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    • Satyavarapu Naga Parameswara Gupta
    • 摘要: In this paper we will see the model of Universe according to Dynamic Universe Model of Cosmology by visualizing various processes that are happening in the Universe as per experimental evidences. For simplifying the matter here, we will see in part 1: about the Galaxy life cycle, where the birth and death of Galaxies discussed. Probably Universe gives guidance for the movement of Galaxies. We call this Part 1: Thinking and Reproducing Universe or Mindless Universe? (Galaxy life cycle). We see every day Sun, Stars, Galaxies etc., dissipating enormous energy in the form of radiation by the way of fusion of Hydrogen to helium. So after sometime all the Hydrogen is spent and Universe will die, is it not? … Dynamic Universe Model says that the energy in the form of electromagnetic radiation passing grazingly near any gravitating mass changes in frequency and finally will convert into neutrinos (mass). Hence Dynamic Universe Model proposes another process where energy will be converted back into matter and the cycle energy to mass to energy continues, sustaining the Universe to maintain this present status for ever in this form something like a Steady state model without any expansion. This we will see in Part 2: Energy - Mass - Energy Cycle. After converting energy into mass “how various elements are formed and where they are formed?” will be next logical question. Dynamic Universe Model says that these various particles change into higher massive particles or may get bombarded into stars or planets and various elements are formed. Here we bifurcate the formation of elements into 6 processes. They are for Elementary particles and elements generated in frequency changing process, By Cosmic rays, By Small stars, By Large Stars, By Super Novae and Manmade elements By Neutron Stars. This we will discuss in Part 3: Nucleosynthesis.
    • Katharina Renner-Martin; Norbert Brunner; Manfred Kühleitner; Werner-Georg Nowak; Klaus Scheicher
    • 摘要: The paper searched for raw data about wild-caught fish, where a sigmoidal growth function described the mass growth significantly better than non-sigmoidal functions. Specifically, von Bertalanffy’s sigmoidal growth function (metabolic exponent-pair a = 2/3, b = 1) was compared with unbounded linear growth and with bounded exponential growth using the Akaike information criterion. Thereby the maximum likelihood fits were compared, assuming a lognormal distribution of mass (i.e. a higher variance for heavier animals). Starting from 70+ size-at-age data, the paper focused on 15 data coming from large datasets. Of them, six data with 400 - 20,000 data-points were suitable for sigmoidal growth modeling. For these, a custom-made optimization tool identified the best fitting growth function from the general von Bertalanffy-Pütter class of models. This class generalizes the well-known models of Verhulst (logistic growth), Gompertz and von Bertalanffy. Whereas the best-fitting models varied widely, their exponent-pairs displayed a remarkable pattern, as their difference was close to 1/3 (example: von Bertalanffy exponent-pair). This defined a new class of models, for which the paper provided a biological motivation that relates growth to food consumption.
    • Guomin Li; Zhuo Li; Xiangzhong Ren; Yan Zhang; Zhiwen Chen; Jianqiang Yu
    • 摘要: The hierarchical structure can significantly improve the diffusion efficiency of the catalyst and regulate the product distribution. Therefore, the preparation of hierarchical SAPO-34 molecular sieve has been a hot research topic. With Cetyltrimethyl Ammonium Bromide (CTAB) and Diethylamine (DEA) as templates, a two-step crystallization process was employed to synthesize hierarchical SAPO-34 molecular sieves. We found that the aging process is vital for the formation of pure phase SAPO-34. It was investigated the relationship of crystallinity trend and mesoporous content with the crystallization time. The results showed that the prolongation of crystallization time was beneficial to enhance the crystallinity of the molecular sieve, but unfavourable to the retention of mesoporous structure. The formation process of hierarchical SAPO-34 molecular sieve involved agglomeration, disintegration, crystallization, re-agglomeration and growth. The hierarchical SAPO-34 molecular sieve with a satisfactory crystallinity and considerable mesoporous structure could be obtained after 36 hours of crystallization. Moreover, the sample had the most suitable acid strength as well as acid amount. The catalytic activity was investigated by catalytic dimethyl ether (DME) to olefin (DTO) reaction. It revealed that the conversion of DME and the selectivity to olefins over the hierarchical SAPO-34 molecular sieve were significantly enhanced with comparison to that over microporous SAPO-34 molecular sieve. The amount of coke deposition of the hierarchical SAPO-34 molecular sieve (14.2%) was lower than that over the microporous molecular sieve (16.5%). Meanwhile, the propylene selectivity of hierarchical SAPO-34 was higher than that of microporous SAPO-34 in the whole reaction. In a word, the hierarchical SAPO-34 molecular sieve synthesized in this study showed a longer catalytic life, higher coke deposition resistance and higher propylene selectivity.
