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摘要： Genetic polymorphism is associated with irritable bowel syndrome(IBS)in terms of susceptibility and clinical manifestations.Previous studies have shown that genetic polymorphism might play a key role in the onset and progression of IBS by modulating components of its pathogenesis such as the gut-brain axis,gastrointestinal motility,inflammatory activity,and immune status.Although underlying pathophysiological mechanisms have not been fully clarified,the potential ethnic differences that are present in worldwide genetic studies of IBS deserve attention.This review surveyed numerous studies focusing on IBSassociated single nucleotide polymorphisms,and investigated the ethnic disparities revealed by them.The results demonstrate the need for more attention on ethnic factors in IBS-related genetic studies.Taking ethnic backgrounds into accounts and placing emphasis on disparities potentially ascribed to ethnicity could help lay a solid and generalized foundation for transcultural,multi-ethnic,or secondary analyses in IBS,for example,a meta-analysis.Broader genetic studies considering ethnic factors are greatly needed to obtain a better understanding of the pathophysiological mechanisms of IBS and to improve the prevention,intervention,and treatment of this disease.

摘要： Although,liver transplantation serves as the only curative treatment for patients with end-stage liver diseases,it is burdened with complications,which affect survival rates.In addition to clinical risk factors,contribution of recipient and donor genetic prognostic markers has been extensively studied in order to reduce the burden and improve the outcomes.Determination of single nucleotide polymorphisms(SNPs)is one of the most important tools in development of personalized transplant approach.To provide a better insight in recent developments,we review the studies published in the last three years that investigated an association of recipient or donor SNPs with most common issues in liver transplantation:Acute cellular rejection,development of new-onset diabetes mellitus and non-alcoholic fatty liver disease,hepatocellular carcinoma recurrence,and tacrolimus concentration variability.Reviewed studies confirmed previously established SNP prognostic factors,such as PNPLA3 rs738409 for nonalcoholic fatty liver disease development,or the role of CYP3A5 rs776746 in tacrolimus concentration variability.They also identified several novel SNPs,with a reasonably strong association,which have the potential to become useful predictors of post-transplant complications.However,as the studies were typically conducted in one center on relatively low-to-moderate number of patients,verification of the results in other centers is warranted to resolve these limitations.Furthermore,of 29 reviewed studies,28 used gene candidate approach and only one implemented a genome wide association approach.Genome wide association multicentric studies are needed to facilitate the development of personalized transplant medicine.

摘要： Methylenetetrahydrofolate reductase(MTHFR)deficiency is the most common genetic cause of hyperhomocysteinemia,which has been implicated in the etiology of recurrent spontaneous abortion(RSA).This study was designed to investigate the association between two single nucleotide polymorphisms(SNP)(rs1801133[C677T]and rs1801131[A1298C])in the MTHFR gene and RSA,in Saudis.These two SNPs were selected as these polymorphisms have a different effect on the activity and stability of the enzyme,and significantly diverse effects have been reported in relation to the association with RSA.Ethical approval was acquired from the IRB at King Saud University(KKUH),Saudi Arabia,and written informed consent was obtained from each participant.The study group comprised of 100 Saudi women with unexplained RSA and 100 age-matched controls,both attending KKUH for a routine checkup.Blood was drawn in EDTA tubes,and DNA was extracted.Genotyping was conducted using TaqMan SNP genotyping assay kits.The frequency of the T allele of C677T was 0.165 in patients and 0.17 in controls.Genotype frequencies for CC,CT and TT genotypes were 70%,27%and 3%,respectively in RSA,and 71%,24%and 5%,respectively,in the controls(p>0.05).For the A1298C polymorphism,the C allele frequencies were 0.345 in patients and 0.28 in controls,while genotype frequencies for AA,AC and CC genotypes were 44%,43%,and 13%,respectively,in patients,and 54%,36%,and 10%,respectively,in controls(p>0.05).The frequency of CC genotype and C allele of A1298C were higher in the patients with RSA,but not significantly,while C677T genotypes and allele frequencies did not differ between patients and controls.The results suggested that MTHFR gene polymorphisms are population-specific and may not associate with RSA in Saudi women.

