The present invention relates to a recombinant spike protein of Corona-19 virus that forms a trimer, and a method for mass production of the recombinant spike protein in a plant, in detail, forming a trimer for the purpose of enhancing immunogenicity and effective antigen delivery It relates to a method for designing a recombinant gene expressing the recombinant Spike protein of the Corona-19 virus, and to a method for mass-producing the recombinant Spike recombinant protein in a plant.
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