    • Mitsuaki Nagata
    • 摘要: We have inquired into a means to decrease the number of charged particles escaping from a loss cone of a magnetic mirror reactor as many as possible. We previously reported the way of installing a supplemental magnetic mirror (which has a cyclotron heating space within) at the exit of a main magnetic bottle. The cyclotron heating space was set to increase a reflection-efficiency of the supplemental mirror. We could not suppress the loss of the escaping deuteron ions sufficiently even with a very long mirror and a very powerful electric field. Then, in this work we propose a new plan of installing another supplemental mirror besides the previous supplemental mirror. A new mirror is set perpendicularly to the center axis of the main bottle. By the addition of the perpendicular mirror, an efficiency of sending back of escaping deuteron ions is considerably theoretically improved. Also in the previous work, since we did not touch how to supply a high-frequency electric field to the cyclotron heating space, here we consider supplying it by an extraordinary-wave with a cyclotron frequency. It is mentioned that propagation of an extraordinary-wave with an electron cyclotron frequency depends on a magnetic field strength and density of escaping electrons.
    • 邱臻
    • 摘要: 诗歌翻译是一个十分具有争议的话题,许多人甚至认为诗歌是无法翻译的。诗歌所带给人的美感无论是从其意境层面还是其诵读时的音乐性,都是由某一特定的语言造就的,因而诗歌的美学要素很难在字句的转化中体现出来,更贴切地说,诗歌翻译是一种基于对原文美学理解欣赏之上的再创作行为。
    • Do Tan Si
    • 摘要: Finding that in the formula of expansion of a function into a series of wave-like functions ?the coefficients are its Fourier transforms, if existed, we deduce mathematically all the principles and hypothesis that illustrated physicists utilized to build quantum mechanics a century ago, beginning with the duality particle-wave principle of Planck and including the Schrödinger equations. By the way, we find a simple Fourier transform relation between Dirac momentum and position bras and a useful permutation relation between operators in phase and Hilbert spaces. Moreover, from the found particle-wave duality formula we prove and obtain again essentially by mathematical analysis all the laws of wave optics concerning reflections, refractions, polarizations, diffractions by one or many identical 3D objects with various forms and dimensions.
    • Agripina Shitandayi; Francis Orata; Fred Lisouza
    • 摘要: Continuous concerns about Polycyclic Aromatic Hydrocarbons (PAHs) presence in the environment have raised concern because of their toxic effects to various organisms. Sugarcane farming and cane processing industries are major economic activities within River Nzoia catchment area in Kenya. For instance, the sugar industries produce wastes and by products which can cause PAHs emission and environmental contamination in addition to activities related to rapid urbanization that is being observed within the catchment. This study presents a report on sources and distribution of PAHs levels in sugarcane by products waste, sediments, water and soils within the River Nzoia catchment area. Soil and sediment samples were extracted by soxhlet extraction using dichloro-methane and with C-18 catridges. Analyte separation and identification was done by GC-MS. Fourteen PAHs were detected with concentration ranges of;0.6 μg/L - 80 μg/L for water, 0.01 μg/kg - 1200 μg/kg for soils and 0.13 μg/kg - 19.6 μg/kg for sediments. Bagasse waste had PAHs concentrations in the range of 0.4 - 14 μg/kg, and filter cake in the range of 1.7 - 30 μg/kg. Boiler waters reported the presence of 8 PAHs. The ratio of concentrations of PAHs in boiler water, filter cake and bagasse waste to the soils and water samples within the vicinity to the sugar processing companies did not indicate a point source of contamination;rather it pointed to diffuse sources. The same results were observed for water and sediment samples obtained in the vicinity of waste dumpsite. Variation of PAHs concentrations from sugar manufacturing processes corresponded to the kind and conditions of the processes. Lower molecular weight PAHs dominated in water sample. The presense of benz: 1) pyrene, benz 2) flourancene and Indeno(123,cd)pyrene in both water and sludge soils are of concern since this water is abstracted for domestic use, while sludge soil is used as fertilizer in agricultural farms. Although the levels of PAHs obtained in this study were below the established environment and human health safefty limits, the results underscore the need for mornitoring levels and determining potential sources for PAHs in the environment.