摘要： Objective.To investigate the clinical effect of single-row fixation and non-conjunction compression in the treatment of post small and medium rotator cuff injuries under arthroscopy.Methods.Forty-five patients admitted to our department from June 2018 to May 2019 were enrolled in the study.32 patients in the single-row fixed-group and 13 patients in the non-conjunctival group were randomly assigned.The VAS,ASES,and UCLA scores of the two groups were compared before surgery,one month,three months,and six months after surgery[1].Results.The VAS,ASES,and UCLA scores were significantly higher in those two groups other than the preoperative group.The scores of the two groups were gradually improved from one month,three months,and six months respectively after surgery.At one month,the scores of those two groups were statistically significant(P0.05).Conclusion.Under arthroscopy,the single-row fixation technique and the non-conjunction compression method were used to treat post small and medium rotator cuff injuries.The effect is very significant.In particular,the no-knot sputum method has a significant improvement in restoring postoperative pain,joint activity and joint strength.

摘要： Discharge of metals and their mineral flotation collectors into the soil environment causes severe ecological and health impacts, which is still not fully understood. This is of great concern, particularly with regards to their effect on the soil microorganisms whose functions determine not only the soil quality and function but also influence the air and water quality. This study aimed to analyze and compare, microcalorimetrically, the single chemical toxic effect with the combined effect of copper (Cu) and two of its main flotation collectors, potassium amyl xanthate (PAX) and sodium isoamyl xanthate (SIAX), on soil microbial community. All chemicals, individually and as a binary mixture of copper and each of its flotation collectors, exhibited a significant dose-effect relationship, and the highest and lowest microbial activity inhibition being associated with SIAX and Cu, respectively (e.g. IC 50 of 447.5, 158.3 and 83.9 μg·g?1 soil for copper, PAX and SIAX, respectively). For all cases, the microbial activity was more affected by the mixture than by the individual mixture components. Increasing the xanthates dose (from 25 to 100 μg·g?1 soil) in the mixture with a copper dose of 200 μg·g?1 soil led to the increase of the microbial activity inhibition rate, from 23.08 % to 53.85% in case of PAX and from 26.92% to 57.69% in case of SIAX). Similarly, the toxicity level of the mixture of equitoxic components doses increased with the increased mixture doses. Since the observed activity level can be attributed to the surviving microbes, capable of adapting to both chemical and their mixture, a genetically based analysis should be conducted to allow identifying and characterizing the potentially resistant strains that can be useful for the remediation of the pollution by copper and xanthates and for the sustainability of copper mining and flotation, and for all soil, water, and air quality and function interest.

摘要： Single photon sources are key components for quantum technologies such as quantum communication, computing and metrology. A key challenge towards the realization of global quantum networks are transmission losses in optical fibers. Therefore, single photon sources are required to emit at the low-loss telecom wavelength bands. However, an ideal telecom wavelength single photon source has yet to be discovered. Here, we review the recent progress in realizing such sources. We start with single photon emission based on atomic ensembles and spontaneous parametric down conversion, and then focus on solid-state emitters including semiconductor quantum dots, defects in silicon carbide and carbon nanotubes. In conclusion, some state-of-the-art applications are highlighted.

摘要： The concept of linear tangle was introduced as an obstruction to mixed searching number. The concept of (maximal) single ideal has been introduced as an obstruction to linear-width. Moreover, it was already known that mixed search number is equivalent to linear-width. Hence, by combining those results, we obtain a proof of the equivalence between linear tangle and maximal single ideal. This short report gives an alternative proof of the equivalence.

摘要： Single-photon sources are building blocks for photonic quantum information processes. Of the many single-photon generation schemes, electrically driven single-photon sources have the advantages of realizing monolithic integration of quantum light sources and detectors without optical filtering, thus greatly simplify the integrated quantum photonic circuits. Here, we review recent advances on electrically driven single-photon sources based on solid-state quantum emitters, such as semiconductor epitaxial quantum dots, colloidal quantum dots, carbon nanotubes, molecules, and defect states in diamond, SiC and layered semiconductors. In particular, the merits and drawbacks of each system are discussed. Finally, the article is concluded by discussing the challenges that remain for electrically driven single-photon sources.

摘要： The solid state single photon source is fundamental key device for application of quantum communication, quantum computing, quantum information and quantum precious metrology. After years of searching, researchers have found the single photon emitters in zero-dimensional quantum dots (QDs), one-dimensional nanowires, three-dimensional wide bandgap materials, as well as two-dimensional (2D) materials developed recently. Here we will give a brief review on the single photon emitters in 2D van der Waals materials. We will firstly introduce the quantum emitters from various 2D materials and their characteristics. Then we will introduce the electrically driven quantum light in the transition metal dichalcogenides (TMDs)-based light emitting diode (LED). In addition, we will introduce how to tailor the quantum emitters by nanopillars and strain engineering, the entanglement between chiral phonons (CPs) and single photon in monolayer TMDs. Finally, we will give a perspective on the opportunities and challenges of 2D materials-based quantum light sources.

