摘要:
目的::比较多排冠状动脉CT( MDCTA)和选择性冠状动脉造影( coronary angiography, CAG)在诊断常规心电图中完全性右束支阻滞( CRBBB)伴V1-V4导联ST-T改变患者,是否合并冠状动脉硬化性心脏病中的作用。方法:患者97例,年龄50~70岁,男72例,女25例,常规心电图显示完全性右束支阻滞伴V1-V4导联ST-T改变。64排螺旋CT,CTA检查穿刺桡静脉或肘静脉,心电门控步进式采集模式,钙化积分的量化采用国内外通用的Agatston积分,测试扫描延迟时间采用团注追踪法。三维后处理方法用病变部位冠状动脉长轴MPR及MIP、病变血管的CPR和VR,以及与横断面影像结合起来进行评估。 CAG检查采用Judkins方法,桡动脉或股动脉穿刺,全数字平板式心血管造影机( DSA),对左、右冠脉采用多体位投照,完成选择性冠脉造影。血管的狭窄程度判断如下:管径超过1.5mm的血管,≥50%为有意义病变。结果:与CAG比较,CTA结果阳性者,敏感度90.4%,特异度81.8%,假阳性率18.2%,假阴性率10.5%,似然比3.8,阳性预测值=79.2%,阴性预测值=91.8%;结论多排冠脉CT在诊断常规心电图中完全性右束支阻滞( CRBBB)伴V1-V4导联ST-T改变患者,是否合并冠状动脉硬化性心脏病中有很高的敏感度、特异度、似然比和阳性、阴性预测值、符合率85.6%、阳性符合率73.1%、阴性符合率76.3%。结论:为多排冠脉CT早期识别和评估冠状动脉硬化合并完全性右束支阻滞,对于心血管事件风险的减少具有重要意义。%Objective:To evaluate the usage of multi-detector computed tomography coronary angiography( MDCTA) in patients with complete right bundle branch block( CRBBB) accompany with ST-T changes of V1-V4 channels in electrocardiography( ECG) in dif-ferential diagnosis of coronary artery disease. Methods:97 cases,50-70 years old, 72males, 25females, with CRBBB accompany with ST-T changes of V1-V4 channels in ECG. 64-detector spiral CT, radial or elbow veins puncture , ECG gate-control , Agatston interg-ration, dumpling injective tracing to test scanning delay time. Three-dimension processing use long axis MPR &MIP of coronary artery lesions, CPR &VR , and graphy of cross-section. Coronary angiography( CAG) use Judkins method, radial or femoral artery puncture, all digital flat angiolgrahy machine(digital substract angiolgraphy, DSA). The diameters of coronary arteries ≥1. 5mm, if cramped≥50% are labeled positive. Results:Compared with CAG, CTA positive cases,sensitivity 90. 4%,specificity 81. 8%,rate of false positivity 18. 2%, rate of false negativity 10. 5%,likelihood ratio 3. 8,positive predictive value 79. 2%,negative predictive value 91. 8%, coinci-dence rate 85. 6%, positive coincidence rate 73. 1%, negative coincidence rate 76. 3%. Conclusion:MDCTA could play an important role in diagnosis of coronary artery disease accompany with CRBBB.