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NALOXONE PHARMACEUTICAL FORMULATIONS FOR INTRANASAL (IN) DELIVERY

机译:鼻内碱(IN)递送的纳洛酮药物制剂

摘要

The present disclosure introduces intranasal (IN) pharmaceutical formulations having naloxone or an opioid antagonist as the active agent, and an absorption enhancer, such as a bile acid, or a salt thereof, for IN delivery. The bile acid, or salt thereof, enhances absorption of naloxone or an opioid antagonist into the bloodstream of a human subject.
机译:本公开介绍了具有纳洛酮或阿片类药物作为活性剂的鼻内(In)药物制剂,以及用于递送的吸收增强剂,例如胆汁酸或其盐。 胆汁酸或其盐,增强了纳洛酮或阿片类拮抗剂的吸收到人受试者的血液中。

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