METHOD FOR PREDICTING PREMATURE BIRTH IN WOMEN WITH THREATENED EARLY MISCARRIAGE AND RECURRENT MISCARRIAGE IN HISTORY

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to obstetrics and gynecology, and can be used to predict premature birth in women with threatened miscarriage within 5-12 weeks and a history of recurrent miscarriage. In the peripheral venous blood of pregnant women with a threatening miscarriage and recurrent miscarriage in the anamnesis in the period of 5-12 weeks of gestation, before the appointment of conserving therapy, the relative content of IL-4 positive monocytes is determined. If its value is equal to 26.7% or less, preterm labor is predicted. The method can be used as a screening method, since it is simple in execution, has high accuracy, sensitivity and specificity, it involves the study of one immunological indicator.;EFFECT: invention allows predicting premature birth in women with habitual miscarriage from early gestation, which will make it possible to carry out preventive measures in a timely manner and reduce the risk of preterm birth.;1 cl, 1 tbl, 3 ex