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恒磁场

恒磁场的相关文献在1975年到2021年内共计132篇,主要集中在基础医学、临床医学、内科学 等领域,其中期刊论文72篇、会议论文4篇、专利文献39173篇;相关期刊45种,包括现代生物医学进展、中国生物医学工程学报、中国医学物理学杂志等; 相关会议4种,包括第二届中国西部磁材论坛暨粘结磁体制作与应用技术研讨会、第七次全国心血管病学术会议、中国生物医学工程学会第五次全国学术大会暨IEEE/EMBS第20次国际学术年会等;恒磁场的相关文献由315位作者贡献,包括张荣庆、贾国良、王海昌等。

恒磁场—发文量

期刊论文>

论文:72 占比:0.18%

会议论文>

论文:4 占比:0.01%

专利文献>

论文:39173 占比:99.81%

总计:39249篇

恒磁场—发文趋势图

恒磁场

-研究学者

  • 张荣庆
  • 贾国良
  • 王海昌
  • 程何祥
  • 周廉
  • 李争显
  • 赵新国
  • 夏乙予
  • 廖晓玲
  • 徐文峰
  • 期刊论文
  • 会议论文
  • 专利文献

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    • 刘仕琪; 吕毅
    • 摘要: 对儿童先天性食管闭锁和肛门直肠闭锁畸形的消化道吻合,可以通过磁体压榨作用使组织坏死并形成黏浆膜、肌层对位,从而愈合形成牢固的吻合口.利用恒磁场的作用力实现对先天性食管闭锁和肛门直肠闭锁畸形微创治疗是一种可靠可行的方法.%Magnetic compression causing serosa-to-serosa apposition after pressure necrosis has been confirmed to create solid anastomostic connections for congenital esophageal atresia and rectal atresia in children .And translumenal digestive tract anastomosis using constant magnetic field as a mini-invasive technique is both reliable and feasible for congenital esophageal and anorectal abnormalities .
    • 唐奇
    • 摘要: 设计一种基于IGBT元件的频率可调的恒磁场脱磁器.阐述恒磁场脱磁器的结构与原理,详细介绍逻辑控制、电路、电源控制部分的设计及功能.该脱磁器结构简单、可靠性高、易于维护,可广泛应用于各种需要脱磁的工作现场.
    • 唐利涛; 李刚; 杨舟; 蒋雯倩
    • 摘要: 为了提高电子式电能表的磁屏蔽效能,确保电能计量的准确、可靠和安全,需要准确检定电能表屏蔽恒定磁场效果.针对目前电能表屏蔽恒定磁场效果的检定方法的不足,对电磁铁磁场和空气气隙磁场进行分析,得到类似永磁体的磁场发生源装置,基于此建立了电子式电能表防恒定磁场干扰评估系统.实际应用效果表明,该评估系统能准确检定电能表抗恒定磁场的干扰能力.评估系统的研发与应用为检定电能表的屏磁蔽效能提供了可靠、有效的方法.
    • 刘少俊; 王晓艳; 肖志明; 唐岸柳; 唐五良; 沈守荣
    • 摘要: 目的:评价体外恒磁场作用下,双标记干细胞经外周静脉、门静脉、肝动脉移植在损伤肝脏中的定植率及治疗急性肝损伤的有效性.方法:分离骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSCs),经培养传代纯化、体外诱导,分化为肝样细胞,绿色荧光蛋白(green fluorescent protein,GFP)和菲立磁(Feridex)体外双标记BMSCs,不同途径移植双标记BMSCs至肝脏,于移植后第1,2,3,4周处死大鼠,测定血清丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)、白蛋白(ALB)水平,并取肝组织做苏木精-伊红染色(HE染色)、荧光显微镜下观察肝内GFP阳性率.结果:双标记BMSCs通过尾静脉、门静脉、肝动脉3种途径及其外加恒磁场作用下,移植后第4周均能定植于肝脏,改善肝功能;在远期疗效不变的前提下,肝门静脉移植+恒磁场组、肝动脉移植+恒磁场组促进肝功能的早期恢复.结论:BMSCs移植可有效治疗急性肝损伤,首选经门静脉+恒磁场、肝动脉+恒磁场途径,次选外周静脉或外周静脉+恒磁场途径.
    • 陈晨; 王晋; 谢学军; 穆士杰; 张献清; 安群星
    • 摘要: 目的:研究恒磁场对心肌梗死大鼠骨髓间充质干细胞(bone marrow-derived mesenchymal stem cells,BMSCs)移植后心脏功能的影响.方法:取180g,9-12周龄雄性SD大鼠骨髓,以密度梯度离心分离出单个核细胞(MNCs),于体外培养并传代培养出骨髓间充质干细胞(MSCs).制作大鼠心肌梗死模型,将1.5× 106 BMSCs注射入梗死梗死区周围,分为磁场照射+BMSCs植入组、BMSCs植入组及空白对照组.4周后处死动物,每组5只大鼠.磁场照射组用0.4 T恒磁场置于心前区30 min,每日1次,共7天.用颈动脉插管法测定心脏功能,Masson三色染色测定梗死面积,VWF Ⅷ染色计算血管密度.结果:与对照组相比BMSCs组以及磁场组均可以显著提高左心室收缩压(LVSP),dp/dtmax以及-dp/dtmax,减少LVEDP (P<0.05).但是,磁场组与BMSCs组相比LVSP,左心室内压最大上升速率(dp/dtmax)以及左心室内压最大下降速率(-dp/dtmax)增高,左心室舒张末压(LVEDP)减少(P<0.05).与对照组相比BMSCs组以及磁场组均可以显著提高减少心梗面积(P<0.05).