profile

摘要： Objective:Cholesteryl esters(CEs)are composed of various fatty acyl chains attached to the hydroxyl groups of cholesterol,and abnormalities in their metabolism are related to many diseases.This study aimed to develop an ultrahigh-performance liquid chromatography-quadrupole exactive mass spectrometry(UPLC-Q-Exactive MS)method to identify the CEs in plasma.Methods:First,the MS fragmentation patterns were investigated using seven commercial CE standards.Then,the CEs in plasma were characterized through the accurate mass data of precursor ions and characteristic product ions.A strategy of step-by-step m/z scans in a narrow range was proposed to identify more trace CEs by the full-scan data-dependent MS/MS(ddMS2)mode.Results:A total of 50 CE species consisting of 55 regioisomers were identified in human plasma.Among them,two species were reported for the first time.Conclusion:This study is the most comprehensive identification of CE species in human plasma to date.These results will contribute to the in-depth profiling of CEs in human plasma and provide guidance for animal model selection when studying lipid-related diseases.

摘要： The high frequency of dental extractions creates a high demand for prosthetic rehabilitation. Therefore, this study aimed to describe the profile of consumers of prosthetic care at the Institute of Odontology and Stomatology in Dakar. It was a descriptive and retrospective study of patients who had been consulted at the prosthetic clinic of the Institute of Odontology and Stomatology of Dakar. Data were collected from medical records from 09 November 2019 to 09 June 2020. The tools used to collect and process the information were the Sphinx software and the Excel spreadsheet. Out of the 101 patient records, 51% were male and 48% belonged to the age group of 18 to 39 years. Nearly 38.61% of the patients lived less than 5 km from the health care facility and 70.3% of the respondents had a monthly income of fewer than 100,000 FCFA. Clinically, 96% of patients came for functional reasons, 78.2% for aesthetic reasons, and partial edentulism was the most frequent diagnosis (96%). Chi-square tests were performed to find a dependency or non-dependency relationship between diagnosis and age, but also between income and treatment cost. In sum, age and diagnosis were independent of each other, just as patient income was not related to treatment cost. Proximity to health facilities, income, and cost of treatment are factors that influence accessibility to oral health care. It is important to integrate the profile of the consumer of care into global management.

摘要： Silicon etching is an essential process in various applications,and a major challenge for etching process is anisotropic high aspect ratio etching characteristics.The etch profile is determined by the plasma parameters and process parameters.In this study,the plasma state with each process parameters were analyzed through the optical emission spectroscopy(OES)plasma diagnostic sensor by both chemical and physical approaches.Electron temperature and electron density were additionally acquired using the corona model with OES data that provides chemical species information,and the etch profile was evaluated through scanning electron microscope measurement data.The results include changes in profile with gas ratio,bias power,and pressure.We figure out that factors like ion energy and ion angular distribution as well as chemical reaction affect the anisotropic profile.

摘要： Dear editor,Congestion games(CGs)proposed in[1]are noncooperative games in which a collection of players compete over a finite set of resources.In CGs,the cost incurred by each player depends only on the resource that the player chooses and the number of players choosing the same resource.Because of their potential across a range of fields,CGs have been applied to practical problems such as network routing and road pricing.Furthermore,CGs can be modeled as evolutionary congestion games(ECGs)if they are played repeatedly.

摘要： In the robotic welding process with thick steel plates,laser vision sensors are widely used to profile the weld seam to implement automatic seam tracking.The weld seam profile extraction(WSPE)result is a crucial step for identifying the feature points of the extracted profile to guide the welding torch in real time.The visual information processing system may collapse when interference data points in the image survive during the phase of feature point identification,which results in low tracking accuracy and poor welding quality.This paper presents a visual attention featurebased method to extract the weld seam profile(WSP)from the strong arc background using clustering results.First,a binary image is obtained through the preprocessing stage.Second,all data points with a gray value 255 are clustered with the nearest neighborhood clustering algorithm.Third,a strategy is developed to discern one cluster belonging to the WSP from the appointed candidate clusters in each loop,and a scheme is proposed to extract the entire WSP using visual continuity.Compared with the previous methods the proposed method in this paper can extract more useful details of the WSP and has better stability in terms of removing the interference data.Considerable WSPE tests with butt joints and T-joints show the anti-interference ability of the proposed method,which contributes to smoothing the welding process and shows its practical value in robotic automated welding with thick steel plates.

