The present invention relates to a composition for preventing, improving, or treating cognitive dysfunction or mental disease, comprising an extract of Dracocephalum moldavica as an active ingredient, wherein the composition comprising the extract of the present invention inhibits PDE10A and activates CREB phosphorylation For the prevention, treatment or improvement of cognitive function disorders or mental disorders such as Alzheimer's disease, schizophrenia, forgetfulness or Huntington's disease, as it was confirmed that the effect of improving cognitive function was confirmed in the forgetfulness model administered with scopolamine and the schizophrenia model administered with MK-801. compositions and PDE10A inhibitors.
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