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壳核出血

壳核出血的相关文献在1988年到2022年内共计122篇,主要集中在神经病学与精神病学、外科学、内科学 等领域,其中期刊论文122篇、专利文献106813篇;相关期刊91种,包括中国综合临床、中华老年心脑血管病杂志、中国实用神经疾病杂志等; 壳核出血的相关文献由335位作者贡献,包括何祥、于守波、吴启东等。

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壳核出血

-研究学者

  • 何祥
  • 于守波
  • 吴启东
  • 吴建东
  • 吴忠斌
  • 夏吉勇
  • 孙树杰
  • 张兴春
  • 张向华
  • 朱焕春
  • 期刊论文
  • 专利文献

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    • 邓磊; 张珑; 袁丰; 张仁国; 汪美平; 张先斌
    • 摘要: 目的探讨方体定向置管血肿穿刺引流术与保守治疗在小量高血压壳核出血中的临床效果。方法选取112例小量高血压壳核出血患者,根据非随机临床同期对照研究及患者自愿原则将其分为方体定向置管血肿穿刺引流术组(微创组)和内科保守治疗组(保守组)。比较2组患者血肿清除率、神经功能恢复情况、日常活动能力、预后及术后并发症发生情况。结果微创组血肿清除情况优于保守组(P<0.05)。术后1周微创组美国国立卫生院卒中量表(NIHSS)评分低于保守组(P<0.05),格拉斯哥昏迷评分(GCS)高于保守组(P<0.05)。微创组术后并发症发生率低于保守组(P<0.05)。术后6个月微创组日常生活活动能力量表(ADL)评分、格拉斯哥预后评分(GOS)均高于保守组(P<0.05)。结论对小量高血压壳核出血患者给予方体定向置管血肿穿刺引流术治疗效果较好,能有效提高血肿清除率,减轻神经功能损伤,减少术后并发症,有利于患者预后的改善及术后日常生活能力的提高。
    • 袁淼; 翟安林; 王帆; 苟志勇
    • 摘要: Objective To investigate the therapeutic effect and inflammatory expression in keyhole craniotomy hematoma clearance curing the hypertensive putaminal hemorrhage.Methods Selected 112 patients of hypertensive putaminal hemorrhage in department of neurosurgery of the Second Affiliated Hospital of the North Sichuan Medical College between January 2011 and January 2017,they were divided into two groups depending on the operation;control group was operated through stereotaxic hematoma puncture drainage,experiment group was operated through keyhole craniotomy hematoma clearance;The therapeutic effect,post-operation complications and the Glasgow Outcome Scale (GOS),the inflammatory factor before and after the operation were compared.Results The therapeutic effect between the two groups is significant (P <0.05):Intracranial edema duration (t =5.117,P =0.001),Paralysis limb recovery time (t =3.953,P =0.003),Consciousness recovery (t =4.294,P =0.002),ICU hospitalization time (t =5.872,P =0.000);CRP,TNFα,IL-6 expressions reduce after the operation(P <0.05),the difference between the two groups is significant(P <0.05);Compared before and after surgery,CRP were as follow:the control group (F =61.030,P =0.000),the experimental group (F =64.684,P =0.000),Postoperative comparison between two groups (F =4.478,P =0.049);Compared before and after surgery,TNFαtas follow:the control group (F =75.686,P =0.000),the experimental group (F =51.150,P =0.000),Postoperative comparison between two groups (F =5.550,P =0.030);Compared before and after surgery,IL-6 as follow:the control group (F =39.125,P =0.000),the