞; 傅圆伟; 张嘉利; 刘唯棕
    • 摘要: Objective To explore the applicability of the three commonly used CT examination decision rules in Chinese head injured children. Methods This prospective observational study included 1538 children and adolescents (aged < 18 years), who were treated at the Emergency Department of First Hospital of Shanxi Medical University after head injuries. The three clinical decision rules include the Children's Head Injury Algorithm for the Prediction of Important Clinical Events (CHALICE; UK); the prediction rule for the identification of children at very low risk of clinically important traumatic brain injury, that was developed by the Pediatric Emergency Care Applied Research Network (PECARN; USA), and the Canadian Assessment of Tomography for Childhood Head Injury (CATCH) rule. Diagnostic accuracy had been evaluated by using the rule-specific predictor variables to predict each rule-specific outcome measure in populations who met inclusion and exclusion criteria for each rule. Sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), and ROC curve were referred to the diagnostic accuracy. Indicators were characterized by 95% CI. Results Of the 1538 patients, CTs were obtained for 339 patients (22.04%). Forty-nine patients (3.19%) had positive CT results, 8 patients (0.52%) underwent neurosurgery, 2 patients (0.13%) died, and 1 patient (0.07%) may be missed. In this study, CHALICE was applied for 1394 children (90.70%; 95% CI: 89.24%-92.15%), PECARN for 801 children (52.11%; 95% CI: 49.62%-54.61%), and CATCH for 325 patients (21.15%; 95%CI: 19.10%-23.19%). The validation sensitivities of CHALICE, PECARN, and CATCH rules were 92.6%(74.2%-98.7%), 100% (56.1%-100%), and 85.7% (42.0%-99.2%), respectively; the specificities were 78.1%(75.7%-80.2%), 48.0% (44.5%-51.5%) and 70.8% (65.4%-75.6%); positive predictive value were 7.7% (5.1%-11.3%), 0.9% (0.4%-1.9%) and 6.1% (2.5%-13.2%); and negative predictive value were 99.8% (99.2%-100%), 99.1% (98.1%-99.6%), and 99.6% (97.2%-100%), respectively. Conclusions The clinical decision rules of CHALICE, PECARN and CATCH have high sensitivities. The specificity of PECARN rule is lower than those of CHALICE and CATCH rules. The above three clinical decision rules can be used for the decision of CT examination in Chinese children with head injury in practice.%目的 探讨国外常用的三种儿童头部外伤后CT检查决策规则在我国的适用性.方法 本前瞻性观察研究纳入了1538例因头部外伤就诊于山西医科大学第一医院急诊医学中心的未成年人(年龄<18岁).三种儿童头部外伤后CT检查决策规则包括:英国的儿童头部损伤重要临床事件预测算法(children's head injury algorithm for the prediction of important clinical events,CHALICE)、美国儿科急诊护理应用研究网研究的低风险颅脑损伤的头部外伤未成年人头颅CT检查的临床决策规则(paediatric emergency care applied research network,PECARN)以及加拿大儿童头部损伤断层扫描评估(Canadian assessment of tomography for childhood head injury,CATCH).本研究在满足各规则的纳入、排除标准的患者人群中,以各决策规则的观察结局作为金指标,评估上述三种规则预测变量的诊断准确性.诊断准确性指标评估包括:敏感性,特异性,阴性预测值(NPV),阳性预测值(PPV)和ROC曲线,以95%置信区间表示.结果 在1538例患儿中,共339例(22.04%)患儿接受了头颅CT扫描.其中,49例(3.19%)CT扫描阳性,8例(0.52%)患者接受了神经外科手术,2例患儿(0.13%)死亡,1例(0.07%)患儿可能被漏诊.本研究中,CHALICE适用于1394例患儿(90.70%,95%CI 89.24%~92.15%),PECARN适用于801例(52.11%,95%CI 49.62%~54.61%),CATCH则适用于325例患儿(21.15%,95%CI 19.10%~23.19%).CHALICE、PECARN、CATCH规则的敏感性分别为:92.6%(74.2~98.7)、100%(56.1~100)及85.7%(42.0~99.2);特异度分别是:78.1%(75.7~80.2)、48.0%(44.5~51.5)及70.8%(65.4~75.6);阳性预测值为:7.7%(5.1~11.3)、0.9%(0.4~1.9)及6.1%(2.5~13.2);阴性预测值为:99.8%(99.2~100)、99.1%(98.1~99.6)及99.6%(97.2~100).结论 CHALICE、PECARN、CATCH临床决策规则均具有高度敏感性,较CHALICE、CATCH规则而言,PECARN规则的特异度较低.
