tobacco

摘要： Aluminum is an abundant metal in the earth’s crust that turns out to be toxic in acidic environments.Many plants are affected by the presence of aluminum at the whole plant level,at the organ level,and at the cellular level.Tobacco as a cash crop(Nicotiana tabacum L.)is a widely cultivated plant worldwide and is also a good model organism for research.Although there are many articles on Al-phytotoxicity in the literature,reviews on a single species that are economically and scientifically important are limited.In this article,we not only provide the biology associated with tobacco Al-toxicity,but also some essential information regarding the effects of this metal on other plant species(even animals).This review provides information on aluminum localization and uptake process by different staining techniques,as well as the effects of its toxicity at different compartment levels and the physiological consequences derived from them.In addition,molecular studies in recent years have reported specific responses to Al toxicity,such as overexpression of various protective proteins.Besides,this review discusses data on various organelle-based responses,cell death,and other mechanisms,data on tobacco plants and other kingdoms relevant to these studies.

摘要： The original article by Yuichi et al explored whether the Japan Narrow-Band Imaging Expert Team classification and the pit pattern classification are suitable for diagnosing neoplastic lesions in patients with ulcerative colitis.In this letter,we offer some other perspectives.Risk factors for colorectal tumors include type 2 diabetes.Among genetic factors,the deletion or mutation of some genes,such as the p53 gene,can lead to colorectal tumors.There are significant gender differences in the occurrence and development of colorectal tumors.Some nongenetic factors,such as smoking,are also associated with the development of colorectal tumors.These all suggest that colorectal tumors are not only caused by ulcerative colitis,and we suggest further exploration and differentiation between colitis and colorectal tumors.

摘要： Tobacco is an illicit product sold in the world and involves fatal communicable diseases and deaths. In several countries, tobacco revenue contributes to the health of victims. This study aimed to evaluate the contribution of tobacco taxes to the financing of the health system in Democratic Republic of the Congo (DRC) during the period of 3 years (from 2019 to 2021) in order to give some suggestions. A descriptive literature review on the tobacco tax was conducted from three tobacco tax collection services: the services of the General Secretariat of Health in DRC (SGSH), the Program of the National Health Account (PNHA) and the General Direction of Customs and Assizes (GDCA). The analysis revealed that no retrocession and no activity covered by the tax collected on tobacco does not contribute to the financing of the health sector, in order to reduce the burden of households already impoverished by diseases caused by tobacco.

摘要： [Objectives]This study was conducted to establish a reliable and unique molecular ID for flue-cured tobacco germplasm resources in Hunan Province,further improving the efficiency of germplasm collection and identification,and laying a solid material foundation for flue-cured tobacco breeding.[Methods]Twelve pairs of SSR primers with stable amplification and rich polymorphism were screened out from 816 pairs of SSR primers by a step-by-step screening method.As core primers of the SSR core primer library,the polymorphism of SSR primers was analyzed,the genetic relationship of 162 flue-cured tobacco germplasm resources was identified,and the molecular ID cards were constructed.[Results]The result of SSR primer polymorphism analysis showed that a total of 57 alleles were detected by 12 pairs of SSR primers in 165 tobacco germplasm resources,with an average of 4.75 alleles per pair of primers;the average diversity of SSR primers was 0.649;and the average value of Shannon's index was 1.235.The results of cluster analysis showed that 162 flue-cured tobacco germplasm resources were divided into five groups.The members of each group were divided based on genome information,which had nothing to do with their geographical origin.Meanwhile,12 pairs of SSR primers gave each flue-cured tobacco germplasm resource a unique molecular ID code.[Conclusions]From the above results,we can see that the 12 pairs of SSR primers obtained by screening have stable amplification polymorphism,and can serve as the primers of the core primer library,and can be used to construct the unique molecular ID of flue-cured tobacco germplasm resources.

摘要： [Objectives]To compare the benefits of different tobacco loading methods and supporting baking processes in intensive curing houses.[Methods]Flue-cured tobacco variety K326 was taken as material,and comparative experiment on baking effects of six tobacco loading methods(traditional hanging pole,loose leaf stacking,loose leaf binding and inserting,loose leaf inserting,loose leaf net basket,loose leaf grid)was conducted.[Results]Cost of dry tobacco loading equipment for hanging pole and loose leaf stacking was 0.01 and 0.1 yuan/kg,and cost of tobacco loading by loose leaf basket reached 0.36 yuan/kg.Labor cost for baking dry tobacco by direct stacking of loose leaves reached 2.02 yuan/kg,which was the lowest,while labor cost for binding and inserting loose leaves reached 2.44 yuan/kg,which was the highest.Energy consumption cost of dry tobacco baking with loose leaf grid was 1.06 yuan/kg,which was the lowest,while baking energy consumption cost of loose leaf stacking reached 1.23 yuan/kg,which was the highest.From the perspective of baking income,loose leaf inserting reached 21.36 yuan/kg,which was the lowest,while net basket reached 27.79 yuan/kg,which was the highest,followed by grid(23.46 yuan/kg)and loose leaf binding and inserting(22.5 yuan/kg).[Conclusions]It is worth popularizing the loose leaf binding and inserting and the loose leaf grid baking.