experimental group (F =126.189,P =0.000),Postoperative comparison between two groups (F =7.314,P =0.015);The post-operation complications between the two groups is significant (P < 0.05);Rebleeding (x2 =3.893,P =0.049),Intracranial infection (x2 =3.893,P =0.049),Lung infection (x2 =5.508,P =0.015),Urinary infection (x2 =4.807,P =0.024);The difference of GOS between the two groups is significant (x2 =3.972,P =0.036).Conclusion Keyhole craniotomy hematoma is effective in treating the hypertensive putiminal hemorrhage which can increase the therapeutic effect,reduce the post-operation complication.%目的 观察锁孔入路开颅血肿清除术治疗老年高血压性壳核出血临床疗效及其对炎性因子表达的影响.方法 选择2011年1月-2017年1月四川省绵阳市404医院(川北医学院附属第二医院)神经外科手术治疗的> 60岁高血压性壳核出血患者112例作为研究对象,根据手术方式不同分为2组.对照组50例采用立体定向血肿穿刺引流术,观察组62例采用锁孔入路开颅血肿清除术,观察术后2组患者临床疗效、术后并发症及格拉斯哥预后评分(GOS);所有患者于术前,术后3d、14 d采集患者静脉血标本检测炎性因子表达.结果 与对照组比较,观察组术后颅内水肿持续时间明显缩短、瘫痪肢体恢复早、意识恢复快、ICU留置时间短(t=5.117、3.953、4.294、5.872,P=0.001、0.003、0.002、0.000).术后2组患者CRP、TNF-α、IL-6表达均较术前降低(对照组F=61.030、75.686、39.125,P均=0.000;观察组F=64.684、51.150、126.189,P均=0.000),但观察组术后降低更明显(P<0.05).观察组术后再出血及颅内、肺部、尿路感染例数均明显低于对照组(P<0.05).术后3个月随访,观察组患者GOSⅣ级明显优于对照组(x2=3.972,P=0.036).结论 对于老年高血压壳核出血患者,锁孔入路血肿清除术临床疗效及预后佳,术后并发症发生率低.
    • 顾应江; 侯小林; 杨东东; 李定君; 李成勋; 曾林
    • 摘要: Objectives To conduct grading comparison for the damage degree of pyramidal tracts after procedure in patients with unilateral hypertensive putamen hemorrhage via transsylvian-transinsular (TS-TI) approach and transcortical transtemporal (TC-TF) approach using magnetic resonance diffusion tensor imaging (DTI) and to evaluate the postoperative recovery of the patients according to the quality criteria of the activities of daily living (ADL),and to identify the advantages and disadvantages of both surgical approaches.Methods Sixty-three consecutive patients with first onset of unilateral hypertensive basal ganglia putamen hemorrhage admitted to Department of Neumlsurgery in Affiliated Hospital of Southwest Medical University of Traditional Chinese Medicine were enrolled prospectively.The volume of hematoma at admission was 26-45 ml.They were randomly divided into group A and group B by random number table.The patients in group A (n =31) were treated via the TS-TI approach,and those of group B (n =32) were treated via the TC-TT approach.The operator was the same surgeon.The patients of rebleeding were excluded (4 in group A,7 in group B),and 52 patients were actually included,including 27 in group A and 25 in group B.The DTI examinations were perforrned 5 to 8 d