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this has the effect of acth peptides and their

机译:这会影响acth肽及其

摘要

The peptides, their amides or acid addition salts are prepd. either by (1) eliminating the protective groups in peptides having ACTH activity which have as the main amino acid an acid with D configuration and in which the alpha-amino group is acylated and the amino groups of the side chains and the terminal and side chain carboxyl groups are protected, or by (2) acylating, at the alpha-N, ACTH effect peptides in which the main amino acid has D configuration and opt. converting the products into their acid addition salts.
机译:制备肽,其酰胺或酸加成盐。通过(1)消除具有ACTH活性的肽中的保护基,所述保护基具有D构型的酸作为主要氨基酸,其中α-氨基被酰化并且侧链和末端和侧链的氨基羧基被保护,或通过(2)酰化在α-N处的ACTH效应肽,其中主要氨基酸具有D构型和opt。将产物转化为其酸加成盐。

著录项

  • 公开/公告号BE751741A

    专利类型

  • 公开/公告日1970-12-10

    原文格式PDF

  • 申请/专利权人 CIBA S.A. BALE SUISSE;

    申请/专利号BED751741

  • 发明设计人

    申请日1970-06-10

  • 分类号C07G;A61K;

  • 国家 BE

  • 入库时间 2022-08-23 10:18:38

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