首页> 外国专利> Composition comprising Erigeron annuus (L.) Pers. for preventing or treating of Degenerative Brain Diseases

Composition comprising Erigeron annuus (L.) Pers. for preventing or treating of Degenerative Brain Diseases

机译:包含灯盏花的组合物。用于预防或治疗退化性脑疾病

摘要

The present invention relates to a composition for the prevention or treatment of degenerative brain disease, comprising an extract of Amanita fenugreek as an active ingredient. More specifically, the extract of the present invention increases the expression of antioxidant enzymes SOD2 (superoxide dismutase-2), CAT (catalase), and GPx (glutathione peroxidase), and promotes apoptosis, protein Bax (Bcl-2 Antagonist) X), inhibits the expression of caspase 3 and caspase 8 and promotes the expression of Bcl-XL (B-cell lymphoma-extra large) protein, which inhibits apoptosis Because it is excellent, it can be widely used as a pharmaceutical composition for preventing or treating degenerative brain disease or a food composition for preventing or improving degenerative brain disease.
机译:本发明涉及一种用于预防或治疗变性脑疾病的组合物,其包含胡芦巴鹅膏提取物作为活性成分。更具体地说,本发明提取物增加抗氧化酶SOD2(超氧化物歧化酶-2)、CAT(过氧化氢酶)和GPx(谷胱甘肽过氧化物酶)的表达,并促进凋亡、蛋白Bax(Bcl-2拮抗剂)X、抑制caspase 3和caspase 8的表达,并促进Bcl-XL(B细胞淋巴瘤超大)蛋白的表达,由于其性能优异,因此可广泛用作预防或治疗退行性脑疾病的药物组合物或预防或改善退行性脑疾病的食品组合物。

著录项

  • 公开/公告号KR102366476B1

    专利类型

  • 公开/公告日2022-02-23

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020190072808

  • 申请日2019-06-19

  • 分类号A61K36/28;A23L33/105;A61K31/05;A61K31/352;A61P25/28;

  • 国家 KR

  • 入库时间 2024-06-14 22:47:44

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