after procedure.The image data were processed by PHILIPS Extended MR Workspace 2.6.3.4 (EMW 2.6.3.4) software.The bilateral pyramidal tracts were reconstructed,the damage degree of pyramidal tract and its relationship with hematoma and surgical approach were observe respectively.The ADL quality criteria were used to evaluate the recovery at 3 months after procedure.The SPSS 17.0 software was used to conduct rank sum test for the pyramidal tract injury grade after procedure in both groups.The number of rebleeding in the operation areas and the ADL quality criteria evaluation were tested by Chi-squared test.Results There was no significant difference in the postoperative rebleeding rate between group A (12.9%,4/31) and group B (21.9%,7/32) (x2 =0.367,P =0.545).The postoperative pyramidal tract damage degree of group A was better than that of group B.There was significant difference (U =180.00,P =0.004).The comparison of ADL quality evaluation in both groups after procedure showed that the good prognosis rate (81.5%,22/27) of group A after procedure was better than that of group B (56.0%,14/25).There was significant difference (x2 =3.957,P =0.047).Conclusions The three-dimensional relationship between the hematoma lesions and the pyramidal tracts was observed by DTI,the damage degree of the pyramidal tracts were identified.The TS-TI approach was superior to the TC-TF approach in the postoperative damage degree of pyramidal tract and the quality of ADL for the treatment of hypertensive putamen hemorrhage.%目的 利用磁共振扩散张量成像(DTI)技术对经外侧裂岛叶(TS-TI)及颞叶皮质(TC-TT)手术入路的单侧高血压壳核脑出血患者术后锥体束损伤程度进行分级比较,结合日常生活活动(ADL)质量标准评价患者术后恢复情况,判断该两种手术入路优劣.方法 连续性前瞻性入选2016年1月至2017年6月西南医科大学附属中医医院神经外科收治的63例首次发病的单侧高血压基底节区壳核出血患者,入院时血肿体积26 ~ 45 ml.按随机数字表将患者完全随机分为A组与B组,A组(31例)患者采用TS-TI入路,B组(32例)患者采用TC-TT入路,术者为同一位医师.排除术后再出血者(A组4例,B组7例),实际纳入患者共52例,A组27例,B组25例.DTI检查为术后5 ~8d,影像数据经PHILIPS Extended MR Workspace 2.6.3.4(EMW 2.6.3.4)软件进行后处理,重组双侧锥体束,分别观察锥体束损伤程度及其与血肿、手术入路关系;利用ADL质量标准评价患者术后3个月恢复情况.采用SPSS 17.0软件对两组术后锥体束损伤分级行秩和检验,术区再出血例数、ADL质量标准评价行x2检验.结果 A组术后再出血率(12.9%,4/31)与B组(21.9%,7/32)比较,差异无统计学意义(x2=0.367,P=0.545).术后A组锥体束损伤程度轻于B组,差异有统计学意义(U=180.00,P=0.004);术后两组ADL质量评价比较,A组术后预后良好率(81.5%,22/27)优于B组(56.0%,14/25),差异有统计学意义(x2=3.957,P=0.047).结论 利用DTI观察血肿病灶与锥体束的三维立体关系,可判断锥体束受损程度;TS-TI入路治疗高血压壳核脑出血在术后锥体束损伤及ADL质量方面优于TC-TT入路.
    • 柴清喜; 姜占涛; 霍晓锋; 李建军; 解思云
    • 摘要: 目的 探讨经外侧裂入路壳核区脑出血微创清除术的临床效果.方法 选取2012年9月至2014年9月许昌市人民医院神经外科收治的高血压脑出血中壳核区脑出血患者47例,均采用经外侧裂入路微创清除壳核区脑出血.结果 47例患者中恢复良好25例,轻残13例,中重残6例,死亡3例,死亡率6.38%.结论 采用经外侧裂入路微创清除壳核区脑出血损伤小,预后好,可明显提高患者的术后生存质量.
