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Cyclic peptide compound having Kras inhibitory action

机译:具有KRAS抑制作用的环状肽化合物

摘要

Cyclic peptide compounds that interact with Ras and unnatural amino acids useful for the preparation of the cyclic peptide compounds have been discovered. Moreover, it was discovered that the said cyclic peptide compound inhibited the binding of Ras and SOS. In addition, a specific non-natural amino acid contained in the cyclic peptide compound and a method for producing the same were discovered.
机译:已经发现,已经发现了与Ras和非天然氨基酸相互作用的环状肽化合物已经发现了用于制备环状肽化合物。此外,发现所述环肽化合物抑制Ras和SOS的结合。此外,发现了环状肽化合物中含有的特定非天然氨基酸及其制备方法。

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