摘要： Single-photon emitters (SPEs) are one of the key components in quantum information applications. The ideal SPEs emit a single photon or a photon-pair on demand, with high purity and distinguishability. SPEs can also be integrated in photonic circuits for scalable quantum communication and quantum computer systems. Quantum dots made from Ⅲ-Ⅴ compounds such as InGaAs or GaN have been found to be particularly attractive SPE sources due to their well studied optical performance and state of the art industrial flexibility in fabrication and integration. Here, we review the optical and optoelectronic properties and growth methods of general SPEs. Subsequently, a brief summary of the latest advantages in Ⅲ-Ⅴ compound SPEs and the research progress achieved in the past few years will be discussed. We finally describe frontier challenges and conclude with the latest SPE fabrication science and technology that can open new possibilities for quantum information applications.

摘要： Along with the rapid development of Internet technology, ecommerce is increasingly being accepted by the people. Ecommerce transactions via the Internet to achieve a convenient, ubiquitous businessfeatures, but this business model by the trading range of restrictions, the lack of movement flexibility. How toprovide their own value, it needs to break the traditional business model, build a new service model to provideusers more comfortable and convenient service. According to the principles of system design and system architecture, put forward a set of electronic payment channel for mobile services, architecture design, implementation and applications in this paper. The full technical program integrated application SWP patch card,dual SIM card interface chip, dualcore dualinterface SIM card, chip card, to achieve a set of efficient, safe,support multiple devices at the same time pay more than a new wireless no physical card-based payment system.

摘要： Along with the rapid development of Internet technology, ecommerce is increasingly being accepted by the people. Ecommerce transactions via the Internet to achieve a convenient, ubiquitous businessfeatures, but this business model by the trading range of restrictions, the lack of movement flexibility. How toprovide their own value, it needs to break the traditional business model, build a new service model to provideusers more comfortable and convenient service. According to the principles of system design and system architecture, put forward a set of electronic payment channel for mobile services, architecture design, implementation and applications in this paper. The full technical program integrated application SWP patch card,dual SIM card interface chip, dualcore dualinterface SIM card, chip card, to achieve a set of efficient, safe,support multiple devices at the same time pay more than a new wireless no physical card-based payment system.

摘要： Along with the rapid development of Internet technology, ecommerce is increasingly being accepted by the people. Ecommerce transactions via the Internet to achieve a convenient, ubiquitous businessfeatures, but this business model by the trading range of restrictions, the lack of movement flexibility. How toprovide their own value, it needs to break the traditional business model, build a new service model to provideusers more comfortable and convenient service. According to the principles of system design and system architecture, put forward a set of electronic payment channel for mobile services, architecture design, implementation and applications in this paper. The full technical program integrated application SWP patch card,dual SIM card interface chip, dualcore dualinterface SIM card, chip card, to achieve a set of efficient, safe,support multiple devices at the same time pay more than a new wireless no physical card-based payment system.

摘要： Along with the rapid development of Internet technology, ecommerce is increasingly being accepted by the people. Ecommerce transactions via the Internet to achieve a convenient, ubiquitous businessfeatures, but this business model by the trading range of restrictions, the lack of movement flexibility. How toprovide their own value, it needs to break the traditional business model, build a new service model to provideusers more comfortable and convenient service. According to the principles of system design and system architecture, put forward a set of electronic payment channel for mobile services, architecture design, implementation and applications in this paper. The full technical program integrated application SWP patch card,dual SIM card interface chip, dualcore dualinterface SIM card, chip card, to achieve a set of efficient, safe,support multiple devices at the same time pay more than a new wireless no physical card-based payment system.

摘要： Along with the rapid development of Internet technology, ecommerce is increasingly being accepted by the people. Ecommerce transactions via the Internet to achieve a convenient, ubiquitous businessfeatures, but this business model by the trading range of restrictions, the lack of movement flexibility. How toprovide their own value, it needs to break the traditional business model, build a new service model to provideusers more comfortable and convenient service. According to the principles of system design and system architecture, put forward a set of electronic payment channel for mobile services, architecture design, implementation and applications in this paper. The full technical program integrated application SWP patch card,dual SIM card interface chip, dualcore dualinterface SIM card, chip card, to achieve a set of efficient, safe,support multiple devices at the same time pay more than a new wireless no physical card-based payment system.

