INHIBITION OF HISTONE METHYL TRANSFERASES TO TREAT CANCER

摘要

KMT9, METTL21A and METTL21B, are characterized herein for the first time as histone methyl transferases involved in the proliferation of cancer cells. Inhibitors of the same can be used for treating cancer. The present invention concerns, inter alia, a selective KMT9- inhibitor for use in the treatment of cancer, in particular prostate cancer.