磁场组与BMSCs组相比心梗面积减少(P<0.05).与对照组相比BMSCs组以及磁场组均可以显著提高增加血管密度(P<0.05).磁场组与BMSCs组相比血管密度增加(P<0.05).结论:恒磁场具有加强移植BMSCs改善心脏功能的作用.%Objective: To investigate the effect of constant magnetic fields exprose on BMSCs which transplante into infarcted myocardium. Methods: Mononuclear cells were isolated from 180g ,9-12 weeks male SD rat bone marrow by density-gradient centrifugation and were cultured on fibronectin-coated plates with bovine pituitary extract. Infarct size, density of capillary and cardiac function was evaluated after BMSCs transplantation into infarcted myocardium in different groups. Results: Compared with that in the control group, both magnetic fields group and BMSCs groups had significant improvement on hemodynamic parameters (LVSP, LVEDP, +dP/dtmax and -dP/dtmin). Both magnetic fields group and BMSCs groups treated MI animals showed smaller infarction size compared with that in the control animals. Capillary density increased in magnetic fields group and BMSCs groups compared with that in control treated hearts with MI. Conclusion: Constant magnetic field enhance rat bone marrow mesenchymal stem cells improve cardiac function post myocardial infarction.
    • 聂志勇; 邢柏春; 李耀明; 高操; 李飞江; 保庭毅
    • 摘要: 目的:研究300mT恒磁作用对于糖尿病大鼠皮肤创伤愈合的修复效果,旨在为其系统的临床应用提供理论依据.方法:8周龄雌性SD大鼠,体重220±20g,行腹腔注射50mg/kg链脲做菌素,3天后空腹血糖高于16.7 mmol/L的大鼠用于实验.32只糖尿大鼠病和16只正常大鼠的背部构建直径2cm的圆形创口,将动物随机分为对照组、糖尿病组、糖尿病恒磁场作用组,每组16只,术后一天采用无菌纱布将创口进行包裹,磁场作用组的纱布表面粘附有300 mT中心场强的钕铁硼恒磁片.分别于第6、13、20天每组处死4只大鼠,对其进行创伤愈合率和创伤表皮组织生物力学实验评估.结果:相比于糖尿病组,糖尿病恒磁场治疗大鼠的伤口愈合速度在第6、13、20天显著提高(P<0.05),伤口组织的抗张强度亦显著提升(P<0.05),其愈合速度接近于正常状态下的大鼠.结论:300mT恒磁场作用对于促进糖尿病大鼠皮肤创伤的愈合速率具有积极的治疗作用,恒磁场治疗凭借经济、简单、方便等特点,具有广阔的临床应用前景.%Objective:To investigate the inhibitive effects of static magnetic fields (SMF) with 300 mT intensity on diabetes-induced epidermal wound healing in rats,and to provide the important experimental basis for the clinical application of static magnetic fields.Methods:Eight-week old female Sprague-Dawley (SD) rats with 220 ± 20 g body weight were given single intravenous administration of streptozotocin (STZ) at a dose of 50 mg/kg versus body weight.Animals with fasting blood glucose concentration higher than 16.7 mmol/L were employed in the following experiment.One open circular wound with 2 cm diameter in the dorsum was generated on either normal or diabetic mice and then covered with sterile gauzes 1 day post surgery.Sixteen normal mice were used as the Control group,and 32 diabetic mice were randomly divided into Diabetes and SMF treatment group.The rats in SMF treatment group were exposed to SMF by gluing one magnetic