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The Use of Non-Steroidal Mineralocorticoid Receptor Antagonists Alone or in Combination for the Treatment of Muscular or Neuromuscular Diseases
The Use of Non-Steroidal Mineralocorticoid Receptor Antagonists Alone or in Combination for the Treatment of Muscular or Neuromuscular Diseases
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机译:单独使用非甾体型矿物质激素受体拮抗剂或组合用于治疗肌肉或神经肌肉疾病
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摘要
The present invention relates to non-steriodal mineralocorticoid receptor (MR) and the pharmacology of mineralocorticoid receptor antagonists (MR Antagonists, MRAs). In particular, the invention relates to the use of MRAs alone and in combination preferably in combination with sGC stimulators and/or sGC activators for preparation of medicaments for the prevention and/or treatment of muscular or neuromuscular diseases, especially for the treatment of Duchenne Muscular Dystrophy (DMD).
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