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Saccharide Derivative of a Toxic Payload and Antibody Conjugates Thereof
Saccharide Derivative of a Toxic Payload and Antibody Conjugates Thereof
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机译:脂肪糖衍生物的有毒有效载荷和抗体缀合物
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摘要
A molecule comprising a saccharide bound via an O-glycosidic bond to a hydroxyl group of a toxic payload molecule is disclosed. An antibody-drug conjugate comprising an antibody covalently bound to a toxic payload molecule, optionally via a linker group, and a saccharide bound via an O-glycosidic bond to a hydroxyl group of the toxic payload molecule is further disclosed.
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