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A Method for Preparing An Extract of Antarctic Lichen Amandinea sp. and Composition Comprising the Extract of Amandinea sp.

机译:一种制备南极地衣鹅膏提取物的方法和包含鹅膏提取物的组合物。

摘要

The present invention relates to a method for producing an extract of Antarctic lichen Amandinea (Amandinea sp.) and to a pharmaceutical composition for preventing or treating inflammatory diseases comprising the extract as an active ingredient. Amandinea (Amandinea sp.) extract according to the present invention inhibits the production of pro-inflammatory cytokines and inflammatory mediators in RAW264.7 cells in vitro and zebrafish in vivo, and inactivates the NF-κB pathway, so that It can be usefully used for prophylactic or therapeutic purposes.
机译:本发明涉及一种生产南极苔藓鹅膏(鹅膏属)提取物的方法,以及一种用于预防或治疗炎症性疾病的药物组合物,其包含作为活性成分的提取物。根据本发明的Amandinea(Amandinea sp.)提取物抑制体外RAW264.7细胞和体内斑马鱼中促炎细胞因子和炎症介质的产生,并使NF-κB途径失活,因此其可有效用于预防或治疗目的。

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