首页> 外国专利> Composition for preventing or treating cognitive disorder or psychiatric disorder comprising extracts of Dracocephalum moldavica

Composition for preventing or treating cognitive disorder or psychiatric disorder comprising extracts of Dracocephalum moldavica

机译:用于预防或治疗认知疾病或精神病疾病的组合物,包括Dracocephalum metavica的提取物

摘要

The present invention relates to a composition for preventing, improving, or treating cognitive dysfunction or mental disease, comprising an extract of Dracocephalum moldavica as an active ingredient, wherein the composition comprising the extract of the present invention inhibits PDE10A and activates CREB phosphorylation For the prevention, treatment or improvement of cognitive function disorders or mental disorders such as Alzheimer's disease, schizophrenia, forgetfulness or Huntington's disease, as it was confirmed that the effect of improving cognitive function was confirmed in the forgetfulness model administered with scopolamine and the schizophrenia model administered with MK-801. compositions and PDE10A inhibitors.
机译:本发明涉及用于预防,改善或治疗认知功能障碍或精神疾病的组合物,其包含Dracocephalum Metavica作为活性成分的提取物,其中包含本发明提取物的组合物抑制PDE10A并激活Creb磷酸化以预防 认知功能障碍或精神疾病如阿尔茨海默病,精神分裂症,遗忘或亨廷顿疾病的治疗或改善,因为它证实了改善认知功能的效果在用COLOPONAMINE给予的遗忘模型和施用MK施用的精神分裂症模型 -801。 组合物和PDE10A抑制剂。

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