STRAIN OF HCOV-19/RUSSIA/OMSK-202118-1707/2020 OF SARS-COV-2 CORONAVIRUS, IMMUNOSORBENT CONTAINING PURIFIED WHOLE VIRION ANTIGEN OBTAINED ON BASIS OF SPECIFIED STRAIN AND ISA TEST SYSTEM FOR DETECTING ANTIBODIES OF CLASSES M, G AND A TO SARS CORONAVIRUS-COV-2 USING SPECIFIED IMMUNOSORBENT

摘要

FIELD: medicine.;SUBSTANCE: invention relates to the hCoV-19/Russia/Omsk-202118-1707/2020 strain of the SARS-CoV-2 virus, an immunosorbent containing a whole virion antigen obtained using said strain, and an ELISA test system for detecting antibodies of classes M, G and A to the SARS-CoV-2 coronavirus and can be used in medical virology. The specified technical result is achieved by obtaining the hCoV-19/Russia/Omsk-202118-1707/2020 strain of the SARS-CoV-2 virus deposited in the State collection of viral pathogens and rickettsioses of the FBSI SSC VB Vector of Rospotrebnadzor. The specified technical result is also achieved by obtaining an immunosorbent containing the whole virion antigen of the SARS-CoV-2 virus, used as a component of an enzyme-linked immunosorbent assay for detecting antibodies of classes M, G and A to the SARS-CoV-2 virus. The specified technical result is also achieved by the manufacture of an enzyme-linked immunosorbent assay for detecting antibodies of classes M, G and A to the SARS-CoV-2 virus containing the above immunosorbent.;EFFECT: invention increases the sensitivity of a set of reagents for a two-stage solid-phase indirect enzyme-linked immunosorbent assay (ISA) using a whole virion antigen obtained on the basis of the claimed hCoV-19/Russia/Omsk-202118-1707/2020 strain of the SARS-CoV-2 virus.;4 cl, 11 tbl, 7 ex