A double-stranded oligonucleotide comprising CTGF specific sequence and a composition for treating and preventing fibrosis related diseases and respiratory related diseases

摘要

The present invention relates to a double-stranded oligonucleotide capable of inhibiting CTGF expression with high specificity and high efficiency, a double-stranded oligonucleotide construct and nanoparticles comprising the double-stranded oligonucleotide, and a use thereof for the prevention or treatment of fibrosis or respiratory disease will be.