摘要：
目的 探讨未破裂型输卵管妊娠患者妊娠黄体血流不同分级对保守治疗效果的影响.方法 对2013年2月至2018年2月沈阳军区总医院收治的未破裂型输卵管妊娠156例患者临床资料进行回顾性分析,以妊娠黄体血流不同分级进行分组,其中0级组36例、1级组41例、2级组45例、3级组34例.对4组患者保守治疗后血β?人绒毛膜促性腺激素(β?HCG)水平、包块变化情况、临床疗效进行统计比较.结果 0～3级组治疗后β?HCG下降至正常的时间分别为(14??4±2??7)、(16??2 ±3??9)、(23??3±4??8)、(27??0±4??6) d,组间比较差异有统计学意义(F＝5??338,P＝0??039);0～3级组治疗后包块完全消失的时间分别为(13??2±2??2)、(15??9±3??0)、(21??8±2??9)、(24??1±3??4) d,组间比较差异有统计学意义( F＝4??229,P＝0??043). 0～3级组患者治疗有效率分别为91??7%(33／36)、87??8%(36／41)、82??2%(37／45)、73??5%(25／34),组间比较差异亦有统计学意义( χ2＝4??586,P＝0??041).各组间不良反应发生率比较差异无统计学意义( P＞0??05).结论 未破裂型输卵管妊娠患者的妊娠黄体血流不同分级对保守治疗效果有明显影响,分级越高则所需的治疗时间越长且疗效也越差.%Objective To study the effect of different grades of corpus luteum blood flow on conservative treatment of unruptured tubal pregnancy??Methods One hundred and fifty?six patients who were diagnosed with unruptured tubal pregnancy in the General Hospital of Northern War Zone and accepted conservative treatment from February 2013 to February 2018 were retrospectively analyzed??The patients were divided into corpus luteum blood level 0 group(0 grade group,36 cases),corpus luteum blood level 1 group (1 grade group,41 cases),corpus luteum blood level 2 group(2 grade group,45 cases),corpus luteum blood level 3 group ( 3 grade group, 34 cases ) according to the corpus luteum blood flow classification in pregnancy??The levels of blood β?HCG,the packet reducing and the curative effect were compared among the four groups??Results The time ofβ?HCG decreased to normal after treatment in 0～3 grade group was (14??4 ±2??7) d, (16??2± 3??9) d, ( 23??3± 4??8) d, (27??0± 4??6) d respectively,there was significant difference among the four groups (F＝5??338,P＝0??039)??The time of mass disappeared completely after treatment in 0－3 grade group was (13??2±2??2) d,( 15??9± 3??0) d,( 21??8± 2??9) d,(24??1± 3??4) d respectively,there was significant difference among the four groups ( F＝4??229,P＝0??043)??The curative rate in 0－3 grade group was 91??7%(33／36),87??8%(36／41),82??2%( 37／45),73??5%( 25／34) respectively,there was significant difference among the four groups(χ2＝4??586,P＝0??041)??There was no significant difference in incidence of adverse reactions among the four groups ( P＞0??05)??Conclusion The different classification of corpus luteum blood flow in pregnancy of unruptured tubal pregnancy have significant influence on the conservative treatment effect??The higher the blood flow classification,the longer treatment time and the worse the curative effect??
