Solid formulation for oral administration containing sacubitril and valsartan

摘要

The present invention is an oral solid preparation containing sacubitril/valsartan sodium salt trihydrate, which improves the preparation and storage stability through improvement of hygroscopicity and productivity of the pharmaceutical preparation, and at the same time reduces the risk that may occur during the manufacturing process, thereby reducing the risk of heart failure It can be preferably used as a therapeutic agent.