disk with 300 mT intensity.On days 6,13 and 20,four rats in each group were euthanized,and the gross wound area and the tensile strength of the soft tissue were respectively qualified.Results:Compared with that in the Diabetes group,diabetic rats under SMF exposure demonstrated significantly accelerated process in the epidermal wound healing (P<0.05),as well as dramatically higher tissue tensile strength (P<0.05) at day 6,13 and 20.The wound recovery process of diabetic rats under SMF exposure was close to that of rats in the control group.Conclusion:SMF with 300 mT has the capacity of remarkably accelerating the diabetic wound healing process in rats.SMF treatment,as an economic,easy and convenient method,possesses bright application potential in clinics for promoting diabetic wound healing.
    • 陈晨; 王晋; 谢学军; 穆士杰; 张献清; 安群星
    • 摘要: Objective: To investigate the influence of constant magnetic fields on the apoptosis of marrow-derived mesenchymal stem cells under hypoxia and serum deprivation condition and further to explore its mechanism. Methods:Mononuclear cells were isolated from rat bone marrow by density-gradient centrifugation and then they were cultured on fibronectin-coated plates supplied with bovine pituitary extract to get MSCs. BMSCs were identified by Morphology and Surface molecule marker analyzed by FCM. Then the marrow-derived mesenchymal stem cells were cultured under hypoxia and serum deprivation condition (hypoxia and SD), the proportion of apoptosis and the level of p-Akt in different groups were detected by tunnel analysis and Western bolt respectively. Results: (1)The marrow-derived mesenchymal stem cells were successfully obtained by identification of morphology and the MSCs specific surface marker. (2) The proportion of apoptosis is significantly higher in the group under hypoxia and SD than that of group under constant magnetic fields plus hypoxia and SD. The level of p-Akt upgraded significantly, therefore indicated the activation of PI3K/Akt pathway (P?0.05). Conclusion:Constant magnetic field inhibited the apoptosis of marrow-derived mesenchymal stem cells under hypoxia and SD by activating PDK/Akt.%目的:研究恒磁场对体外缺血缺氧培养条件下大鼠骨髓间充质干细胞(Bone marrow-derived mesenchymal stem cells,BMSCs) 凋亡的影响并探讨其作用机制.方法:采取大鼠骨髓,以密度梯度离心分离出单个核细胞(MNCs),于体外培养并由牛垂体提取物(PEX)诱导扩增传代培养出骨髓间充质干细胞(MSCs).经形态学和流式细胞仪检测MSCs表面标志物鉴定后,将骨髓间充质干细胞(BMSCs)在缺血缺氧条件下培养,通过TUNEL检测比较不同组别细胞的凋亡率和蛋白印迹法(western blot)来观察细胞中特定蛋白质的变化.结果:①经形态学观察和流式细胞仪检测MSCs表面标志物鉴定,提示骨髓间充质干细胞培养成功.②缺血/缺氧组与缺血/缺氧+磁场组比较,缺血缺氧组的凋亡率显著性增加,Akt磷酸化水平显著上升(P<0.05).提示恒磁场可以使PI3K(Phosphoinositide-3kinase)/Akt(ProteinkinaseB,PKB)信号通路被激活而抑制凋亡的发生.结论:恒磁场通过激活PI3K/Akt信号通路抑制体外缺血缺氧条件下培养的骨髓间充质干细胞的凋亡.
