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Hydrozincite containing zinc carbonate hydroxide hydrate and method of making

机译:含氢碳酸锌氢氧化物水合物的羟齐齐齐齐齐。和制造方法

摘要

An inorganic composition that is useful as an active ingredient for pharmaceuticals and has excellent stability comprises hydrozincite-containing zinc carbonate hydroxide hydrate produced by drying a precipitate. The precipitate is obtained by adding aqueous zinc nitrate solution, aqueous zinc sulfate solution or aqueous zinc chloride solution and aqueous sodium hydroxide solution dropwise to aqueous sodium hydrogen carbonate solution, a pH of the aqueous sodium hydrogen carbonate solution being maintained within a range of 6.5 to 9 by means of a pH controller. The hydrozincite-containing zinc carbonate hydroxide hydrate has an amount of dissolved Zn2+ ions of not less than 0.1 μg/m2 but not more than 7.33 μg/m2 and pH of not less than 7.2 and less than 8.3 after a dissolution test using stirring method.
机译:可用作药物的活性成分的无机组合物,具有优异的稳定性,包括通过干燥沉淀而产生的含氢锌碳酸锌水合物。通过将硝酸锌水溶液,硫酸锌水溶液或氯化锌水溶液和氢氧化钠水溶液滴加到碳酸氢钠水溶液中,将溶液水溶液,碳酸氢钠水溶液的pH维持在6.5至5.5至5点范围内9通过pH控制器。含羟齐齐齐齐的碳酸锌水合物的溶解Zn 2+ 2+ 2+的量不小于0.1μg/ m 2 但不超过7.33μg/ m 和pH不小于7.2且小于8.3。

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