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Time independent viscoelastic analysis parameter for prediction of patient outcome

机译:预测患者结果的时间独立粘弹性分析参数

摘要

In some embodiments, the invention provides an in vitro method for identifying a patient as likely as likely to require a transfusion of at least six units of blood in six hours or less. The method comprise, consists essentially of, or consists of (a) analyzing a sample of blood from a patient with a viscoelastic analysis assay to obtain a coagulation characteristic value that is independent of time of the patient; and (b) comparing the coagulation characteristic value of the patient to a coagulation characteristic value that is independent of time of a control,;wherein the coagulation characteristic value of the patient that is lower than the coagulation characteristic value of the control identifies the patient as likely to require a transfusion of at least six units of blood in six hours or less.
机译:在一些实施方案中,本发明提供了一种体外方法,用于鉴定患者,其可能需要在六小时或更短的时间内需要输血至少六个血液。 该方法包括基本上包括(a)(a)与粘弹性分析测定的患者分析血液样品,以获得与患者的时间无关的凝血特征值; (b)将患者的凝血特征值与对照的时间无关的凝固特征值比较;其中低于对照的凝固特征值的患者的凝固特征值鉴定了患者 可能需要在六小时或更短的时间内输血至少六个单位的血液。

著录项

  • 公开/公告号US11187710B2

    专利类型

  • 公开/公告日2021-11-30

    原文格式PDF

  • 申请/专利号US201615580968

  • 发明设计人 MICHAEL P. CHAPMAN;

    申请日2016-06-07

  • 分类号G01N33/86;A61B5/02;G01N11/02;G01N33/49;A61B5;G01N11;G16H50/70;A61B5/15;A61B5/154;

  • 国家 US

  • 入库时间 2022-08-24 22:15:41

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