    • 张杰; 陆洪英; 金成文; 成敏
    • 摘要: 目的 观察不同强度的恒磁场作用不同时间对培养的人脐静脉内皮细胞(HUVECs)增殖、凋亡及分泌功能的影响.方法 将HUVECs分别暴露于场强为5、22、86或135 mT的恒磁场中,磁场作用时间分别为8、12或24 h.以流式细胞技术分析恒磁场对HUVECs增殖及凋亡的影响;比色法测定细胞培养液中一氧化氮(NO)含量的变化;放射免疫法测定细胞培养液中的内皮素-1( ET-1)及6-酮-前列环素F1α(6-keto-PGF1α)的含量.结果 ①低强度磁场(5 mT)短时间(8 h)作用于HUVECs可促使其增殖,但高强度磁场( 135 mT)或作用时间过长(12 h或24 h)则会抑制HUVECs的增殖;②磁场对HUVECs凋亡无影响;③低强度磁场(5 mT)短时间(8 h)作用可促使HUVECs合成释放NO和6-keto-PGF1α,但高强度磁场( 135 mT)或作用时间过长(12 h或24 h)则会抑制HUVECs合成分泌NO和6-keto-PGF1α;④细胞暴露于磁场8h时,5 mT组和22 mT组与对照组比较,HUVECs合成释放ET-1量无明显变化(P>0.05),但86 mT组和135 mT组的细胞ET-1分泌量高于对照组(P<0.01).当磁场作用时间分别为12和24 h时,5 mT组与对应时间点对照组比较,细胞ET-1合成释放量仍无变化(P>0.05),22 mT组、86 mT组、135 mT组则明显低于对照组(P<0.01).结论 低强度磁场、短时间作用可促进HUVECs的增殖及舒血管物质的合成分泌,而高强度磁场或磁场作用时间过长则抑制HUVECs增殖,增加缩血管物质的合成.%Objective To evaluate the effects of static magnetic fields (SMFs) of different intensity and exposure duration on the proliferation and apoptosis of human umbilical cord endothelial cells (HUVECs),and their release of nitric oxide (NO),6-keto-prostacyclin 1α (6-keto-PGF1α) and endothelin (ET-1).Methods Cultured HUVECs were exposed to a SMF at 5,22,86 or 135 mT for 8,12 or 24 hours.Their proliferation and apoptosis were monitored by flow cytometry (FCM).The medium was collected to test its NO content by optical density.ET-1 and 6-keto-PGF1α were measured by radioimmunization.Results ( 1 ) The proliferation of HUVECs increased when the cells were exposed to a SMF at 5 mT for 8 h,but a SMF at 135 mT for 12 h or 24 h inhibited the proliferation of HUVECs.(2)An SMF had no effect on apoptosis of HUVECs.(3)An SMF at 5 mT for 8 h increased the release of NO and 6-keto-PGF1 a,but the release of NO and 6-keto-PGF1 a decreased when the SMF intensity was 135 mT or the cells were exposed to an SMF for 12 h or 24 h.(4) An SMF at 5 mT or 22 mT for 8 h did not effect the release of ET-1.An SMF at 86 mT or 135 mT increased the release of ET-1.Compared with a control group,an SMF at 5 mT for 12 or 24 h did not affect the release of ET1,but at 22,80 or 135 mT,the release of ET-1 decreased significantly.Conclusions Exposure to a low intensity SMF for a short duration could improve the proliferation of HUVECs and increase the release of vasoactive factors,but if HUVECs are exposed to a strong SMF or exposed for a long duration,the proliferation and the release of vasoactive factors is decreased.
    • 巴清伟
    • 摘要: 随着我国选矿工艺和技术的不断进步,选厂对矿浆的脱磁要求越来越高,抚顺隆基电磁科技有限公司研制开发出了基于大功率IGBT的LTC系列恒磁场脱磁器,介绍了LTC系列恒磁场脱磁器的设计原理、主要特点及应用情况.
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