摘要： Objective To evaluate the effect of the thickness and area of the cavity between bolus and skin upon the dose deposition in the shallow tissues.Methods The linear accelerator head model of 6 MV X ray was constructed using Geant4,which simulated the accelerator working condition of 10 cm× 10 cm field and recorded the information of emergent particles as phase space file.A water phantom of 30 × 30 × 30 cm3 was designed at the SAD level.A 30 cm × 30 cm × 1 cm water film was constructed adjacent to or with different cavities to the upper surface of the phantom.The phase space file was utilized as particle source to simulate the particle transport process.The axis depth dose distribution and lateral dose profiles in the center area of the field at a depth of 1 mm,5 mm,9 mm,15 mm and 21 mm of the phantom were obtained,respectively.The simulated data obtained from water film with different cavities were compared with those of adjacent to the water phantom.Results When the cavity was ≤ 5 mm,the cavity exerted slight effect.When the thickness was increased,the maximum dose depth (Dmax) was increased,the PDD at Dmax (PD Dmax) became less,the depth of influenced lateral dose profiles was increased and the dose in the center area was decreased.Along with the increase of cavity area,the Dmax was initially increased and then decreased,the PD Dmax was at first decreased and subsequently increased,the depth of influenced lateral dose profile was initially increased and then decreased,the dose in the center area was first decreased and subsequently increased.The lateral dose profile distant from the cavity or located at a depth ≥ 15 mm was almost not affected by the cavity.Conclusion The thickness of the cavity between bolus and skin should be less than 5 mm and the cavity area should be small as possible.%目的 研究Bolus与皮肤间空腔厚度和面积对浅层组织剂量的影响.方法 运用Geant4构建出射6MVX线的加速器模型,模拟10 cm× 10 cm射野下出束情况并记录出射粒子相空间文件.在源轴距水平构建30 cm×30 cm×30 cm水模体,分别在其靠近加速器一侧构建紧贴模体表面及含有不同空腔的30 cm×30 cm×1 cm水膜,以相空间文件作入射粒子源,模拟粒子输运过程,获取水模体中心轴深度剂量分布和射野中心区域不同深度处侧向剂量profile.将含有不同空腔时的模拟数据与水膜和水模体紧密贴合时的数据进行对比.结果 空腔厚度≤5 mm时,影响较小,之后随厚度增加,最大剂量深度(Dmax)增加,对应处百分深度剂量减小,侧向剂量profile受影响深度增加,中心区域剂量减小;随空腔面积增加,Dmax先增大后减小,对应处百分深度剂量先减小后增加,侧向剂量profile受影响深度先增加后减小,中心区域剂量先减小后增加;在远离空腔及深度≥15 mm时侧向剂量profile基本不受影响.结论 使用Bolus时其下空腔厚度应在5 mm以内,面积尽量小.

摘要： Di.Hefeng Huang received her Bachelor''s degree in 1982 and Master''s degree in 1989 from the Zhejiang Medical University,now known as the Zhejiang University Medical School in Hangzhou,China.After graduation,she served as a doctor of obstetrics and gynecology at the Zhejiang Women''s Hospital,School of Medicine,Zhejiang University.From 1990 to 1991,she underwent training for assisted reproduction technology(ART)at the Queen Mary Hospital of the Hong Kong University.Subsequently,she returned to the Zhejiang Women''s Hospital and established and led the Reproductive Center of Zhejiang Province from 1991 to 2013.

