METHOD FOR PRODUCTION OF FAST, INCLUSIVE AND HIGH-DOSE INACTIVE ADJUVANT POSITIVE VACCINE TO BE USED AGAINST SARS-COV-2 VIRUS

摘要

The invention relates to the production method of inactive vaccine for SARS-CoV-2 virus. Said method comprises the following process steps; isolating and culturing SARS-CoV-2 virus, concentrating the obtained virus solution, applying the process of aliquoting at different times on behalf of the characterization of possible genome variation and determination of the pool content, applying gamma irradiation such that equal irradiation is provided in the tubes of concentrated virus so as to provide viral inactivation and sterilization, adding GM-CSF as adjuvant so as to increase immunogenicity, applying lyophilisation after the addition of GM-CSF as an adjuvant.