    • Daisuke Funabara; Yuuki Osakabe; Satoshi Kanoh
    • 摘要: Calponin is a basic actin-binding protein found widely in invertebrate tissues including catch muscle and therefore may participate in catch contraction. There is limited information about molluscan calponin and molecular characterization to reveal its function in the regulatory system. We previously identified and partially sequenced three calponin isoforms of the Japanese pearl oyster, Pinctada fucata (Pifuc-CP-1, Pifuc-CP-2 and Pifuc-CP-3). In this study, the full-length nucleotide sequences of the three isoforms were determined. The primary structures revealed that Pifuc-CP-1 consists of 324 amino acids (aa) with a molecular mass (Mw) of 34.7 kDa and an isoelectric point (pI) of 9.40. Pifuc-CP-2 is 303 aa in length with a Mw of 33.3 kDa and a pI of 9.30, and Pifuc-CP-3 is 398 aa in length with a Mw of 43.8 kDa and a pI of 8.55. Domain architecture prediction showed that the three isoforms have a single calponin homology (CH) domain and multiple calponin (CN) domains. Pifuc-CP-1, Pifuc-CP-2 and Pifuc-CP-3 possess four, three and five CN domains, respectively. Tissue distribution analysis indicated the presence of additional calponin isoforms and these isoforms are distributed widely in muscle and non-muscle tissues. Results of cDNA cloning revealed further four calponin isoforms: Pifuc-CP-4 (402 aa, 42.8 kDa, pI = 9.10), Pifuc-CP-5 (285 aa, 30.7 kDa, pI = 9.45), Pifuc-CP-6 (286 aa, 31.1 kDa, pI = 9.60) and Pifuc-CP-7 (302 aa, 33.3 kDa, pI = 9.10). The domain architecture of these four isoforms also consists of a single CH domain and multiple CN domains. Pifuc-CP-4 possesses six CN domains, whereas Pifuc-CP-5, Pifuc-CP-6 and Pifuc-CP-7 contain three CN domains. Sequence alignment of P. fucata calponin isoforms showed that Pifuc-CP-1, Pifuc-CP-2, Pifuc-CP-3 and Pifuc-CP-4 have identical CH domain sequences, whereas Pifuc-CP-5, Pifuc-CP-6 and Pifuc-CP-7 have identical CH domain sequences. The CN repeats were not well conserved. These findings suggest that P. fucata calponin isoforms function differently in each tissue.