摘要： Cerebral or intracranial aneurysm is a leading cause of subarachnoid hemorrhage. It was initially treated with open surgical clipping but as rapid development of technology a less invasive endovascular coiling technique of aneurysm revolutionized the treatment. Due to tortuous anatomy of parent artery and complicated morphology and location of aneurysm there is ongoing challenge in the complete obliteration of aneurysms. To aid in the advances of treating aneurysm stent assisted endovascular coiling was introduced to give more scaffold support to parent artery and decrease events of coil protrusion from aneurysms. Many types and generation of stents were developed. One of the most recently introduced stent is low profile visualized intraluminal support (LVIS) stent. Due to its low profile nature it can be used in 0.017-inch inner diameter microcatheter and reach small and complex vessels providing high aneurysmal neck coverage which was not possible through other traditional stent. In addition, its braided design with tantalum strands and radiopaque markers make it more visible during stent placement and post procedure stent evaluation. Despite of many advantages of LVIS stent it is related to high rate of thromboembolic complications and technical complications. Aim of this review paper was to evaluate therapeutic safety, effectiveness and feasibility of LVIS stent in endovascular coil embolization of intracranial aneurysms.

摘要： 本发明公开了一种Profile下载方法、移动终端及可读存储介质，该方法包括：当接收到Profile下载信息时，向eSIM卡设备请求eSIM卡的身份认证信息，并验证身份认证信息；若所述身份认证信息通过验证，则当监测到Profile下载确认指令时，将Profile下载信息和身份认证信息发送至Profile下载服务器；接收Profile下载服务器返回的Profile数据，并将Profile数据发送至eSIM卡设备，以供eSIM卡设备将所述Profile数据写入eSIM卡中。本发明能够有效的提高Profile的下载便利性。

摘要： 本发明公开了一种UPLC‑HRMS Profile模式非靶向代谢轮廓数据自动解析的方法，针对样品UPLC‑HRMS非靶标代谢轮廓解析获得样品中化学成分信息。该方法首先将UPLC‑HRMS Profile模式数据根据不同仪器自适应转化为Centroid模式数据；在转化后色谱信号的基础上按照预先设定的m/z精度进行聚类，选取强度最大的离子作为种子，估计EIC范围计算离子密度，实现EIC的构建；对所有m/z对应的EIC利用局部极小值实现基线校正；待基线校正后，利用多尺度平滑卷积运算结合窗口拓展的策略获得各EIC中的色谱峰位置，根据色谱峰的位置，提取对应的色谱峰；根据保留时间和色谱峰形相似以及碎片离子m/z差值实现峰注释；并根据峰高相似性实现碎片离子的识别，最终实现样品数据的自动化解析。

摘要： 本发明提供一种Profile的迁移方法、装置、SM‑DP+及运营商后台系统，该方法包括：获取第一设备的第一迁移请求信息，根据所述第一迁移请求信息，生成所述目标Profile的迁移令牌；接收第二设备发送的第二迁移请求信息；根据所述第一设备的eSIM卡的标识信息对所述迁移令牌进行检查，若检查通过，将所述迁移令牌中携带的目标Profile的标识信息与所述第二设备的eSIM卡的标识信息绑定；向第二设备发送所述目标Profile；本发明实施例提供了将Profile从第一设备迁移到第二设备的方法，SM‑DP+无需生成新的Profile，只需复用旧的Profile；且运营商后台系统无需将手机号与新的Profile绑定，避免后台改造。

摘要： 一种基于UICC进行远程Profile管理的方法，运营商业务系统下发Profile到SMDP+中，其中Profile的PE中包含管理小程序，当Profile被用户终端下载和安装时，管理小程序也被用户终端下载和安装，并且在Profile被启用时，管理小程序也被自动激活运行；运营商业务系统接收由BIP服务器所转发过来的用户终端的状态信息，其中用户终端的状态信息由用户终端的管理小程序向BIP服务器上报而来；运营商业务系统根据状态信息判断是否向BIP服务器下发Profile回收指令，其中下发到BIP服务器的Profile回收指令能够被用户终端通过管理小程序查询到，以使得用户终端根据Profile回收指令进行相应动作。

