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INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE, COMPOSITIONS AND USES THEREOF

机译:烟酰胺N-甲基转移酶,组合物及其用途的抑制剂

摘要

Disclosed are compounds and pharmaceutically acceptable salts thereof, which are useful as inhibitors nicotinamide N-methyltransferase (NNMT). Also disclosed are pharmaceutical compositions comprising a compound disclosed herein. Related methods of treating cancer in a subject and methods of inhibiting tumor growth in subject are also disclosed.
机译:公开了一种化合物和药学上可接受的盐,其可用作抑制剂烟酰胺N-甲基转移酶(NNMT)。 还公开了包含本文公开的化合物的药物组合物。 还公开了治疗癌症的相关方法及抑制受试者肿瘤生长的方法。

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