    • Daisuke Funabara; Yuuki Nishimura; Satoshi Kanoh
    • 摘要: Molluscan smooth muscles, such as the bivalve adductor muscles and the mussel anterior byssus retractor muscles (ABRM), exhibit a unique contraction called “catch”. Catch contraction is regulated through twitchin phosphorylation and dephosphorylation. Twitchin from the ABRM of the Mediterranean mussel, Mytilus galloprovincialis, is phosphorylated by cAMP-dependent protein kinase (PKA), and PKA phosphorylation sites are located in both the N- and C-terminal regions of the twitchin molecule. The D2 site, which is adjacently located to the C-terminus, participates in forming a myosin, actin, and twitchin complex that is thought to contribute towards the maintenance of tension in the catch state. In contrast, although it has been reported to interact with thin-filaments, the molecular function of the region including the D1 site has remained largely unstudied. Three additional PKA consensus sequences were identified near the D1 site;however, it was not known if these sites could be directly phosphorylated by PKA. Here, we performed phosphorylation assays to identify phosphorylation sites near the D1 site using recombinant protein variants (TWD1-SSSS, TWD1-AAAS, TWD1-AASA, TWD1-ASAA, TWD1-SAAA, and TWD1-AAAA). All variants, except TWD1-AAAA (where all phosphorylatable serine residues were replaced by alanines), were phosphorylated by PKA. The four phosphorylation sites were named D1-1, D1-2, D1-3, and D1-4 (the originally identified D1) in order from the N-terminus. Phosphorylation assays using a 1/12.5 weight ratio of PKA to each TWD1 variant revealed that D1-4 was the most rapidly phosphorylated, closely followed by D1-1. However, D1-2 and D1-3 were phosphorylated at a lower level under equivalent conditions and were not phosphorylated when PKA was incubated with each TWD1 variant at a 1/100 weight ratio. Furthermore, we observed that TWD1-SSSS was phosphorylated in a stepwise fashion. These findings contribute towards the elucidation of the function of the twitchin D1 region in the regulatory system of catch contraction.
    • Daisuke Funabara; Ayaka Ohta; Jungo Sueyoshi; Satoshi Kanoh
    • 摘要: We determined the full-length primary structure of the tropomyosin (TM)-1 and -2 proteins from the adductor muscle of the Japanese pearl oyster Pinctada fucata (Pifuc-TM-1 and Pifuc-TM-2), and found that they are each composed of 284 amino acid residues. We predicted the gene structure of P. fucata TM (Pifuc-TM) using Splign alignment of our cDNA with genomic sequences and elucidated that Pifuc-TM consists of 10 exons. Exons 1 - 3 and 5 - 10 are used to transcribe Pifuc-TM-1 mRNA, and exons 1 - 4 and 6 - 10 are used to transcribe Pifuc-TM-2 mRNA. Both genes share the same start and stop codons located in exon 1 and exon 10, respectively. Using quantitative real-time PCR, we determined that the Pifuc-TM-1 gene was mainly expressed in adductor phasic muscle, and at a relatively weaker level in adductor catch muscle, whereas the Pifuc-TM-2 gene was expressed equally in both phasic and catch muscles. They were weakly expressed in gill and mantle. Immunoblot analysis using anti-Pifuc-TM-1 and anti-Pifuc-TM-2 antibodies revealed that adductor phasic muscle contained Pifuc-TM-1, while adductor catch muscle contained both Pifuc-TM-1 and Pifuc-TM-2. Differential scanning calorimetry (DSC) analysis was carried out for Pifuc-TM-1 and Pifuc-TM-2 expressed in bacteria, as well as TM purified from P. fucata phasic and catch muscle tissues (phasic-TM and catch-TM). The DSC data indicated that phasic-TM was mainly composed of Pifuc-TM-1, whereas catch-TM contained Pifuc-TM-1 and Pifuc-TM-2. These findings suggest that the distribution of Pifuc-TM-1 and Pifuc-TM-2 in adductor muscle is specific to the muscle fiber type, and reflects the properties of each.