    • 杨金理; 冯志铁; 谭秀茹; 曾昭明; 黄开让
    • 摘要: 目的:分析比较经外侧裂岛叶入路和经颞叶皮质入路治疗壳核出血的效果。方法:选取阳江市人民医院2011年3月至2016年12月共65例壳核出血患者,根据治疗方式的不同,分为观察组35例和对照组30例,观察组采用外侧裂岛叶入路治疗的方式,对照组采用经颞叶皮质入路治疗的方式,对比两组患者的临床疗效。结果:观察组患者血肿清除率、不良反应发生率、意识状态以及神经功能均优于对照组患者,差异具有统计学意义(P<0.05)。结论:经外侧裂岛叶入路和经颞叶皮质入路均有着较明显的效果,但前者治疗优势更明显。
    • 陈伟强; 彭国毅; 杨金华; 肖哲; 张子衡; 罗成
    • 摘要: 目的 探讨不同手术入路治疗高血压性左侧壳核出血的效果.方法 选择2003年1月~2009年12月于汕头大学医学院第一附属医院(以下简称“我院”)早期急诊行经侧裂-岛叶入路显微手术清除血肿的69例高血压性左侧壳核出血患者作为观察组,选择我院同期行经颞叶皮质入路手术治疗的58例患者作为对照组.观察两组患者血肿清除率、再出血发生率、术后失语情况及术后3个月的预后情况.结果 观察组大部分血肿清除率高于对照组[69.6%(48/69)比44.8%(26/58)],再出血发生率低于对照组[10.2%(7/69)比31.0%(18/58)],观察组患者未见完全失语者,无失语率明显高于对照组[71.0%(49/69)比3.5%(2/58)],两组比较差异均有统计学意义(P<0.05).术后3个月随访,观察组预后优良率明显高于对照组[63.8%(44/69)比32.8%(19/58)],两组比较差异有统计学意义(P< 0.05).结论 经外侧裂-岛叶人路治疗高血压性壳核出血的效果优于经颞叶皮质人路,其具有血肿清除效果好、止血方便、对脑组织损伤小、对语言功能的影响小等优势,值得临床推广应用.
    • 王辉; 冯金州; 张照立; 王富启
    • 摘要: 目的 观察方体定向血肿吸引术治疗72例高血压患者壳核出血的安全性.方法 选取河南省兰考县人民医院收治的高血压壳核出血患者72例,分为A组与B组,各36例;A组实施经外侧裂岛叶入路术治疗,B组实施方体定向血肿吸引术治疗,比较A、B组患者的治疗效果及安全性.结果 与A组相比,B组治疗有效率较高,并发症发生率低,差异有统计学意义(P<0.05).结论 对高血压壳核出血患者采用方体定向血肿吸引术治疗,效果显著,安全性和应用价值较高.
    • 孙俊启; 毕彩琴; 汪青松
    • 摘要: 目的探讨颅内血肿微创清除术治疗小量高血压性壳核出血的疗效,为临床治疗小量高血压性壳核出血提供参考。方法选择住院治疗的80例小量高血压性壳核出血患者,根据治疗方法不同分为对照组和观察组各40例。对照组采用常规内科保守治疗,观察组在内科保守治疗的基础上接受颅内血肿微创清除术。分别于治疗后第1天、第1周、第2周及第3周测量2组患者颅内剩余血肿量、血肿周围水肿量并进行神经功能缺损程度评分,并对测量值及评分结果进行比较。治疗后第3周2组患者进行显效率比较。治疗后3个月2组患者进行日常生活能力比较。结果观察组在治疗后第1天、第1周、第2周、第3周颅内剩余血肿量、血肿周围水肿量均明显少于同时期的对照组,2组差异有统计学意义(P<0.01);观察组在治疗后第1天、第1周、第2周、第3周神经功能缺损评分明显小于同时期的对照组,2组差异有统计学意义(P<0.01);观察组治疗后第3周临床疗效显效率高于对照组,2组差异有统计学意义(P<0.05);观察组治疗后3个月日常生活能力评分好于对照组,2组差异有统计学意义(P<0.05)。结论颅内血肿微创清除术治疗小量高血压性壳核出血,能够较快地清除颅内血肿,减轻颅内水肿,改善神经缺损程度,提高患者的生活质量,其疗效优于内科保守治疗,是比较安全、有效的一种治疗方法。
    • 白杨; 王东; 苏醒; 周志中
    • 摘要: 目的 探讨自制激光辅助立体定向头架行血肿腔穿刺置管治疗高血压脑出血的效果. 方法 对吉林市中心医院神经外科自2013年1月1日至2014年1月1日收治的67例壳核出血患者应用自制激光辅助立体定向头架行颅内血肿腔穿刺置管治疗(微创组),并以采用传统开颅手术方式治疗的53例同期壳核出血患者为对照(传统开颅组),对2组患者的手术效果进行系统分析和评价. 结果 微创组患者与传统开颅组患者比较,术后6个月内死亡率明显降低(8.9% vs22.6%)、再出血率明显降低(2.99% vs 15.1%)、6个月良好率明显升高(68.7% vs 43.4%)、平均手术时间明显缩短[(41.2±8.1) rain vs (203.2±38.6) min]、平均住院时间明显缩短[(18.2±4.4)d vs(28.1±7.2)d]、平均住院费用明显减少[(23647.7±5503.2)元vs(51678.6±7524.2)元],差异均有统计学意义(P<0.05). 结论 采用自制激光辅助立体定向头架进行颅内血肿腔穿刺置管治疗壳核出血操作简便、费用低廉、效果良好.