Interleukin-10 fusion protein and its use

摘要

Improved productivity and stability for IL-10 fusion proteins based on known antibody fragments (e.g., scFv, DIA body, FAB) Provides a fusion protein with antibodies and interleukin-10 (IL-10) having a number of advantages including a significant increase in biological activity due to the serum half-life and the binding of the target antigen.The fusion protein of IgG class antibody and IL-10 molecule is a fusion protein comprising two identical heavy chain polypeptides and two identical light chain polypeptides.No selection