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High titer recombinant AAV vector production in adherent and suspension cells
High titer recombinant AAV vector production in adherent and suspension cells
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机译:高滴度重组AAV载体在粘附和悬浮细胞中产生
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摘要
The present invention is directed to an in vitro method of producing a recombinant AAV virion in a mammalian host cell that comprises a functional adenoviral E1A gene and rAAV virions made by the method. Host cells are transfected with varying ratios of plasmids comprising the E1A gene and virions.
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