The present invention relates to a method for predicting the prognosis of a patient with advanced breast cancer, and more particularly, to a method for predicting the prognosis of an advanced breast cancer by a combination of a proliferation-related gene and an immune-related gene. The method of the present invention has the effect of more accurately predicting the future metastasis, recurrence or metastatic recurrence of patients with advanced breast cancer, and the prognosis for disease-free/metastatic survival rate, suggesting a clue for the future direction of breast cancer treatment It can be useful for the purpose of
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