%Objective To study the effect of self-made stereotactic head frame on hypertensive cerebral hemorrhage.Methods Sixty-seven patients with putamen hemorrhage,admitted to our hospital from January 1,2013 to January 1,2014,were enrolled as minimally invasive group;a self-made laser assisted stereotactic head frame was used to putaminal intracranial catheter.Another 53 patients with putaminal hemorrhage,performed traditional craniotomy at the same time period,were enrolled as control group.Systemic analysis and evaluation of effect of these two methods were performed.Results As compared with the control group,minimally invasive group had significantly lower mortality rate 6 months after surgery (22.6% vs.8.9%) and re-bleeding rate (15.1% vs.2.99%),significantly increased percentage of favorable outcomes (43.4% vs.68.7%),statistically shorter surgical times ([203.2±38.6] min vs.[41.2±8.1] min) and hospital stays ([28.1±7.2] d vs.[18.2±4.4] d),and significantly decreased medical expenses ([23647.7±5503.2] yuan vs.[51678.6±7524.2] yuan,P<0.05).Conclusion Treating putaminal hemorrhage using self-made laser assisted stereotactic head frame enjoys advantages as simple operation,lower cost and good efficacy.
    • 温洪汉
    • 摘要: 目的比较经外侧裂岛叶入路和经颞叶皮质入路两种手术入路治疗壳核出血的临床疗效及优劣性。方法选取2011‐12—2013‐12我院收治的100例高血压性壳核出血患者作为研究对象,按随机数表法分为A组和B组,每组各50例。A组患者采取经外侧裂岛叶入路清除血肿,B组患者采取经颞叶皮质入路手术清除血肿。观察2组患者的治疗后的止痛效果及各项生活质量得分变化情况。结果 A组患者术后血肿大部分清除33例(66%),明显多于B组的22例(44%),再出血5例(10%),少于B组的15例(30%),意识状态及神经功能好转29例(58%),多于B组;A组患者术后预后良好38例(76%),多于B组的26例(52%),而完全性失语1例(2%),明显少于B组的12例(24%),2组比较差异有统计学意义( P<0.05)。结论经外侧裂岛叶入路较经颞叶皮质入路在手术清除壳核血肿的治疗中具有更大的优势,值得临床推广。%Objective To investigate the curative effect comparison of lateral fissure insular approach and temporal cortex approach on treating patients with putamen hemorrhage.Methods 100 patients with hypertensive putamen hemorrhage in our hospital from December 2011 to December 2012 were randomly divided into A group (n=50 ,treated with lateral fissure insular approach) and B group (n=50 ,treated with temporal cortex approach).The curative effect and life quality of two groups were compared.Results The hematoma clearance ,consciousness state and nerve function improvement rate ,and good postoperative prognosis rate in A group were more than these in B group (66% vs 44% ,58% vs 36% ,76% vs 52% ,respectively).The bleeding rate again and complete aphasia rate in A group were lower than these in B group (10% vs 30% ,2% vs 24% ) ,which had significant difference.Conclusion The curative effect of lateral fissure insular approach has better than that of temporal cortex approach ,which is worthy of application.
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