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A method for the production of 1, 6 - dibromo - 1, 6 - didesoxydulcit

机译:一种生产1,6-二溴-1,6-二脱氧杜尔西的方法

摘要

The title compound is prepared by reacting dulcitol with an aqueous HBr solution containing more than 47% HBr in a closed system under pressure at 60-80 DEG C. for 9.0-0.5 hours.ALSO:Pharmaceutical compositions showing cytostatic activity comprise 1,6-dibromo-1,6-dideoxydulcitol and a carrier therefor. Carriers exclude water and other solvents which form known solutions with the active ingredient. The compositions may be formulated as tablets, pills, capsules, suppositories or injections.
机译:标题化合物是通过使二甘醇与封闭溶液中的含47%以上HBr的HBr水溶液在60-80℃的压力下反应9.0-0.5小时而制得的。二溴1,6-二脱氧二蔗糖醇及其载体。载体不包括水和其他与活性成分形成已知溶液的溶剂。该组合物可以配制成片剂,丸剂,胶囊剂,栓剂或注射剂。

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