USE OF TRITERPENOID NRF2 INHIBITORS

摘要

Described herein are terpinoid derivatives as NRF2 inhibitors for use in treating systemic lupus nephritis, diabetic chronic kidney disease (CDK), Alport syndrome, focal segmental glomerulosclerosis (FSGS), pulmonary hypertension, Friedreich's ataxia, autosomal dominant polycystic kidney disease (ADPKD), or IgA nephropathy.