首页> 外国专利> Monoolein Cubic Phase Containing Hydrophobically Modified Gelatin, Hydrophobically Modified Polyethylenimine And Hydrophobically Modified Glucose Oxidase

Monoolein Cubic Phase Containing Hydrophobically Modified Gelatin, Hydrophobically Modified Polyethylenimine And Hydrophobically Modified Glucose Oxidase

机译:含有疏水性改性明胶,疏水改性的聚乙烯和疏水改性葡萄糖氧化酶的单烯醇醚立方相

摘要

In the present invention, hydrophobized gelatin and hydrophobized polyethyleneimine are fixed in a lipid bilayer to form a complex in the aqueous channel to close the aqueous channel. As this is opened, the active ingredient loaded in the water channel is released. In particular, the cubic monoolein phase of the present invention contains a hydrophobized glucose oxidase and senses glucose to open an aqueous channel, and its size is 100 nm or less, so it has an effect of easy skin penetration. Therefore, when a cosmetic product is manufactured using the monoolein of the present invention, there is an effect of penetrating deep into the skin or tissue and releasing the active ingredient mounted inside the aqueous channel only in an environment in which glucose is present.
机译:在本发明中,疏水化明胶和疏水化聚乙烯亚胺在脂质双层中固定在脂质双层中,以在水性通道中形成络合物以关闭含水通道。 如图所示,释放在水通道中的活性成分被释放。 特别地,本发明的立方体单烯醇型相含有疏水化的葡萄糖氧化酶,并感测葡萄糖以打开含水通道,其尺寸为100nm或更小,因此它具有易于皮肤渗透的效果。 因此,当使用本发明的单烯醇制造化妆品时,存在渗透到皮肤或组织中的效果,并仅在存在葡萄糖的环境中释放安装在水性通道内的活性成分。

著录项

  • 公开/公告号KR102345183B1

    专利类型

  • 公开/公告日2021-12-31

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020190164073

  • 发明设计人 김진철;김진아;김태훈;박석호;

    申请日2019-12-10

  • 分类号A61K8/02;A61K47/34;A61K47/42;A61K8/65;A61K8/84;A61K9;A61K9/127;A61Q19;

  • 国家 KR

  • 入库时间 2022-08-24 23:10:24

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