    • Jirapong Jairin; Phanchita Vejchasarn; Thanapa Somjai; Kanuengnij Srivilai; Kulchana Darwell; Phikul Leelagud; Rungnapa Kawichai; Jate Kotcharerk; Arissara Suthanthangjai; Nattaya Popa; Suphalaksana Lachanthuek; Varapong Chamarerk
    • 摘要: Rice is the most significant global food security. Several biotic factors limit rice production, breeding biotic-resistant rice has, therefore, become an increasingly important goal. Two elite rice lines, IR71033-121-15 (IR71033) and IR57514-PMI-5-B-1-2 (IR57514), provide potential genes for biotic stress resistance traits. In this study, genotyping by sequencing (GBS) for single nucleotide polymorphism (SNP)-based linkage map construction was used to detect quantitative trait loci (QTLs) for blast (BL), bacterial blight (BB), whitebacked planthopper (WBPH), and brown planthopper (BPH) resistance. IR71033 was derived from Oryza minuta and carried BL, BB, WBPH, and BPH resistance QTLs. IR57514 is a well-adapted rainfed lowland line that carries BL and BB resistance QTLs. Two sets of recombinant inbred line (RIL) populations derived from crosses of KDML105 × IR71033 and KDML105 × IR57514 were used to dissect the genetic basis of disease and insect pest resistance. The RIL populations were evaluated for BL, BB, WBPH, and BPH resistance from 2016 to 2018 at four rice research centers in Thailand. From these, we identified a large number of SNPs through GBS and constructed high-resolution linkage maps. By combining phenotypic evaluation with the GBS data, a total of 24 QTLs on four chromosomes were detected that confered pest resistance and explained 7.3% - 61.4% of the phenotypic variance. These findings should facilitate identifying novel resistance genes and applying marker-assisted selection for resistance to the four major rice pests investigated here. These strategies will improve the resilience and reliability of rice varieties adapted to the low-yielding environment of rainfed lowland areas worldwide.
