The present invention discloses a negative pressure isolation hood, and relates to the infectious disease treatment and transfer field. The negative pressure isolation hood includes a hood, a half-length outerwear, an exhaust hose, and an air-exhaust filtration system, where the hood is disposed above the half-length outerwear and is in air tight connection with the half-length outerwear, the hood is connected to the air-exhaust filtration system through the exhaust hose, and a one-way air inlet valve is disposed at the top of the hood. The negative pressure isolation hood in the present invention is used by an infectious disease patient without impeding free movement of the infectious disease patient, ensuring normal and unrestricted movement of the wearer's head and neck, and the exhaust air filtration system is small in size and is easy to carry.
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