ANTICANCER DRUG FOR ORAL USE

摘要

FIELD: medicine. ;SUBSTANCE: invention relates to medicine, namely to anticancer drugs for oral use. The proposed tool in the form of a tablet contains methyl ester of Nα-tert-butyloxycarbonyl-S-tetrahydropyranylcysteinyl-phenylalanyl-D-tryptophyl-Nε-benzyl-oxycarbonyl-lysyltreonine and auxiliary substances: starch, lactose, talc, magnesium stearate, magnesium carbonate and lemon acid, at a certain quantitative ratio. ;EFFECT: composition of the product ensures good automatic dosing on any existing automatic line for the production of tablets, while the production technology excludes the granulation stage. The tool is convenient to use, since it contains the required dose of the active substance in a unit dosage form, it can be used on an outpatient basis. The low amount of lactose allows the drug to be used by patients with hypolactasia. The invention shows high biological activity, which is equivalent to the prototype.;1 cl, 1 tbl, 3 ex