摘要： The WHO newsroom May 2020–states that tobacco epidemic is a gigantic public threat the world has ever faced.Furthermore,greater than 7 million deaths are owed to definitive tobacco usage&1.2 million due to non-smokers being exposed to secondhand smoke or passive smoking[2].Of preventable deaths,caused by use of tobacco,United States of America tops the list.Ironically,there is a steady decrease in estimated number of smokers globally and a rapid increase in number of vapers[3].Nicotine derived from tobacco or nicotiana tabacum is a component of E-cigarettes.Consumption of nicotine in any form has protracted ramifications on one’s health.

摘要： This study determined the concentrations and inhalation bioaccessibility of cadmium, chromium, nickel and zinc in some foreign and locally available tobacco snuff and leaves. For the determination of the heavy metals concentration, the samples were ashed and washed with hydrochloric acid according to standard method. The bioaccessibility test employed the Stimulated Epithelial Lung Fluid (SELF). The total concentration of heavy metals in the four samples investigated ranged between 9.7 - 14.9 μg/g, 24.1 - 37.0 μg/g, 41 - 69 μg/g and 153 - 183 μg/g for cadmium, chromium, nickel and zinc respectively. The percentage inhalation bioaccessibility fraction of the four samples investigated ranged between 20.8% - 59.8%, 3.3% - 8.1%, 21.7% - 48.8% and 7.6% - 12.5% for cadmium, chromium, nickel, and zinc respectively. Statistical analyses using SPSS 21, revealed significant differences in the total concentration of heavy metals in the samples investigated except for Zinc. Risk assessment based on daily consumption of 10 g of the tobacco snuff employing total concentration of the heavy metals suggests that excluding nickel, all other metals investigated indicated daily intake values above WHO permissible levels. However, with the bioaccessible fractions, only cadmium, a known carcinogen indicated levels above WHO limits. From the results of this study, it can be deduced that consumption of tobacco snuff may induce negative health effects such as cancer and its attendant complications, the risk analysis based on bioaccessible concentration suggests lower health risk than analysis based on total heavy metal concentration;hence the assumption that snuff is a safe alternative to tobacco smoking may be erroneous.

摘要： Malawi to begin cannabis cultivation for industrial hemp production in wake of tobacco slump Matilda Banda from the central region district of Kasungu in Malawi was a happy woman, but has seen her fortunes wane. The district is well known for growing tobacco,responsible for 60 percent of the country’s tobacco production, a crop that contributes11 percent to the GDP.

摘要： BACKGROUNDSmoking has detrimental effects on Crohn’s disease (CD) activity while data onulcerative colitis (UC) are conflicting. Little is known about the use and impact ofalternative smoking products in inflammatory bowel diseases (IBD).AIMTo understand the patients’ perceptions of the impact of smoking on their IBDand to assess differences between CD and UC patients.METHODSThe questionnaire was developed by Philip Morris Products SA in cooperationwith European Federation of Crohn's and Ulcerative Colitis Associations. Thefinal survey questionnaire consisted of 41 questions divided in 8 categories: (1)Subject screener;(2) Smoking history;(3) Background information;(4) IBD diseasebackground;(5) Current disease status;(6) Current therapeutics and medications;and (7) Current nicotine/cigarettes use and awareness of the impacts of smokingon IBD. The questionnaire was submitted online from 4th November 2019 to 11th March 2020 through the European Federation of Crohn's and Ulcerative ColitisAssociations website to IBD patients who were current smokers or had a historyof smoking.RESULTSIn total 1050 IBD patients speaking nine languages participated to the survey.Among them, 807 (76.9%) patients declared to have ever smoked or consumed analternative smoking product, with a higher proportion of current cigarettesmokers among CD patients (CD: 63.1% vs UC: 54.1%, P = 0.012). About twothirdsof the participants declared to have ever stopped cigarette smoking andrestarted (67.0%), with a significantly higher proportion among UC patientscompared to CD patients (73.1% vs 62.0%, P = 0.001). We also found significantdifferences between CD and UC patients in the awareness of the healthconsequences of smoking in their disease and in the perceived impact of smokingon disease activity, for both cigarettes and alternative smoking products.CONCLUSIONThis survey found significant differences between CD and UC patients in bothawareness and perception of the impact of smoking on their disease. Furtherefforts should be done to encourage smoking cessation for all IBD patients,including UC patients.

摘要： Glyphosate is a non-selective broad-spectrum herbicide that blocks plant growth by inhibiting 5-Enolpyruvylshikimate-3-phosphate synthase(EPSPS),a key enzyme of the shikimate pathway in microorganisms and plants.The full-length epsps cDNA sequence(paepsps,Genebank:KY860582.1)was cloned and characterized for the first time from Phragmites australis.The full-length cDNA of paepsps was 1308 bp encoding a polypeptide of 435 amino acids.The bioinformatic analyses showed that PaEPSPS has highly homologous with EPSPS from other plants.RT-PCR analysis of paepsps expression indicated that the gene expressed in leaves,stems,and roots,with higher expression in leaves.The expression of the paepsps gene increased with glyphosate application.In addition,the transgenic tobacco containing the paepsps gene showed glyphosate resistance in comparison with control.The novel paepsps is a good candidate gene in transgenic crops with glyphosate tolerance in the future.