COMPANION DIAGNOSTIC BIOMARKER COMPOSITION AND COMPANION DIAGNOSTIC KIT COMPRISING THE SAME

摘要

The present invention relates to a biomarker composition for companion diagnosis and a kit for companion diagnosis comprising the same, and specifically, one of PD-1 Checkpoint Inhibitor and PD-L1 Checkpoint Inhibitor. It relates to a companion diagnostic biomarker composition for predicting a therapeutic response to any one or more immune checkpoint inhibitors, and a companion diagnostic kit comprising the same. According to the present invention, it is possible to predict the therapeutic response of any one or more immune checkpoint inhibitors of PD-1 immune checkpoint inhibitor and PD-L1 immune checkpoint inhibitor through proteomic analysis in the blood of cancer patient as well as companion diagnosis through tissue of cancer patient. can have an effect. In addition, the biomarker composition for companion diagnosis and the companion diagnosis kit comprising the same according to the present invention include a reactive patient group and It has the advantage of high accuracy in screening non-responding patients who do not show the effect.