METHOD FOR MONITORING AND MANAGEMENT OF CELL LINES USING PERIODIC LOW-COVERAGE DNA SEQUENCING DATA

摘要

A method and system are provided for tracking and verifying cell populations that constitute a given cell lineage. By tracking the creation of cell populations along the cell lineage as a directed tree, it is possible to verify multiple cell populations using a single cell population. Similarly it is possible to detect potentially anomalous cell populations by performing a verification determination on a single cell population.