Composition for the prevention and treatment of skin ailment, including Pleurotus cornucopiae and Rehmannia glutinosa complex extract as an active ingredient

摘要

The present invention relates to a composition for preventing and treating skin diseases, comprising a complex extract of Pleurotus cornucopiae (variety: long-dari) and rehmannia ( Rehmannia glutinosa; variety: multiganga) as an active ingredient. The extract of yellow oyster mushroom and Rehmannia glutinosa of the present invention effectively reduces nitric oxide (NO; nitric oxide) production and the expression of inflammatory cytokines TNF-α, IL-1β, IL-6, PEG2, iNOS and COX-2 By doing so, it can be usefully used as a pharmaceutical composition for preventing and treating skin diseases, a quasi-drug composition for preventing and improving skin diseases, a cosmetic composition for preventing and improving skin diseases, and a health functional food composition for preventing and improving skin diseases.