    • Qi-Feng Chen; Wang Li; Pei-Hong Wu; Lu-Jun Shen; Zi-Lin Huang
    • 摘要: BACKGROUND Hepatitis B virus (HBV) has been recognized as a leading cause of hepatocellular carcinoma (HCC). Numerous reports suggest that immune infiltration can predict the prognosis of HCC. Nonetheless, no creditable markers for prognosis of HBV-related HCC have been established by systematically assessing the immune-related markers based on tumor transcriptomes. AIM To establish an immune-related marker based on the cell compositions of immune infiltrate obtained based on tumor transcriptomes, so as to enhance the prediction accuracy of HBV-related HCC prognosis. METHODS RNA expression patterns as well as the relevant clinical data of HCC patients were obtained from The Cancer Genome Atlas. Twenty-two immunocyte fraction types were estimated by cell type identification by estimating relative subsets of RNA transcripts. Subsequently, the least absolute shrinkage and selection operator (LASSO) Cox regression model was employed to construct an immunoscore based on the immunocyte fraction types. Afterwards, the receiver operating characteristic (ROC) curve, Kaplan-Meier, and multivariate Cox analyses were performed. Additionally, a nomogram for prognosis that integrated the immunoscore as well as the clinical features was established. Meanwhile, the correlation of immunoscore with immune genes was also detected, and gene set enrichment analysis (GSEA) of the immunoscore was conducted. RESULTS A total of 22 immunocyte fraction types were predicted and compared among the tumor as well as non-tumor samples. An immunoscore was constructed through adopting the LASSO model, which contained eight immunocyte fraction types. Meanwhile, the areas under the ROC curves for the immunoscore biomarker prognostic model were 0.971, 0.912, and 0.975 for 1-, 3-, and 5-year overall survival (OS), respectively. Difference in OS between the high-immunoscore group and the low-immunoscore group was statistically significant [hazard ratio (HR)= 66.007, 95% confidence interval (CI): 8.361-521.105;P < 0.0001]. Moreover, multivariable analysis showed that the immunoscore was an independent factor for predicting the prognosis (HR = 2.997, 95%CI: 1.737-5.170). A nomogram was established, and the C-index was 0.757 (95%CI: 0.648-0.866). The immunoscore showed a significant negative correlation with the expression of PD-1 (P = 0.024), PD-L1 (P = 0.026), PD-L2 (P = 0.029), and CD27 (P = 0.033). Eight pathways were confirmed by GSEA. CONCLUSION The established immunoscore can potentially serve as a candidate marker to estimate the OS for HBV-related HCC cases.
    • Qiang Wang; Qi Chen; Xia Zhang; Xiao-Lan Lu; Qin Du; Tao Zhu; Guo-Yuan Zhang; Dong-Sheng Wang; Qu-Ming Fan
    • 摘要: BACKGROUND Researchers have investigated the diagnostic value of protein induced by vitamin K absence or antagonist II (PIVKA-II) and alpha-fetoprotein (AFP) in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), and obtained abundant clinical diagnostic data. However, PIVKA-II and AFP have unsatisfactory specificity and sensitivity in the diagnosis of early-stage HBV-related HCC. Gamma-glutamyltransferase (γ-GT) and aspartate aminotransferase (AST) are common biomarkers for evaluating liver function, and we hypothesized that the γ-GT/AST ratio in combination with PIVKA-II and AFP would improve the diagnosis of early-stage HBV-related HCC. AIM To evaluate the diagnostic value of γ-GT/AST ratio alone or in combination with PIVKA-II and AFP in HBV-related HCC. METHODS Serum levels of γ-GT, AST, PIVKA-II, and AFP were detected and analysed in 176 patients with HBV-related HCC and in 359 patients with chronic hepatitis B. According to tumour size and serum level of HBV DNA, HBV-related HCC patients were divided into the following categories: Early-stage HCC patients, HCC patients, HBV DNA positive (HBV DNA+) HCC patients, and HBV DNA negative (HBV DNA-) HCC patients. Receiver-operating characteristic (ROC) curves were used to analyse and compare the diagnostic value of the single and combined detection of various biomarkers in different types of HBV-related HCC. RESULTS Tumour size was positively correlated with serum levels of PIVKA-II and AFP in HCC patients (r = 0.529, aP 0.05). When PIVKA-II was combined with the γ-GT/AST ratio in the diagnosis of earlystage HCC, HCC, and HBV DNA+ HCC, the AUROCs of PIVKA-II increased, with values of 0.857 vs 0.835, 0.925 vs 0.913, and 0.958 vs 0.954, respectively. When AFP was combined with the γ-GT/AST ratio in the diagnosis of early-stage HCC, HCC, HBV DNA+ HCC, and HBV DNA- HCC, the AUROCs of AFP increased, with values of 0.757 vs 0.621, 0.837 vs 0.744, 0.868 vs 0.757, and 0.840 vs 0.828, respectively. CONCLUSION The γ-GT/AST ratio may be better than PIVKA-II and AFP in the diagnosis of early-stage HBV-related HCC, and its combination with PIVKA-II and AFP can improve the diagnostic value for HBV-related HCC.
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