i) a spatially truncated optical lens, the substantially planar surface of which is inclined about an axis to reflect light transmitted between the proximal and distal ends of the probe, internally into the body of the lens. An optical lens, and ii) sequentially with an optical lens on the axis of the probe while the optical and electrical members of the probe, which simultaneously transmit radiant and mechanical energies (which the probe exchanges with the target body vessel) are parallel to each other within the housing of the probe. A hybrid NIRF/IVUS imaging probe comprising a placed acoustic transducer is disclosed. The method of operating the probe results in the formation of spatially co-registered optical and acoustic images of the target. Related imaging systems and computer program products.
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