摘要：
Objective To study the diagnostic significance of whole blood sample index in the severity of hand, foot and mouth disease, and to analyze its pathogenesis. Methods 194 cases of severe cases of hand, foot and mouth disease were selected as the case group,and 193 cases of mild hand, foot and mouth disease were selected as the control group. Blood samples were collected after admission to study the whole blood samples, including white blood cells, erythrocytes, platelets, medium cell ratio, lymphocyte ratio, mononuclear cell ratio, C-reactive protein test; The patient's immune system, the nervous system were also tested. Results Compared with patients with mild group, the white blood cell level of the patients in the severe group was higher and the albumin level was higher, the difference was statistically significant (P<0.05), the monocyte ratio, the T cell ratio was lower, the difference was statistically significant (P<0.05). Conclusion The white blood cell level and monocyte ratio of patients with severe hand, foot and mouth disease have changed. The whole blood sample has a certain sensitivity to the diagnosis of severe hand, foot and mouth disease.%目的 研究全血样本指标在手足口病重症病例中的诊断意义,分析其发病机制.方法 选取在本院治疗手足口病重症病例患者194例作为病例组,另选同时期193例手足口病轻症患者为对照组,在入院后采集其血样进行全血样本分析,主要包括白细胞、红细胞、血小板、中细胞比率、淋巴细胞比率、单核细胞比率,C反应蛋白的检验;对患者的免疫系统、神经系统也进行一定的检验.结果 与轻症组的患者相比,重症组的患者的白细胞水平较高,白蛋白水平较高,差异具有统计学意义(P<0.05),单核细胞比率,T细胞比率较低,差异具有统计学意义(P<0.05).结论 手足口病重症患者的白细胞水平、单核细胞比率均有所改变,全血样本指标对重症手足口病患者的诊断有一定的敏感性.
