抗衰老药
抗衰老药的相关文献在1984年到2017年内共计189篇,主要集中在中国医学、药学、预防医学、卫生学
等领域,其中期刊论文188篇、会议论文1篇、专利文献72030篇;相关期刊124种,包括医药与保健、福建中医药、光明中医等;
相关会议1种,包括中国科协首届学术年会等;抗衰老药的相关文献由302位作者贡献,包括张小如、王正引、许士凯等。
抗衰老药—发文量
专利文献>
论文:72030篇
占比:99.74%
总计:72219篇
抗衰老药
-研究学者
- 张小如
- 王正引
- 许士凯
- 兰风华
- 吴晓平
- 瞿延晖
- 丁克祥
- 何忠效
- 侯士良
- 傅福英
- 吴志奎
- 周林瑛
- 塞冬
- 巩平
- 张克纯
- 徐桂香
- 徐远祥
- 戴裕光
- 文润玲
- 文清
- 施红
- 李仁俊
- 杨国汉
- 林一萍
- 王文智
- 王晓明
- 白坚石
- 陈勤
- 陈清江
- 黄可泰
- 一凡
- 于娜
- 于正菊
- 任玉启
- 何淑红
- 何满
- 佘敏
- 佟彤
- 侯荣先
- 傅文庆
- 傅薇
- 冯彪
- 冯文宇
- 冯春雷
- 冯芸
- 冯芹喜
- 刘传珍
- 刘光谱
- 刘国应
- 刘天填
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沈羡云
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摘要:
古往今来,人们追寻长寿的脚步从未停歇。2000多年前,秦始皇派遣方士徐福带着3000名童男童女出海去寻找长生不老药,但到死也没有等到他们回来。雍正皇帝也想通过炼丹来得到长寿,结果最后死于汞中毒。将近100年前,斯大林期待博戈莫列茨院士研究出长寿秘方,并对他百般支持,结果博戈莫列茨院士于65岁去世,斯大林只能苦笑:“这家伙把大家都骗了。”由此,在人们的心目中,长寿药是可望不可及的,是骗人的。但是,
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王晶;
黄勇;
李海龙;
林志艳;
田一虹;
陈彻
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摘要:
Objective To explore the effects of aqueous extracts of Codonopsis Radix onD-galactose induced aging model mice; To discuss the anti-aging molecular mechanism of Codonopsis Radix.Methods Subcutaneous injection ofD-galactose solution was used to establish aging models. 100 Kunming mice were divided into normal control group, model group and low-, medium-, high-dose of Codonopsis Radix interventional groups randomly, 20 mice in each group. Low-, medium-, high-dose of Codonopsis Radix interventional groups were given relevant dosage for gavage, while normal control group and model group were given the same volume of NS by gavage for 42 d. After treatment for 42 days, the BUN and CREA in mouse serum were examined; the AffymetrixmiRNA 4.0 microarray was employed to identify the differentially expressed microRNA (miRNA) related with these processes; the bioinformatic tools were also used to further analyze the cluster of miRNA microarrys and the pathways which the target genes of miRNA were involved in.Results Compared with normal control group, the levels of BUN and CREA in mouse serum increased in model group (P<0.05); compared with model group, the levels of BUN and CREA in Low-, medium-, high-dose of Codonopsis Radix interventional groups decreased, in which high-dose of Codonopsis Radix could most significantly inhibit the level of BUN (P<0.05); the cluster analysis showed the miRNA expression profilings of high dose of Codonopsis Radix interventional group and normal control group were brought together, while the profiling of model group was clearly divided with the other groups. In model group vers normal control group, 36 differentiated expressed miRNA showed, which predicated in 10 main biological functions. In high-dose of Codonopsis Radix interventional group vers model group, 34 differentiated expressed miRNAs in high-dose of Codonopsis Radix interventional group showed, and the analytical results of biological functions of target genes were the same as those of model group vers normal control group.Conclusion In the anti-aging process, Codonopsis Radix can not only influence the miRNA expression profiling, but also influence its functional environment.%目的:观察党参水提物对衰老模型小鼠肾组织microRNA(miRNA)表达谱的影响,探讨党参抗衰老的分子机制。方法采用皮下注射D-半乳糖溶液制造衰老模型。将100只昆明种小鼠随机分为正常组、模型组和党参低、中、高剂量组,每组20只。党参各组给予相应剂量党参水煎液灌胃干预,正常组和模型组给予等量生理盐水灌胃,连续42 d。生化分析仪测定小鼠血清尿素(BUN)和肌酐(CREA)含量;利用AffymetrixmiRNA 4.0微阵列芯片筛选D-半乳糖致小鼠衰老和党参干预衰老过程中差异表达的miRNA,并利用生物信息学工具对芯片结果进行聚类及信号通路分析。结果与正常组比较,模型组小鼠血清BUN和CREA含量显著升高(P<0.05);与模型组比较,党参各剂量组小鼠血清BUN和CREA含量呈下降趋势,其中党参高剂量组BUN下降较显著(P<0.05);芯片聚类分析显示,模型组miRNA表达谱与正常组和党参高剂量组明显分开,而党参高剂量组和正常组miRNA表达谱聚在一起;另外,模型组比正常组有36个差异表达miRNA,其靶基因参与到10个主要的生物学功能中;党参高剂量组比模型组有34个差异表达miRNA,其靶基因的生物学功能分析与模型组比正常组的分析结果相同。结论在抗衰老过程中,党参不仅影响了miRNA表达谱的变化,也影响了其作用的功能环境。
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一凡;
思佳
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摘要:
健康吃对食物,预防器官衰老美国一家健康杂志最新载文称,人体器官衰老程度不同,不同饮食其实就是它们的"抗衰老药"。绿叶菜让大脑年轻5岁。25岁之后,人的大脑每10年会萎缩2%。每天吃蔬菜(尤其是绿叶蔬菜)两份以上,可以使人的注意力相当于年轻5岁的状态。健康吃对食物,预防器官衰老
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摘要:
据报道,欧洲科学家将于2011年底在欧洲各地推出一项血液测试,声称能通过测试染色体末端的"端粒",测出人类寿命长短,仅需花费500欧元(约合人民币4611元)。但这项测试引发伦理方面的争议。
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