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COMPOSITIONS FOR MODULATING GUT MICROFLORA POPULATIONS, ENHANCING DRUG POTENCY AND TREATING VIRAL INFECTIONS, AND METHODS FOR MAKING AND USING SAME

机译:用于调节肠道微生物群的组合物,增强药物效力和治疗病毒感染,以及制造和使用的方法

摘要

Provided are compositions, including products of manufacture and kits, and methods, comprising combinations of microbes, such as non-pathogenic, live bacteria and/or bacterial spores, for the control, amelioration, prevention, and treatment of a disease or condition, for example, a viral infection such as a COVID19 infection, and these non-pathogenic, live bacteria and/or bacterial spores can be administered to an individual, thereby resulting in a modification or modulation of the individual's gut microfloral population(s), and by modulating or modifying the individual's gut microbial population(s) using compositions, products of manufacture and methods as provided herein, the pharmacodynamics or effectiveness of a drug or a vaccine administered to the individual is altered, for example, the pharmacodynamics of the drug or vaccine is enhanced, the individual's ability to absorb a drug is modified or the dose efficacy of a drug or vaccine is increased.
机译:提供的是组合物,包括制造和套件的产品,以及包含微生物组合的方法,例如非致病性,活细菌和/或细菌孢子,用于对照,改善,预防和治疗疾病或病症 例如,可以向个体施用诸如Covid19感染等病毒感染,以及这些非致病性,活细菌和/或细菌孢子,从而导致个体的肠道微氯群体的改性或调节,以及 使用组合物,制造和方法的产品调节或改变个体的肠道微生物群体,药物动力学或给予个体的疫苗的药物动力学或有效性被改变,例如药物或疫苗的药效学 增强,修饰了个体吸收药物的能力或药物或疫苗的剂量功效增加。

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