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Composition for diagnosis of occupational asthma and method for diagnosis of occupational asthma using the same

机译:职业性哮喘诊断用组合物及使用其诊断职业性哮喘的方法

摘要

The present invention relates to a composition for diagnosing occupational asthma and a method for diagnosing occupational asthma using the same, and is presented with respect to a biomarker capable of diagnosing occupational asthma. The inventors of the present invention established an animal model induced by occupational asthma in order to establish a biometabolite monitoring database of occupational asthma in order to discover occupational asthma biomarkers, and a specific substance through analysis of metabolites in the animal model It was confirmed that this is a biomarker of occupational asthma. According to the present invention, occupational asthma can be easily distinguished from a sample by providing biomarkers through profiling and pattern analysis of metabolites for occupational asthma, and thus it can be usefully used in the treatment of occupational asthma.
机译:本发明涉及一种用于诊断职业性哮喘的组合物和使用该组合物诊断职业性哮喘的方法,并涉及一种能够诊断职业性哮喘的生物标记物。本发明的发明人建立了由职业性哮喘诱导的动物模型,以便建立职业性哮喘的生物代谢监测数据库,以便发现职业性哮喘生物标记物,并且通过对动物模型中的代谢物进行分析,确认这是职业性哮喘的生物标记物。根据本发明,通过对职业性哮喘的代谢物进行分析和模式分析,通过提供生物标记物,可以很容易地将职业性哮喘与样本区分开来,因此,它可以有效地用于职业性哮喘的治疗。

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