摘要： 本发明公开了一种基于MatrixProfile的时间序列变长模体挖掘方法，步骤为：1.弱标记片段提取：对时间序列分段加入弱标记，提取弱标记时间序列片段。2.长度为w的模体发现：2.1最小窗口值即w＝2时片段内字典生成：以STAMP算法为子程序，找出候选子序列存入字典。2.2全局模体发现：将所有的弱标记时间序列片段连接形成新的时间序列，在新的时间序列上利用字典进行模体发现。2.3窗口值在指定窗口值内增加时，利用下界距离找出候选子序列存入字典，减少字典生成的工作量，重复全局模体发现步骤，完成模体发现。本发明不是在整个时间序列上进行模体发现，而是通过通过连接弱标记时间序列片段形成新的时间序列，从而缩短了模体搜索空间，进而提高了模体发现的效率。

摘要： 本申请涉及一种Profile应用管理方法及装置，涉及通信技术领域，该方法包括以下步骤：获取Profile共性应用；比对Profile下载指令对应的第一Profile与安全域内的Profile共性应用，获取并下载第一Profile中不包括安全域内的Profile共性应用的第一特性Profile文件；基于第一特性Profile文件调用对应的Profile共性应用执行对应的应用功能。本申请对Profile文件中的应用进行特性和共性的区分，预先存储共性应用，后期只需下载不包括共性应用的Profile文件，在Profile文件的管理工作中提高管理效率和降低资源占用率。

摘要： 本发明涉及一种终端切换Profile的方法、eSIM卡及终端，属于eSIM卡技术领域，该方法包括以下步骤：S1、终端复位后，初始化eSIM卡的RAM；S2、终端冷复位后，从eSIM卡的EEPROM中第一存储空间获取默认Profile标识；终端热复位后，从eSIM卡的RAM中第二存储空间获取第一Profile标识；S3、根据默认Profile标识或第一Profile标识启动对应的Profile，从而终端通过所述Profile接入对应网络；S4、根据Profile切换指令，将第二Profile标识写入RAM中的第二存储空间；S5、终端热复位，初始化RAM，不初始化第二存储空间；S6、从RAM的第二存储空间中获取第二Profile标识，根据第二Profile标识启动对应的第二Profile，从而终端通过第二Profile接入对应网络。本发明提供的切换Profile的方法、eSIM卡及终端能够保证在频繁切换号码的场景下不影响卡片寿命。

摘要： 本申请提供一种profile版本确定方法、系统、电子设备及计算机存储介质，涉及电子设备技术领域，解决了蓝牙设备间profile支持效果不佳的问题。具体方案为：外接设备采用第一PBAP版本向电子设备请求通讯录同步服务；电子设备根据第一PBAP版本向外接设备提供通讯录同步服务；在通讯录同步服务期间出现异常的情况下，外接设备向电子设备发送SDP请求信息；电子设备向外接设备发送第二SDP响应信息；其中，第二SDP响应信息包括第二PBAP标识；第二PBAP标识包括第二版本号，或包括第一版本号和取值为第二值的特定指示位；外接设备根据第二PBAP标识，采用第二PBAP版本向电子设备请求通讯录同步服务。

摘要： 本申请涉及一种profile更新方法及装置，涉及eSIM技术领域，该rofile更新方法包括以下步骤：获取目标profile文件，识别目标profile文件是否为预设profile类型；若目标profile文件为预设profile类型，解析获取目标profile文件内的第一PE，获得profile更新内容；识别profile更新内容对应的功能操作类型，并执行对应的功能操作；其中，第一PE包括profile更新内容。本申请对profile文件的组成进行重新设定，将传输数据量较多的profile重新下载方式修改为仅对profile增量或者更新的内容进行下载的方式，以提高更新效率和成功率。

摘要： 本发明公开了一种profile复制方法及装置，涉及计算机领域，该方法包括获取待实现的profile与已存在的profile之间的修改信息；将所述已存在的profile的ID和所述修改信息发送至虚拟卡；虚拟卡接收所述ID和修改信息并基于所述ID复制profile；基于所述修改信息修改复制得到的profile，得到待实现的profile。本发明能够减少下载数据量，从而有效保证下载成功率。