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Methods of using chimeric antigen receptors targeting B-cell maturation antigen and uses thereof
Methods of using chimeric antigen receptors targeting B-cell maturation antigen and uses thereof
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机译:靶向B细胞成熟抗原的嵌合抗原受体的方法及其用途
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摘要
The presently disclosed subject matter provides for methods and compositions for treating multiple myeloma. It relates to chimeric antigen receptors (CARs) that specifically target B cell maturation antigen (BMCA), and immunoresponsive cells comprising such CARs. The presently disclosed BMCA-specific CARs have enhanced immune-activating properties, including anti-tumor activity.
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