摘要： Along with the rapid development of Internet technology, ecommerce is increasingly being accepted by the people. Ecommerce transactions via the Internet to achieve a convenient, ubiquitous businessfeatures, but this business model by the trading range of restrictions, the lack of movement flexibility. How toprovide their own value, it needs to break the traditional business model, build a new service model to provideusers more comfortable and convenient service. According to the principles of system design and system architecture, put forward a set of electronic payment channel for mobile services, architecture design, implementation and applications in this paper. The full technical program integrated application SWP patch card,dual SIM card interface chip, dualcore dualinterface SIM card, chip card, to achieve a set of efficient, safe,support multiple devices at the same time pay more than a new wireless no physical card-based payment system.

摘要： 本发明涉及基于Single‑pass的聚类方法、系统、装置、存储介质，所提供方法具体是：设置新一轮循环中初次聚类的相似度；进而，根据Single‑pass以及初次聚类的相似度，进行聚类；进而，若有未被聚类的：根据上一次聚类的相似度以及预设的降值规则，获取相似度；将上一次聚类所得的短文本主题导入新一次聚类中，根据相似度以及Single‑pass，对上一次未被聚类的进行聚类；进而，判断获取相似度的步骤的执行次数是否已达到预设的总次数；进而，若未达到，跳转到获取相似度的步骤；若已达到，判断是否满足进行新一轮循环的条件；若满足，取倒数第二次聚类的相似度为最佳相似度；若不满足，跳转到设置相似度的步骤。同时解决了阈值难以确定以及长尾的问题。

摘要： 本发明提供本发明提供一种基于BTM和Single‑pass的热点话题发现方法，该方法首先利用BTM主题模型进行主题建模，获得语料数据集的主题分布，然后使用VSM进行向量化，再使用改进的Single‑pass算法对上面得到的结果进行聚类，对聚类结果进行整理得到新的聚类结果，其次，对上述热点话题发现方法进行并行化计算，以提高其在大数据量情况下的主题挖掘的速度。本发明可以很好的解决微博数据稀疏及处理海量数据的能力的问题，改进后的Single‑pass算法可以很好的降低计算复杂度，保持算法的稳定性，对新的数据能有效的进行处理，对热点话题的持续影响力有较好的计算分析，且数据集通过MapReduce框架提高数据处理效率的基础上，仍然能够保持话题发现质量。

摘要： 本发明提供了一种适用于Single‑pass京瓷喷头的水性高速喷墨打印热转印墨水,其包括以下原料：纳米色浆、多元醇、润湿剂、渗透快干剂、乳化剂B、杀菌剂和去离子水，所述色浆包括以下原料：无盐级精制超细分散染料色粉、分散剂、乳化剂A、甘油、杀菌剂、消泡剂和去离子水；本发明的水性高速京瓷喷墨热转印墨水，适用于京瓷头KJ4B‑600DPI的Single‑pass高速喷墨打印印花，打印流畅，待机性能好，快干性能好，打印性能稳定，无拉丝；其色彩稳定性和还原性好方便印花对版对色，印花品质高、成品一致性好、综合成本低、染料墨水无浪费节省资源，另外具有水洗4‑5级、干湿擦4‑5级、耐晒3.5‑5级等理化性能出色；墨水本身环保、无毒害，印花过程无需制版、无废水、废气产生，高效环保。

摘要： 本发明公开了一种大墨滴Single‑Pass和小墨滴Single‑Pass数码印花联合印花装置及其印花方法，包括机架、传动辊、输送带、大墨滴Single‑Pass数码印花机构和小墨滴Single‑Pass数码印花机构，小墨滴Single‑Pass数码印花机构和大墨滴Single‑Pass数码印花机构相配合，大墨滴Single‑Pass数码印花机构进行大底色喷墨，小墨滴Single‑Pass数码印花机构进行精细花型的喷墨，使得坯布在以上装置印花后既能达到传统圆网印花机的印花速度和底色鲜艳性，又能达到纯数码印花机图案的精细和线条的细腻性，大大提高了印花质量、印花产量，减少了污水排放成本，提高了工作效率。

