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NAPHTHYLAMINE COMPOUND AND BIOLOGICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

机译:萘胺化合物及其生物学上可接受的盐,其制备方法及其应用

摘要

In view of the lack of targeted anticancer drugs in the prior art, provided is a naphthylamine compound and a biologically acceptable salt thereof, a preparation method therefor, and an application thereof. The naphthylamine compound and the biologically acceptable salt thereof provided in the present invention can bind to a protein site related to a neoplastic disease in an organism by means of a functional group in the structure thereof, and hydrogen bonding and hydrophobic interaction occurs with a receptor so as to achieve the purpose of inhibiting tumor cell proliferation.
机译:鉴于现有技术中缺乏靶向抗癌药物,提供了萘胺化合物及其生物学可接受的盐,其制备方法及其应用。本发明中提供的萘胺化合物及其生物可接受的盐可以通过在其结构中的官能团中的官能团与生物体中的肿瘤疾病相关的蛋白质位点结合,并且氢键和疏水相互作用与受体发生如此至于达到抑制肿瘤细胞增殖的目的。

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