    • Daisuke Funabara; Yoshinori Urakawa; Satoshi Kanoh
    • 摘要: Troponin is a complex of three proteins (troponin I, troponin C, and troponin T) that binds Ca2+ and is a thin filament-associated regulator of vertebrate striated muscle contraction. The function of troponin I (TnI) in vertebrates has been extensively characterized, but its role in molluscan muscles has not yet been elucidated. Our previous work suggested that the troponin C subunit has a role in adductor phasic muscle but not in catch muscle. Here, we investigated the molecular characteristics of TnI from the bivalve Japanese pearl oyster, Pinctada fucata to aid the elucidation of the function of molluscan muscle troponin. We determined the primary structure of the full-length TnI protein from the P. fucata adductor muscle (Pifuc-TnI) and found that it is composed of 286 amino acid residues with a predicted molecular weight of 33,737. Motif structure predictions and multiple sequence alignments revealed that Pifuc-TnI has a 138 residue extension at its N-terminus compared with rabbit TnI. This is analogous to characterized TnIs from other mollusks. However, unlike scallop TnI, Pifuc-TnI is predicted to contain two cAMP-dependent protein kinase phosphorylation sites, at residues 39 - 45 (RRGTEDD) and 145 - 151 (KKKSKRK). Phylogenetic analysis indicated that Pifuc-TnI and molluscan TnIs were grouped into the same clade. Pifuc-TnI gene structure predictions using Splign alignment of our obtained cDNA and genome sequences indicated that Pifuc-TnI consists of fifteen exons, with the start and stop codons located in exon 2 and exon 11, respectively. Using quantitative real-time PCR, we determined that the Pifuc-TnI gene is predominantly expressed in adductor phasic muscle, weakly in adductor catch muscle, and is not expressed in the gill, mantle or foot. These findings suggest that TnI, as a component of the troponin complex, plays a regulatory role in adductor phasic muscle contraction, but not in catch contraction.
    • 阳国兴; 杜光会; 高山; 李欢欢
    • 摘要: 目的 探讨和评估CATCH模式在住院患者跌倒安全管理中的临床效果及应用.方法 对我院2015年1月至2016年12月应用CATCH模式进行对跌倒风险进行全面、全程、全员参与的系统管理前后的跌倒上报事件的临床资料进行回顾性分析.其中2015年1月至2015年12月我院未应用 CATCH 模式进行系统管理收治患者总床日数为1399473例,2016年1月至2016年12月我院应用CATCH模式进行系统管理后收治患者总床日数为1411789例.分析应用CATCH模式的前后两组两组患者跌倒发生情况、特征及对于护理工作的满意程度.结果 与未应用CATCH模式进行对跌倒风险管理的2015年相比,2016年我院患者在住院期间跌倒数降低,差异具有统计学意义(P<0.05).同时,跌倒后造成总体伤害率较2015年显著降低(P<0.05),跌倒后1级伤害的发生率显著降低(P<0.05).同时,2016年患者对于护理工作的满意度明显更高(P<0.05).结论 以跌倒高危因素为切入点,以多学科合作、综合预防为核心,通过应用CATCH模式进行多学科合作的管理团队更为全面有效,该模式值得借鉴和推广.%Objective To investigate and evaluate the clinical effect and application of CATCH Model in the fall safety management of hospitalized patients.Methods A retrospective analysis was performed on the clinical data of fall incidents repor-ted before and after the comprehensive,whole-process and full-participation systematic management of fall risk used the CATCH model from January 2015 to December 2016 in our hospital.Among them,the total number of patients admitted was 1399473,from January 2015 to December 2015,who did not apply CATCH model for systematic management. The number of patients was 1411789,from January 2016 to December 2016,who were used CATCH model for systematic management.To analyze the fall inci-dence,characteristics and satisfaction of nursing care of two groups before and after the application of CATCH model.Results Compared with 2015 without fall risk management using CATCH model,the fall incidences of hospitalized patients in 2016 was low-er than that in 2015,the difference was statistically significant(P<0.05).At the same time,the overall injury rate after the fall had a significant decrease from 2015(P<0.05),and the incidence rate of the first grade injury after the fall was significantly lower (P<0.05).At the same time,patients' satisfaction with nursing care was significantly higher in 2016(P<0.05).Conclusion Taking the high risk of falling as the starting point,the multidisciplinary cooperation and integrated prevention as the core,the man-agement team through multidisciplinary cooperation using the CATCH model is more comprehensive and effective,which is worth learning from and popularizing.
  • 查看更多

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号