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Fermented product combination cancer therapy with immune checkpoint modulators and symbiotic microbiota

机译:带有免疫检查点调节剂和共生微生物群的发酵产品组合癌症治疗

摘要

PROBLEM TO BE SOLVED: To provide a method for treating cancer. The use of a combination of an immune checkpoint modulator and a fermentation composition for producing a pharmaceutical or kit for treating cancer, wherein the combination is more than the immune checkpoint modulator alone. The enhanced anti-cancer effect of the immune checkpoint modulator is provided, the immune checkpoint modulator is a PD-1 specific antibody or ligand thereof, and the fermentation composition comprises yeast and lactic acid bacteria. It is intended to contain multiple metabolites produced by fermentation of soybean or its extract by multiple microorganisms. [Selection diagram] None
机译:需要解决的问题:提供一种治疗癌症的方法。一种免疫检查点调节剂和发酵组合物的组合用于生产用于治疗癌症的药物或试剂盒的用途,其中所述组合多于仅免疫检查点调节剂。本发明提供了免疫检查点调节剂的增强抗癌效果,免疫检查点调节剂是PD-1特异性抗体或其配体,发酵组合物包括酵母和乳酸菌。其目的是含有由多种微生物发酵大豆或其提取物产生的多种代谢物。[选择图]无

著录项

  • 公开/公告号JP2022058740A

    专利类型

  • 公开/公告日2022-04-12

    原文格式PDF

  • 申请/专利号JP20220009064

  • 发明设计人 ルー クン-ミン;

    申请日2022-01-25

  • 分类号A61K36/48;A61K36/06;A61K39/395;A61K31/197;A61K31/19;A61K35/744;A61K35/747;A61K9/08;A61P43;A61P35;

  • 国家 JP

  • 入库时间 2022-08-25 00:30:58

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