摘要： 本发明属于喷墨打印技术领域，解决了现有技术中出墨量太大，出现开裂的现象，或出现极度扩散，形成墨点不清晰的问题，提供了一种Single‑Pass打印装置、控制方法及打印设备。该Single‑Pass打印装置包括用于喷射第一种墨水和第二种墨水的第一打印模组和第二打印模组；第一打印模组与第二打印模组间隔预设距离且在打印介质传动方向上并行排列设置；控制器，控制器将目标打印图像对应的打印数据中的墨水的墨量进行拆分；然后，控制器控制第一打印模组和第二打印模组按照相同区域以及拆分好的墨量进行喷墨打印以生成目标打印图像。通过对墨量拆分以及同区域的再次喷墨打印，在总墨量不变的情况下，实现单次出墨量减少，解决出墨量过大，造成墨点不清晰等问题。

摘要： 本发明题为基于合成字段的单发(SINGLE SHOT)预测。根据一个方面，基于合成字段的单发轨迹预测可包括：接收包括多个动因的环境的图像；从图像提取特征集；接收环境的图像；对来自图像的轨迹集进行编码；级联来自图像的特征集和轨迹集以生成交互模块输入；接收交互模块输入；对多个动因之间以及多个动因与环境之间的交互集进行编码；级联交互集和本地化合成字段标测图以生成解码器输入；接收解码器输入；生成本地化合成字段标测图和关联合成字段标测图；以及基于本地化合成字段标测图和关联合成字段标测图生成针对多个动因的轨迹预测集。

摘要： 本实用新型属于喷墨打印技术领域，解决了现有技术中出墨量太大，出现开裂的现象，或出现极度扩散，形成墨点不清晰的问题，提供了一种Single‑Pass打印装置及打印设备。该打印装置包括第一打印模组，存储有满足目标打印图像所需的第一墨量的第一种墨水和第二墨量的第二种墨水；第二打印模组，存储有满足目标打印图像所需的第三墨量的第一种墨水和第四墨量的第二种墨水；驱动机构，驱动打印介质朝向打印机构方向运动；第一打印模组与第二打印模组在打印介质传动方向上并行排列设置，第一打印模组喷墨打印的区域与第二打印模组喷墨打印的区域相同。通过对墨量拆分以及同区域的再次喷墨打印，实现单次出墨量减少，解决出墨量过大，造成墨点不清晰等问题。

摘要： 本实用新型属于喷墨打印技术领域，提供了一种Single‑Pass喷墨打印设备，该打印设备包括介质输送装置、传感器、第一喷墨机构和控制器，介质输送装置用于输送打印介质，且介质输送装置吸附打印介质在介质输送装置的工作面上；传感器用于在打印介质输送过程中检测打印介质是否达到预设位置，并产生位置信号；控制器分别与传感器、第一喷墨机构电连接，传感器依据接收到的位置信号并控制第一喷墨机构工作。本实用新型中介质输送装置依次输送打印介质经过传感器、第一喷墨机构，介质输送装置吸附打印介质在介质输送装置的工作面上，因此降低了输送过程中打印介质的偏移量，从而降低经过打印后打印介质上图案的偏移量，最终提高打印质量。

摘要： 本发明公开了一种基于single‑pass的文本聚类方法及其装置,首先通过对文本数据集进行预处理，得到文本数据信息；然后计算所述数据信息分词的TF‑IDF值；接着将得到权重最高的20个词使用CBOW词向量模型生成向量，最后根据所述文本数据信息中的词向量，通过文本聚类算法得到文本聚类结果，通过计算用户选择簇中心特征和簇内文本特征的jaccard相似系数，实现二次聚类。本发明通过增加聚类中心，使得新文档与簇进行计算时，只需要与簇内中心向量进行计算，大大减少了计算量，增加了计算的速率，并且通过jaccard相似系数，实现利用簇中心特征和文本特征对聚类结果的二次调整，优化输入数据顺序敏感问题。

摘要： 本发明公开了一种基于single‑spa的微前端技术，其技术方案要点是：包括用户，所述用户控制Nginx，所述Nginx数据连接有底层路由，所述底层路由数据连接有模块加载器，所述模块加载器通讯连接有main前端基础模块和至少三组APP软件，至少三组所述APP软件中包括有APP1、APP2和APP3，所述APP1通讯连接有server1，所述APP2通讯连接有server2，所述APP3通讯连接有url；利用装置可以在不同框架下的前端代码和应用的复用；实现了中大型应用的依赖升级和新技术的引入的平滑引入；将微服务的理念应用于浏览器端，即将Web应用由单一的单体应用转变为多个小型前端应用聚合为一的应用。各个前端应用还可以独立运行、独立开发、独立部署。